Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways

Aging is a general degenerative process related to deterioration of cell functions in the entire organism. Mitochondria, which play a key role in energy homeostasis and metabolism of reactive oxygen species (ROS), require lifetime control and constant renewal. This explains recently peaked interest...

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Bibliographic Details
Published in:Frontiers in genetics Vol. 10; p. 435
Main Authors: Gureev, Artem P., Shaforostova, Ekaterina A., Popov, Vasily N.
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 14.05.2019
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ISSN:1664-8021, 1664-8021
Online Access:Get full text
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