Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq
Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host...
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| Vydáno v: | Frontiers in immunology Ročník 6; s. 23 |
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| Jazyk: | angličtina |
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Frontiers Media S.A
04.02.2015
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| ISSN: | 1664-3224, 1664-3224 |
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| Abstract | Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne's disease. Here, we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a 6-h infection time course with non-infected controls. We observed 245 and 574 differentially expressed (DE) genes in MAP-infected versus non-infected control samples (adjusted P value ≤0.05) at 2 and 6 h post-infection, respectively. Functional analyses of these DE genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix(®) microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection. |
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| AbstractList | Johne’s disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne’s disease. Here, we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a 6-h infection time course with non-infected controls. We observed 245 and 574 differentially expressed (DE) genes in MAP-infected versus non-infected control samples (adjusted P value ≤0.05) at 2 and 6 h post-infection, respectively. Functional analyses of these DE genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix® microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection. Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne's disease. Here, we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a 6-h infection time course with non-infected controls. We observed 245 and 574 differentially expressed (DE) genes in MAP-infected versus non-infected control samples (adjusted P value ≤0.05) at 2 and 6 h post-infection, respectively. Functional analyses of these DE genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix(®) microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection.Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne's disease. Here, we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a 6-h infection time course with non-infected controls. We observed 245 and 574 differentially expressed (DE) genes in MAP-infected versus non-infected control samples (adjusted P value ≤0.05) at 2 and 6 h post-infection, respectively. Functional analyses of these DE genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix(®) microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection. Johne’s disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne’s disease. Here we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a six-hour infection time course with non-infected controls. We observed 245 and 574 differentially expressed genes in MAP-infected versus non-infected control samples (adjusted P value ≤ 0.05) at 2 and 6 hours post-infection, respectively. Functional analyses of these differentially expressed genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix® microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection. Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious economic consequences for cattle production in the United States and elsewhere. During infection, MAP bacilli are phagocytosed and subvert host macrophage processes, resulting in subclinical infections that can lead to immunopathology and dissemination of disease. Analysis of the host macrophage transcriptome during infection can therefore shed light on the molecular mechanisms and host-pathogen interplay associated with Johne's disease. Here, we describe results of an in vitro study of the bovine monocyte-derived macrophage (MDM) transcriptome response during MAP infection using RNA-seq. MDM were obtained from seven age- and sex-matched Holstein-Friesian cattle and were infected with MAP across a 6-h infection time course with non-infected controls. We observed 245 and 574 differentially expressed (DE) genes in MAP-infected versus non-infected control samples (adjusted P value ≤0.05) at 2 and 6 h post-infection, respectively. Functional analyses of these DE genes, including biological pathway enrichment, highlighted potential functional roles for genes that have not been previously described in the host response to infection with MAP bacilli. In addition, differential expression of pro- and anti-inflammatory cytokine genes, such as those associated with the IL-10 signaling pathway, and other immune-related genes that encode proteins involved in the bovine macrophage response to MAP infection emphasize the balance between protective host immunity and bacilli survival and proliferation. Systematic comparisons of RNA-seq gene expression results with Affymetrix(®) microarray data generated from the same experimental samples also demonstrated that RNA-seq represents a superior technology for studying host transcriptional responses to intracellular infection. |
| Author | MacHugh, David E. Park, Stephen D. E. Hokamp, Karsten Casey, Maura E. Meade, Kieran G. Taraktsoglou, Maria Magee, David A. Nalpas, Nicolas C. Browne, John A. Gormley, Eamonn Killick, Kate E. |
| AuthorAffiliation | 5 Tuberculosis Diagnostics and Immunology Research Centre, UCD School of Veterinary Medicine, University College Dublin , Dublin , Ireland 4 Systems Biology Ireland, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland 7 UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland 3 Biological Agents Unit, Health and Safety Executive , Leeds , UK 2 Animal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc , Dunsany , Ireland 1 Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin , Dublin , Ireland 6 Smurfit Institute of Genetics, Trinity College Dublin , Dublin , Ireland |
| AuthorAffiliation_xml | – name: 2 Animal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc , Dunsany , Ireland – name: 6 Smurfit Institute of Genetics, Trinity College Dublin , Dublin , Ireland – name: 7 UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland – name: 3 Biological Agents Unit, Health and Safety Executive , Leeds , UK – name: 1 Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin , Dublin , Ireland – name: 5 Tuberculosis Diagnostics and Immunology Research Centre, UCD School of Veterinary Medicine, University College Dublin , Dublin , Ireland – name: 4 Systems Biology Ireland, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland |
| Author_xml | – sequence: 1 givenname: Maura E. surname: Casey fullname: Casey, Maura E. – sequence: 2 givenname: Kieran G. surname: Meade fullname: Meade, Kieran G. – sequence: 3 givenname: Nicolas C. surname: Nalpas fullname: Nalpas, Nicolas C. – sequence: 4 givenname: Maria surname: Taraktsoglou fullname: Taraktsoglou, Maria – sequence: 5 givenname: John A. surname: Browne fullname: Browne, John A. – sequence: 6 givenname: Kate E. surname: Killick fullname: Killick, Kate E. – sequence: 7 givenname: Stephen D. E. surname: Park fullname: Park, Stephen D. E. – sequence: 8 givenname: Eamonn surname: Gormley fullname: Gormley, Eamonn – sequence: 9 givenname: Karsten surname: Hokamp fullname: Hokamp, Karsten – sequence: 10 givenname: David A. surname: Magee fullname: Magee, David A. – sequence: 11 givenname: David E. surname: MacHugh fullname: MacHugh, David E. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25699042$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.smim.2014.10.002 10.1016/j.vetimm.2011.12.005 10.1186/2046-0481-62-9-597 10.1128/IAI.71.11.6487-6498.2003 10.1093/nar/gkt214 10.1146/annurev-immunol-032712-095939 10.3389/fcimb.2013.00062 10.1002/eji.201040331 10.1016/j.coi.2011.06.002 10.1371/journal.ppat.1002769 10.1007/978-3-540-74805-2_5 10.1016/j.immuni.2012.09.015 10.1016/j.copbio.2012.09.004 10.1038/ni.2474 10.1186/gb-2009-10-4-r42 10.1038/nprot.2009.97 10.1186/1471-2164-13-186 10.1101/gr.079558.108 10.1017/s1466252307001168 10.1186/gb-2004-5-10-r80 10.1016/j.coi.2013.08.003 10.4049/jimmunol.1101620 10.1016/S0147-9571(02)00070-X 10.1093/bioinformatics/btt656 10.1016/j.cimid.2012.01.004 10.4049/jimmunol.159.6.2941 10.1093/bioinformatics/bts635 10.1016/j.cvfa.2011.07.001 10.1534/genetics.110.114983 10.1016/j.vetimm.2010.12.002 10.1128/IAI.00575-13 10.1079/9781845936136.0109 10.1016/j.smim.2014.09.010 10.1016/S0167-5877(00)00098-2 10.3389/fimmu.2014.00422 10.1128/IAI.00406-12 10.1128/IAI.06322-11 10.1093/bfgp/elr005 10.1016/j.vetimm.2010.10.008 10.1016/j.chom.2008.03.003 10.1016/S0749-0720(15)30408-4 10.1038/nmeth.1226 10.1111/j.1600-065X.2010.00994.x 10.1016/j.cell.2010.01.040 10.1126/science.1158441 10.3109/1040841x.2011.649712 10.1111/cmi.12161 10.3389/fimmu.2014.00396 10.1038/nrg2934 10.1016/j.tube.2014.04.004 10.1016/S0378-1135(00)00312-6 10.1186/1297-9716-43-25 10.1136/vr.140.6.141 10.1354/vp.45-6-829 10.1016/j.cvfa.2011.07.012 10.1038/mi.2011.7 10.1111/j.1939-1676.2011.00854.x 10.3389/fmicb.2012.00215 10.1016/j.vetimm.2008.10.294 10.1038/nature07002 10.1016/S0378-1135(00)00310-2 10.1186/2045-3701-2-26 10.1111/imm.12371 10.1093/bfgp/elq009 10.1080/01652176.2001.9695105 10.3168/jds.2011-4787 10.5588/ijtld.12.0246 10.2202/1544-6115.1027 10.1002/art.21141 10.2460/ajvr.2005.66.721 10.1016/S0378-1135(00)00331-X 10.1111/febs.12961 10.1189/jlb.0307147 10.1016/j.cbpa.2012.12.008 10.1093/bioinformatics/btl033 10.1016/j.ijmm.2007.03.003 10.4049/jimmunol.1100500 10.3389/fimmu.2014.00536 10.1186/1471-2164-11-282 10.1101/gr.124321.111 10.1371/journal.pone.0075924 10.1016/S1570-9639(03)00053-0 10.1186/1471-2164-14-694 10.1080/01652176.2002.9695120 10.1371/journal.pone.0032034 10.1371/journal.pone.0078644 10.1128/iai.72.6.3089-3096.2004 10.1016/j.smim.2009.05.011 10.1093/nar/gks1193 10.1093/bioinformatics/btp616 10.1186/1471-2180-6-10 10.1093/bioinformatics/btm478 10.1126/science.1160342 10.1111/j.2517-6161.1995.tb02031.x 10.1016/j.coi.2006.11.005 10.1186/gb-2010-11-2-r14 10.3109/1040841x.2010.532480 10.1186/1471-2164-14-230 10.1016/j.dci.2013.02.004 10.1186/1471-2164-12-628 10.1111/j.1865-1682.2009.01082.x |
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| Copyright | Copyright © 2015 Casey, Meade, Nalpas, Taraktsoglou, Browne, Killick, Park, Gormley, Hokamp, Magee and MacHugh. 2015 |
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| Keywords | RNA-sequencing microarray Mycobacterium avium subspecies paratuberculosis Johne’s disease immune response transcriptome macrophage cattle |
| Language | English |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: Uday Kishore, Brunel University, UK Reviewed by: Anthony George Tsolaki, Brunel University, UK; Annapurna Nayak, Brunel University, UK This article was submitted to Molecular Innate Immunity, a section of the journal Frontiers in Immunology. |
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| References | Guida (B93) 2011; 12 Smyth (B46) 2004; 3 Tarazona (B96) 2011; 21 Iturbide (B70) 2014 Barrett (B42) 2013; 41 Nielsen (B7) 2000; 44 Young (B41) 2010; 11 Lamont (B53) 2013; 14 Coussens (B75) 2010 Kabara (B65) 2010; 9 McLoughlin (B33) 2014; 5 Mortazavi (B58) 2008; 5 MacHugh (B48) 2009; 56 Bradford (B98) 2010; 11 Janagama (B19) 2006; 6 Ferwerda (B18) 2007; 82 Guerra-Laso (B54) 2015; 144 Marioni (B97) 2008; 18 Robertson (B4) 2012; 38 MacHugh (B30) 2012; 43 Mishra (B85) 2013; 14 Bannantine (B49) 2010; 138 Wilhelm (B61) 2008; 453 Boelaert (B5) 2000; 77 Sultan (B60) 2008; 321 Lamont (B77) 2012; 80 Coussens (B10) 2012; 35 Sweeney (B11) 1996; 12 Nalpas (B29) 2013; 14 Sommer (B72) 2009; 128 Benjamini (B40) 1995; 57 Good (B8) 2009; 62 Weiss (B24) 2008; 45 Muskens (B6) 2000; 77 Greig (B1) 1997; 140 Sweeney (B21) 2011; 27 Taraktsoglou (B31) 2011; 140 Dobin (B34) 2013; 29 Marfell (B66) 2013; 40 Kang (B83) 2013; 38 Redford (B87) 2011; 4 Lombard (B12) 2011; 27 Stabel (B20) 2006; 7 Souza (B26) 2013; 8 Lang (B67) 2008; 184 Rachman (B47) 2007; 297 Durinck (B39) 2009; 4 Dore (B27) 2012; 26 Suttles (B73) 2009; 21 Maertzdorf (B50) 2012; 16 Fitzgerald (B78) 2010; 40 Auer (B95) 2010; 185 Sollberger (B82) 2012; 188 Stabel (B13) 2000; 77 Bannantine (B15) 2013; 81 Rohde (B52) 2012; 8 Hostetter (B68) 2003; 26 Coussens (B64) 2003; 71 Fasold (B101) 2012; 13 Delbridge (B16) 2007; 19 Briken (B79) 2013; 3 Over (B2) 2011; 37 Gentleman (B43) 2004; 5 Shen (B71) 2005; 52 Cho (B9) 2012; 95 Magee (B32) 2012; 7 Huynh (B90) 2011; 23 Weiss (B86) 2005; 66 Robinson (B38) 2010; 26 Killick (B55) 2014; 5 Mutz (B63) 2013; 24 Magee (B56) 2014; 94 Nagalakshmi (B59) 2008; 320 Zhao (B94) 2014; 9 Coussens (B23) 2004; 72 Master (B84) 2008; 3 Berry (B51) 2013; 25 Schroder (B80) 2010; 140 Fang (B100) 2012; 2 Roy (B99) 2011; 10 McGettigan (B28) 2013; 17 Killick (B17) 2013; 15 Tessema (B14) 2001; 23 Molnar (B69) 2003; 1647 Dorhoi (B89) 2011; 240 Ather (B81) 2011; 187 Rajaram (B92) 2014; 26 Alleva (B74) 1997; 159 Dorhoi (B88) 2014; 26 Ozsolak (B62) 2011; 12 Arsenault (B76) 2012; 80 O’Garra (B91) 2013; 31 Liao (B36) 2013; 41 Hochreiter (B44) 2006; 22 Rue-Albrecht (B57) 2014; 5 Zimin (B35) 2009; 10 Davis (B3) 2012; 145 Talloen (B45) 2007; 23 Kabara (B25) 2012; 3 Olsen (B22) 2002; 24 Liao (B37) 2014; 30 23795683 - Cell Microbiol. 2013 Sep;15(9):1484-95 21851740 - Ir Vet J. 2009 Sep 01;62(9):597-606 23454067 - Dev Comp Immunol. 2013 Jun;40(2):210-7 11118712 - Vet Microbiol. 2000 Dec 20;77(3-4):269-81 22313120 - Crit Rev Microbiol. 2012 Aug;38(3):183-4 10727740 - Prev Vet Med. 2000 Mar 29;44(1-2):1-7 23260196 - Immunity. 2013 Jan 24;38(1):27-40 20132535 - Genome Biol. 2010;11(2):R14 24454679 - PLoS One. 2014 Jan 16;9(1):e78644 22737072 - PLoS Pathog. 2012;8(6):e1002769 18516045 - Nat Methods. 2008 Jul;5(7):621-8 19486308 - Transbound Emerg Dis. 2009 Aug;56(6-7):204-14 24130966 - Front Cell Infect Microbiol. 2013 Oct 09;3:62 22778093 - Infect Immun. 2012 Sep;80(9):3225-35 21389008 - Brief Funct Genomics. 2011 May;10(3):135-50 18984786 - Vet Pathol. 2008 Nov;45(6):829-41 15155609 - Infect Immun. 2004 Jun;72(6):3089-96 22689821 - Infect Immun. 2012 Sep;80(9):3039-48 23558742 - Nucleic Acids Res. 2013 May 1;41(10):e108 16473874 - Bioinformatics. 2006 Apr 15;22(8):943-9 9300718 - J Immunol. 1997 Sep 15;159(6):2941-51 22023831 - Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):525-35, v 15880345 - Arthritis Rheum. 2005 May;52(5):1402-10 22583818 - BMC Genomics. 2012 May 14;13:186 24098744 - PLoS One. 2013 Sep 30;8(9):e75924 23020966 - Curr Opin Biotechnol. 2013 Feb;24(1):22-30 21349097 - Immunol Rev. 2011 Mar;240(1):235-51 20444259 - BMC Genomics. 2010 May 05;11:282 22246630 - J Immunol. 2012 Feb 15;188(4):1992-2000 20495212 - Brief Funct Genomics. 2010 May;9(3):220-37 24112552 - BMC Genomics. 2013 Oct 10;14:694 17126540 - Curr Opin Immunol. 2007 Feb;19(1):10-6 18488015 - Nature. 2008 Jun 26;453(7199):1239-43 22285689 - Comp Immunol Microbiol Infect Dis. 2012 May;35(3):233-9 23940208 - Infect Immun. 2013 Nov;81(11):3960-5 17652449 - J Leukoc Biol. 2007 Oct;82(4):1011-8 21622869 - J Immunol. 2011 Jul 1;187(1):64-73 16478544 - BMC Microbiol. 2006 Feb 14;6:10 15461798 - Genome Biol. 2004;5(10):R80 19022505 - Vet Immunol Immunopathol. 2009 Mar 15;128(1-3):44-52 20439781 - Genetics. 2010 Jun;185(2):405-16 21451501 - Mucosal Immunol. 2011 May;4(3):261-70 25414700 - Front Immunol. 2014 Nov 05;5:536 25453226 - Semin Immunol. 2014 Dec;26(6):471-85 11765232 - Vet Q. 2001 Nov;23(4):153-62 25103872 - FEBS J. 2015 May;282(9):1768-73 12676127 - Comp Immunol Microbiol Infect Dis. 2003 Jul;26(4):269-83 22459833 - J Dairy Sci. 2012 Apr;95(4):1855-72 20303873 - Cell. 2010 Mar 19;140(6):821-32 25324841 - Front Immunol. 2014 Oct 01;5:422 22023832 - Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):537-46, v 23104886 - Bioinformatics. 2013 Jan 1;29(1):15-21 22209202 - Vet Immunol Immunopathol. 2012 Jan 15;145(1-2):1-6 22849430 - Cell Biosci. 2012 Jul 31;2(1):26 22211394 - J Vet Intern Med. 2012 Jan-Feb;26(1):32-45 23193258 - Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5 17389054 - Anim Health Res Rev. 2006 Jun-Dec;7(1-2):61-70 11118710 - Vet Microbiol. 2000 Dec 20;77(3-4):253-61 9050174 - Vet Rec. 1997 Feb 8;140(6):141-3 21047690 - Vet Immunol Immunopathol. 2010 Dec 15;138(4):303-11 21191423 - Nat Rev Genet. 2011 Feb;12(2):87-98 19617889 - Nat Protoc. 2009;4(8):1184-91 18599741 - Science. 2008 Aug 15;321(5891):956-60 21903743 - Genome Res. 2011 Dec;21(12):2213-23 24227677 - Bioinformatics. 2014 Apr 1;30(7):923-30 22455317 - Vet Res. 2012 Mar 28;43:25 19540774 - Semin Immunol. 2009 Oct;21(5):257-64 17921172 - Bioinformatics. 2007 Nov 1;23(21):2897-902 23516984 - Annu Rev Immunol. 2013;31:475-527 25453228 - Semin Immunol. 2014 Dec;26(6):533-42 12686136 - Biochim Biophys Acta. 2003 Apr 11;1647(1-2):220-4 21726990 - Curr Opin Immunol. 2011 Aug;23(4):464-72 22833736 - Front Microbiol. 2012 Jul 20;3:215 11118731 - Vet Microbiol. 2000 Dec 20;77(3-4):465-73 22384131 - PLoS One. 2012;7(2):e32034 20201007 - Eur J Immunol. 2010 Mar;40(3):595-8 22192698 - BMC Genomics. 2011 Dec 22;12:628 16646809 - Stat Appl Genet Mol Biol. 2004;3:Article3 11918176 - Vet Q. 2002 Feb;24(1):12-28 23160153 - Nat Immunol. 2013 Jan;14 (1):52-60 18064413 - Handb Exp Pharmacol. 2008;(184):107-27 21254832 - Crit Rev Microbiol. 2011 May;37(2):141-56 25157980 - Immunology. 2015 Feb;144(2):291-301 8828107 - Vet Clin North Am Food Anim Pract. 1996 Jul;12(2):305-12 22871324 - Int J Tuberc Lung Dis. 2012 Sep;16(9):1140-8 25206354 - Front Immunol. 2014 Aug 26;5:396 18451266 - Science. 2008 Jun 6;320(5881):1344-9 19393038 - Genome Biol. 2009;10(4):R42 19910308 - Bioinformatics. 2010 Jan 1;26(1):139-40 14573671 - Infect Immun. 2003 Nov;71(11):6487-98 21242003 - Vet Immunol Immunopathol. 2011 Mar 15;140(1-2):130-9 17467338 - Int J Med Microbiol. 2007 Nov;297(7-8):559-67 23565803 - BMC Genomics. 2013 Apr 08;14:230 18407066 - Cell Host Microbe. 2008 Apr 17;3(4):224-32 23290152 - Curr Opin Chem Biol. 2013 Feb;17(1):4-11 24021227 - Curr Opin Immunol. 2013 Oct;25(5):579-87 18550803 - Genome Res. 2008 Sep;18(9):1509-17 24882682 - Tuberculosis (Edinb). 2014 Jul;94(4):441-50 15900955 - Am J Vet Res. 2005 Apr;66(4):721-6 |
| References_xml | – volume: 26 start-page: 533 year: 2014 ident: B88 article-title: Perspectives on host adaptation in response to Mycobacterium tuberculosis: modulation of inflammation publication-title: Semin Immunol doi: 10.1016/j.smim.2014.10.002 – volume: 145 start-page: 1 year: 2012 ident: B3 article-title: Crohn’s disease and Mycobacterium avium subsp. paratuberculosis: the need for a study is long overdue publication-title: Vet Immunol Immunopathol doi: 10.1016/j.vetimm.2011.12.005 – volume: 62 start-page: 597 year: 2009 ident: B8 article-title: Prevalence and distribution of paratuberculosis (Johne’s disease) in cattle herds in Ireland publication-title: Ir Vet J doi: 10.1186/2046-0481-62-9-597 – volume: 71 start-page: 6487 year: 2003 ident: B64 article-title: Evidence for a novel gene expression program in peripheral blood mononuclear cells from Mycobacterium avium subsp. paratuberculosis-infected cattle publication-title: Infect Immun doi: 10.1128/IAI.71.11.6487-6498.2003 – volume: 41 start-page: e108 year: 2013 ident: B36 article-title: The subread aligner: fast, accurate and scalable read mapping by seed-and-vote publication-title: Nucleic Acids Res doi: 10.1093/nar/gkt214 – volume: 31 start-page: 475 year: 2013 ident: B91 article-title: The immune response in tuberculosis publication-title: Annu Rev Immunol doi: 10.1146/annurev-immunol-032712-095939 – volume: 3 start-page: 62 year: 2013 ident: B79 article-title: Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship publication-title: Front Cell Infect Microbiol doi: 10.3389/fcimb.2013.00062 – volume: 40 start-page: 595 year: 2010 ident: B78 article-title: NLR-containing inflammasomes: central mediators of host defense and inflammation publication-title: Eur J Immunol doi: 10.1002/eji.201040331 – volume: 23 start-page: 464 year: 2011 ident: B90 article-title: A delicate dance: host response to mycobacteria publication-title: Curr Opin Immunol doi: 10.1016/j.coi.2011.06.002 – volume: 8 start-page: e1002769 year: 2012 ident: B52 article-title: Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1002769 – volume: 184 start-page: 107 year: 2008 ident: B67 article-title: Core proteins of the secretory machinery publication-title: Handb Exp Pharmacol doi: 10.1007/978-3-540-74805-2_5 – volume: 38 start-page: 27 year: 2013 ident: B83 article-title: Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome publication-title: Immunity doi: 10.1016/j.immuni.2012.09.015 – volume: 24 start-page: 22 year: 2013 ident: B63 article-title: Transcriptome analysis using next-generation sequencing publication-title: Curr Opin Biotechnol doi: 10.1016/j.copbio.2012.09.004 – volume: 14 start-page: 52 year: 2013 ident: B85 article-title: Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta publication-title: Nat Immunol doi: 10.1038/ni.2474 – volume: 10 start-page: R42 year: 2009 ident: B35 article-title: A whole-genome assembly of the domestic cow, Bos taurus publication-title: Genome Biol doi: 10.1186/gb-2009-10-4-r42 – volume: 4 start-page: 1184 year: 2009 ident: B39 article-title: Mapping identifiers for the integration of genomic datasets with the R/bioconductor package biomaRt publication-title: Nat Protoc doi: 10.1038/nprot.2009.97 – volume: 13 start-page: 186 year: 2012 ident: B101 article-title: Estimating RNA-quality using GeneChip microarrays publication-title: BMC Genomics doi: 10.1186/1471-2164-13-186 – volume: 18 start-page: 1509 year: 2008 ident: B97 article-title: RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays publication-title: Genome Res doi: 10.1101/gr.079558.108 – volume: 7 start-page: 61 year: 2006 ident: B20 article-title: Host responses to Mycobacterium avium subsp. paratuberculosis: a complex arsenal publication-title: Anim Health Res Rev doi: 10.1017/s1466252307001168 – volume: 5 start-page: R80 year: 2004 ident: B43 article-title: Bioconductor: open software development for computational biology and bioinformatics publication-title: Genome Biol doi: 10.1186/gb-2004-5-10-r80 – volume: 25 start-page: 579 year: 2013 ident: B51 article-title: Systems approaches to studying the immune response in tuberculosis publication-title: Curr Opin Immunol doi: 10.1016/j.coi.2013.08.003 – volume: 188 start-page: 1992 year: 2012 ident: B82 article-title: Caspase-4 is required for activation of inflammasomes publication-title: J Immunol doi: 10.4049/jimmunol.1101620 – volume: 26 start-page: 269 year: 2003 ident: B68 article-title: Phagosomal maturation and intracellular survival of Mycobacterium avium subspecies paratuberculosis in J774 cells publication-title: Comp Immunol Microbiol Infect Dis doi: 10.1016/S0147-9571(02)00070-X – volume: 30 start-page: 923 year: 2014 ident: B37 article-title: featureCounts: an efficient general purpose program for assigning sequence reads to genomic features publication-title: Bioinformatics doi: 10.1093/bioinformatics/btt656 – volume: 35 start-page: 233 year: 2012 ident: B10 article-title: Regulatory T cells in cattle and their potential role in bovine paratuberculosis publication-title: Comp Immunol Microbiol Infect Dis doi: 10.1016/j.cimid.2012.01.004 – volume: 159 start-page: 2941 year: 1997 ident: B74 article-title: IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition publication-title: J Immunol doi: 10.4049/jimmunol.159.6.2941 – volume: 29 start-page: 15 year: 2013 ident: B34 article-title: STAR: ultrafast universal RNA-seq aligner publication-title: Bioinformatics doi: 10.1093/bioinformatics/bts635 – volume: 27 start-page: 537 year: 2011 ident: B21 article-title: Pathogenesis of paratuberculosis publication-title: Vet Clin North Am Food Anim Pract doi: 10.1016/j.cvfa.2011.07.001 – volume: 185 start-page: 405 year: 2010 ident: B95 article-title: Statistical design and analysis of RNA sequencing data publication-title: Genetics doi: 10.1534/genetics.110.114983 – volume: 140 start-page: 130 year: 2011 ident: B31 article-title: Transcriptional profiling of immune genes in bovine monocyte-derived macrophages exposed to bacterial antigens publication-title: Vet Immunol Immunopathol doi: 10.1016/j.vetimm.2010.12.002 – volume: 81 start-page: 3960 year: 2013 ident: B15 article-title: No holes barred: invasion of the intestinal mucosa by Mycobacterium avium subspecies paratuberculosis publication-title: Infect Immun doi: 10.1128/IAI.00575-13 – volume-title: Paratuberculosis: Organism, Disease, Control year: 2010 ident: B75 article-title: Host-pathogen interactions and intracellular survival of Mycobacterium avium subsp. paratuberculosis doi: 10.1079/9781845936136.0109 – volume: 26 start-page: 471 year: 2014 ident: B92 article-title: Macrophage immunoregulatory pathways in tuberculosis publication-title: Semin Immunol doi: 10.1016/j.smim.2014.09.010 – volume: 44 start-page: 1 year: 2000 ident: B7 article-title: Bulk-tank milk ELISA antibodies for estimating the prevalence of paratuberculosis in Danish dairy herds publication-title: Prev Vet Med doi: 10.1016/S0167-5877(00)00098-2 – volume: 5 start-page: 422 year: 2014 ident: B55 article-title: Key hub and bottleneck genes differentiate the macrophage response to virulent and attenuated Mycobacterium bovis publication-title: Front Immunol doi: 10.3389/fimmu.2014.00422 – volume: 80 start-page: 3039 year: 2012 ident: B76 article-title: Mycobacterium avium subsp. paratuberculosis inhibits gamma interferon-induced signaling in bovine monocytes: insights into the cellular mechanisms of Johne’s disease publication-title: Infect Immun doi: 10.1128/IAI.00406-12 – volume: 80 start-page: 3225 year: 2012 ident: B77 article-title: Infection with Mycobacterium avium subsp. paratuberculosis results in rapid interleukin-1beta release and macrophage transepithelial migration publication-title: Infect Immun doi: 10.1128/IAI.06322-11 – volume: 10 start-page: 135 year: 2011 ident: B99 article-title: A comparison of analog and next-generation transcriptomic tools for mammalian studies publication-title: Brief Funct Genomics doi: 10.1093/bfgp/elr005 – volume: 138 start-page: 303 year: 2010 ident: B49 article-title: Genomic and transcriptomic studies in Mycobacterium avium subspecies paratuberculosis publication-title: Vet Immunol Immunopathol doi: 10.1016/j.vetimm.2010.10.008 – volume: 3 start-page: 224 year: 2008 ident: B84 article-title: Mycobacterium tuberculosis prevents inflammasome activation publication-title: Cell Host Microbe doi: 10.1016/j.chom.2008.03.003 – volume: 12 start-page: 305 year: 1996 ident: B11 article-title: Transmission of paratuberculosis publication-title: Vet Clin North Am Food Anim Pract doi: 10.1016/S0749-0720(15)30408-4 – volume: 5 start-page: 621 year: 2008 ident: B58 article-title: Mapping and quantifying mammalian transcriptomes by RNA-Seq publication-title: Nat Methods doi: 10.1038/nmeth.1226 – volume: 240 start-page: 235 year: 2011 ident: B89 article-title: For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection publication-title: Immunol Rev doi: 10.1111/j.1600-065X.2010.00994.x – volume: 140 start-page: 821 year: 2010 ident: B80 article-title: The inflammasomes publication-title: Cell doi: 10.1016/j.cell.2010.01.040 – volume: 320 start-page: 1344 year: 2008 ident: B59 article-title: The transcriptional landscape of the yeast genome defined by RNA sequencing publication-title: Science doi: 10.1126/science.1158441 – volume: 38 start-page: 183 year: 2012 ident: B4 article-title: A commentary on current perspectives on Mycobacterium avium subsp. paratuberculosis, Johne’s disease and Crohn’s disease: a review by Over et al. (2011) publication-title: Crit Rev Microbiol doi: 10.3109/1040841x.2011.649712 – volume: 15 start-page: 1484 year: 2013 ident: B17 article-title: Receptor-mediated recognition of mycobacterial pathogens publication-title: Cell Microbiol doi: 10.1111/cmi.12161 – volume: 5 start-page: 396 year: 2014 ident: B33 article-title: RNA-seq transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis publication-title: Front Immunol doi: 10.3389/fimmu.2014.00396 – volume: 12 start-page: 87 year: 2011 ident: B62 article-title: RNA sequencing: advances, challenges and opportunities publication-title: Nat Rev Genet doi: 10.1038/nrg2934 – volume: 94 start-page: 441 year: 2014 ident: B56 article-title: Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection publication-title: Tuberculosis (Edinb) doi: 10.1016/j.tube.2014.04.004 – volume: 77 start-page: 269 year: 2000 ident: B5 article-title: Prevalence of paratuberculosis (Johne’s disease) in the Belgian cattle population publication-title: Vet Microbiol doi: 10.1016/S0378-1135(00)00312-6 – volume: 43 start-page: 25 year: 2012 ident: B30 article-title: Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis publication-title: Vet Res doi: 10.1186/1297-9716-43-25 – volume: 140 start-page: 141 year: 1997 ident: B1 article-title: Paratuberculosis in wild rabbits (Oryctolagus cuniculus) publication-title: Vet Rec doi: 10.1136/vr.140.6.141 – volume: 45 start-page: 829 year: 2008 ident: B24 article-title: Review paper: modulation of mononuclear phagocyte function by Mycobacterium avium subsp. paratuberculosis publication-title: Vet Pathol doi: 10.1354/vp.45-6-829 – volume: 27 start-page: 525 year: 2011 ident: B12 article-title: Epidemiology and economics of paratuberculosis publication-title: Vet Clin North Am Food Anim Pract doi: 10.1016/j.cvfa.2011.07.012 – volume: 4 start-page: 261 year: 2011 ident: B87 article-title: The role of IL-10 in immune regulation during M. tuberculosis infection publication-title: Mucosal Immunol doi: 10.1038/mi.2011.7 – volume: 26 start-page: 32 year: 2012 ident: B27 article-title: Risk factors associated with transmission of Mycobacterium avium subsp. paratuberculosis to calves within dairy herd: a systematic review publication-title: J Vet Intern Med doi: 10.1111/j.1939-1676.2011.00854.x – volume: 3 start-page: 215 year: 2012 ident: B25 article-title: Infection of primary bovine macrophages with Mycobacterium avium subspecies paratuberculosis suppresses host cell apoptosis publication-title: Front Microbiol doi: 10.3389/fmicb.2012.00215 – volume: 128 start-page: 44 year: 2009 ident: B72 article-title: Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and iNOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages publication-title: Vet Immunol Immunopathol doi: 10.1016/j.vetimm.2008.10.294 – volume: 453 start-page: 1239 year: 2008 ident: B61 article-title: Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution publication-title: Nature doi: 10.1038/nature07002 – volume: 77 start-page: 253 year: 2000 ident: B6 article-title: Prevalence and regional distribution of paratuberculosis in dairy herds in the Netherlands publication-title: Vet Microbiol doi: 10.1016/S0378-1135(00)00310-2 – volume: 2 start-page: 26 year: 2012 ident: B100 article-title: Statistical methods for identifying differentially expressed genes in RNA-Seq experiments publication-title: Cell Biosci doi: 10.1186/2045-3701-2-26 – volume: 144 start-page: 291 year: 2015 ident: B54 article-title: Microarray analysis of Mycobacterium tuberculosis-infected monocytes reveals IL-26 as a new candidate gene for tuberculosis susceptibility publication-title: Immunology doi: 10.1111/imm.12371 – volume: 9 start-page: 220 year: 2010 ident: B65 article-title: A large-scale study of differential gene expression in monocyte-derived macrophages infected with several strains of Mycobacterium avium subspecies paratuberculosis publication-title: Brief Funct Genomics doi: 10.1093/bfgp/elq009 – volume: 23 start-page: 153 year: 2001 ident: B14 article-title: How does Mycobacterium avium subsp. paratuberculosis resist intracellular degradation? publication-title: Vet Q doi: 10.1080/01652176.2001.9695105 – volume: 95 start-page: 1855 year: 2012 ident: B9 article-title: Economic analysis of Mycobacterium avium subspecies paratuberculosis vaccines in dairy herds publication-title: J Dairy Sci doi: 10.3168/jds.2011-4787 – volume: 16 start-page: 1140 year: 2012 ident: B50 article-title: Enabling biomarkers for tuberculosis control publication-title: Int J Tuberc Lung Dis doi: 10.5588/ijtld.12.0246 – volume: 3 start-page: Article3 year: 2004 ident: B46 article-title: Linear models and empirical bayes methods for assessing differential expression in microarray experiments publication-title: Stat Appl Genet Mol Biol doi: 10.2202/1544-6115.1027 – volume: 52 start-page: 1402 year: 2005 ident: B71 article-title: Kappa and delta opioid receptors are expressed but down-regulated in fibroblast-like synoviocytes of patients with rheumatoid arthritis and osteoarthritis publication-title: Arthritis Rheum doi: 10.1002/art.21141 – volume: 66 start-page: 721 year: 2005 ident: B86 article-title: A critical role of interleukin-10 in the response of bovine macrophages to infection by Mycobacterium avium subsp paratuberculosis publication-title: Am J Vet Res doi: 10.2460/ajvr.2005.66.721 – volume: 77 start-page: 465 year: 2000 ident: B13 article-title: Transitions in immune responses to Mycobacterium paratuberculosis publication-title: Vet Microbiol doi: 10.1016/S0378-1135(00)00331-X – year: 2014 ident: B70 article-title: A new role for LOX and LOXL2 proteins in transcription regulation publication-title: FEBS J doi: 10.1111/febs.12961 – volume: 82 start-page: 1011 year: 2007 ident: B18 article-title: Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2 publication-title: J Leukoc Biol doi: 10.1189/jlb.0307147 – volume: 17 start-page: 4 year: 2013 ident: B28 article-title: Transcriptomics in the RNA-seq era publication-title: Curr Opin Chem Biol doi: 10.1016/j.cbpa.2012.12.008 – volume: 22 start-page: 943 year: 2006 ident: B44 article-title: A new summarization method for Affymetrix probe level data publication-title: Bioinformatics doi: 10.1093/bioinformatics/btl033 – volume: 297 start-page: 559 year: 2007 ident: B47 article-title: Exploring functional genomics for the development of novel intervention strategies against tuberculosis publication-title: Int J Med Microbiol doi: 10.1016/j.ijmm.2007.03.003 – volume: 187 start-page: 64 year: 2011 ident: B81 article-title: Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice publication-title: J Immunol doi: 10.4049/jimmunol.1100500 – volume: 5 start-page: 536 year: 2014 ident: B57 article-title: Comparative functional genomics and the bovine macrophage response to strains of the Mycobacterium genus publication-title: Front Immunol doi: 10.3389/fimmu.2014.00536 – volume: 11 start-page: 282 year: 2010 ident: B98 article-title: A comparison of massively parallel nucleotide sequencing with oligonucleotide microarrays for global transcription profiling publication-title: BMC Genomics doi: 10.1186/1471-2164-11-282 – volume: 21 start-page: 2213 year: 2011 ident: B96 article-title: Differential expression in RNA-seq: a matter of depth publication-title: Genome Res doi: 10.1101/gr.124321.111 – volume: 8 start-page: e75924 year: 2013 ident: B26 article-title: Mannosylated lipoarabinomannans from Mycobacterium avium subsp. paratuberculosis alters the inflammatory response by bovine macrophages and suppresses killing of Mycobacterium avium subsp. avium organisms publication-title: PLoS One doi: 10.1371/journal.pone.0075924 – volume: 1647 start-page: 220 year: 2003 ident: B69 article-title: Structural and functional diversity of lysyl oxidase and the LOX-like proteins publication-title: Biochim Biophys Acta doi: 10.1016/S1570-9639(03)00053-0 – volume: 14 start-page: 694 year: 2013 ident: B53 article-title: Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection publication-title: BMC Genomics doi: 10.1186/1471-2164-14-694 – volume: 24 start-page: 12 year: 2002 ident: B22 article-title: Paratuberculosis with special reference to cattle. A review publication-title: Vet Q doi: 10.1080/01652176.2002.9695120 – volume: 7 start-page: e32034 year: 2012 ident: B32 article-title: Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis publication-title: PLoS One doi: 10.1371/journal.pone.0032034 – volume: 9 start-page: e78644 year: 2014 ident: B94 article-title: Comparison of RNA-Seq and microarray in transcriptome profiling of activated T cells publication-title: PLoS One doi: 10.1371/journal.pone.0078644 – volume: 72 start-page: 3089 year: 2004 ident: B23 article-title: Model for immune responses to Mycobacterium avium subspecies paratuberculosis in cattle publication-title: Infect Immun doi: 10.1128/iai.72.6.3089-3096.2004 – volume: 21 start-page: 257 year: 2009 ident: B73 article-title: Macrophage CD40 signaling: a pivotal regulator of disease protection and pathogenesis publication-title: Semin Immunol doi: 10.1016/j.smim.2009.05.011 – volume: 41 start-page: D991 year: 2013 ident: B42 article-title: NCBI GEO: archive for functional genomics data sets – update publication-title: Nucleic Acids Res doi: 10.1093/nar/gks1193 – volume: 26 start-page: 139 year: 2010 ident: B38 article-title: edgeR: a Bioconductor package for differential expression analysis of digital gene expression data publication-title: Bioinformatics doi: 10.1093/bioinformatics/btp616 – volume: 6 start-page: 10 year: 2006 ident: B19 article-title: Cytokine responses of bovine macrophages to diverse clinical Mycobacterium avium subspecies paratuberculosis strains publication-title: BMC Microbiol doi: 10.1186/1471-2180-6-10 – volume: 23 start-page: 2897 year: 2007 ident: B45 article-title: I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data publication-title: Bioinformatics doi: 10.1093/bioinformatics/btm478 – volume: 321 start-page: 956 year: 2008 ident: B60 article-title: A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome publication-title: Science doi: 10.1126/science.1160342 – volume: 57 start-page: 289 year: 1995 ident: B40 article-title: Controlling the false discovery rate – a practical and powerful approach to multiple testing publication-title: J R Stat Soc Ser B Methodol doi: 10.1111/j.2517-6161.1995.tb02031.x – volume: 19 start-page: 10 year: 2007 ident: B16 article-title: Innate recognition of intracellular bacteria publication-title: Curr Opin Immunol doi: 10.1016/j.coi.2006.11.005 – volume: 11 start-page: R14 year: 2010 ident: B41 article-title: Gene ontology analysis for RNA-seq: accounting for selection bias publication-title: Genome Biol doi: 10.1186/gb-2010-11-2-r14 – volume: 37 start-page: 141 year: 2011 ident: B2 article-title: Current perspectives on Mycobacterium avium subsp. paratuberculosis, Johne’s disease, and Crohn’s disease: a review publication-title: Crit Rev Microbiol doi: 10.3109/1040841x.2010.532480 – volume: 14 start-page: 230 year: 2013 ident: B29 article-title: Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro publication-title: BMC Genomics doi: 10.1186/1471-2164-14-230 – volume: 40 start-page: 210 year: 2013 ident: B66 article-title: Global gene expression profiling of monocyte-derived macrophages from red deer (Cervus elaphus) genotypically resistant or susceptible to Mycobacterium avium subspecies paratuberculosis infection publication-title: Dev Comp Immunol doi: 10.1016/j.dci.2013.02.004 – volume: 12 start-page: 628 year: 2011 ident: B93 article-title: Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis publication-title: BMC Genomics doi: 10.1186/1471-2164-12-628 – volume: 56 start-page: 204 year: 2009 ident: B48 article-title: Gene expression profiling of the host response to Mycobacterium bovis infection in cattle publication-title: Transbound Emerg Dis doi: 10.1111/j.1865-1682.2009.01082.x – reference: 15461798 - Genome Biol. 2004;5(10):R80 – reference: 18599741 - Science. 2008 Aug 15;321(5891):956-60 – reference: 21254832 - Crit Rev Microbiol. 2011 May;37(2):141-56 – reference: 9050174 - Vet Rec. 1997 Feb 8;140(6):141-3 – reference: 22211394 - J Vet Intern Med. 2012 Jan-Feb;26(1):32-45 – reference: 18407066 - Cell Host Microbe. 2008 Apr 17;3(4):224-32 – reference: 17921172 - Bioinformatics. 2007 Nov 1;23(21):2897-902 – reference: 17389054 - Anim Health Res Rev. 2006 Jun-Dec;7(1-2):61-70 – reference: 17467338 - Int J Med Microbiol. 2007 Nov;297(7-8):559-67 – reference: 24882682 - Tuberculosis (Edinb). 2014 Jul;94(4):441-50 – reference: 23454067 - Dev Comp Immunol. 2013 Jun;40(2):210-7 – reference: 17652449 - J Leukoc Biol. 2007 Oct;82(4):1011-8 – reference: 21349097 - Immunol Rev. 2011 Mar;240(1):235-51 – reference: 25453226 - Semin Immunol. 2014 Dec;26(6):471-85 – reference: 16473874 - Bioinformatics. 2006 Apr 15;22(8):943-9 – reference: 23260196 - Immunity. 2013 Jan 24;38(1):27-40 – reference: 20439781 - Genetics. 2010 Jun;185(2):405-16 – reference: 11918176 - Vet Q. 2002 Feb;24(1):12-28 – reference: 25324841 - Front Immunol. 2014 Oct 01;5:422 – reference: 22246630 - J Immunol. 2012 Feb 15;188(4):1992-2000 – reference: 23565803 - BMC Genomics. 2013 Apr 08;14:230 – reference: 23020966 - Curr Opin Biotechnol. 2013 Feb;24(1):22-30 – reference: 19393038 - Genome Biol. 2009;10(4):R42 – reference: 23940208 - Infect Immun. 2013 Nov;81(11):3960-5 – reference: 24227677 - Bioinformatics. 2014 Apr 1;30(7):923-30 – reference: 22384131 - PLoS One. 2012;7(2):e32034 – reference: 18064413 - Handb Exp Pharmacol. 2008;(184):107-27 – reference: 11118731 - Vet Microbiol. 2000 Dec 20;77(3-4):465-73 – reference: 25453228 - Semin Immunol. 2014 Dec;26(6):533-42 – reference: 15155609 - Infect Immun. 2004 Jun;72(6):3089-96 – reference: 11765232 - Vet Q. 2001 Nov;23(4):153-62 – reference: 22583818 - BMC Genomics. 2012 May 14;13:186 – reference: 22209202 - Vet Immunol Immunopathol. 2012 Jan 15;145(1-2):1-6 – reference: 23795683 - Cell Microbiol. 2013 Sep;15(9):1484-95 – reference: 18984786 - Vet Pathol. 2008 Nov;45(6):829-41 – reference: 18488015 - Nature. 2008 Jun 26;453(7199):1239-43 – reference: 23160153 - Nat Immunol. 2013 Jan;14 (1):52-60 – reference: 21451501 - Mucosal Immunol. 2011 May;4(3):261-70 – reference: 20495212 - Brief Funct Genomics. 2010 May;9(3):220-37 – reference: 22023831 - Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):525-35, v – reference: 16646809 - Stat Appl Genet Mol Biol. 2004;3:Article3 – reference: 21389008 - Brief Funct Genomics. 2011 May;10(3):135-50 – reference: 22023832 - Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):537-46, v – reference: 20444259 - BMC Genomics. 2010 May 05;11:282 – reference: 12686136 - Biochim Biophys Acta. 2003 Apr 11;1647(1-2):220-4 – reference: 9300718 - J Immunol. 1997 Sep 15;159(6):2941-51 – reference: 22285689 - Comp Immunol Microbiol Infect Dis. 2012 May;35(3):233-9 – reference: 24021227 - Curr Opin Immunol. 2013 Oct;25(5):579-87 – reference: 25206354 - Front Immunol. 2014 Aug 26;5:396 – reference: 14573671 - Infect Immun. 2003 Nov;71(11):6487-98 – reference: 17126540 - Curr Opin Immunol. 2007 Feb;19(1):10-6 – reference: 24130966 - Front Cell Infect Microbiol. 2013 Oct 09;3:62 – reference: 11118712 - Vet Microbiol. 2000 Dec 20;77(3-4):269-81 – reference: 22313120 - Crit Rev Microbiol. 2012 Aug;38(3):183-4 – reference: 20132535 - Genome Biol. 2010;11(2):R14 – reference: 23290152 - Curr Opin Chem Biol. 2013 Feb;17(1):4-11 – reference: 22849430 - Cell Biosci. 2012 Jul 31;2(1):26 – reference: 22737072 - PLoS Pathog. 2012;8(6):e1002769 – reference: 18516045 - Nat Methods. 2008 Jul;5(7):621-8 – reference: 22455317 - Vet Res. 2012 Mar 28;43:25 – reference: 24098744 - PLoS One. 2013 Sep 30;8(9):e75924 – reference: 23558742 - Nucleic Acids Res. 2013 May 1;41(10):e108 – reference: 19910308 - Bioinformatics. 2010 Jan 1;26(1):139-40 – reference: 21903743 - Genome Res. 2011 Dec;21(12):2213-23 – reference: 21851740 - Ir Vet J. 2009 Sep 01;62(9):597-606 – reference: 19022505 - Vet Immunol Immunopathol. 2009 Mar 15;128(1-3):44-52 – reference: 23104886 - Bioinformatics. 2013 Jan 1;29(1):15-21 – reference: 22689821 - Infect Immun. 2012 Sep;80(9):3039-48 – reference: 21622869 - J Immunol. 2011 Jul 1;187(1):64-73 – reference: 18451266 - Science. 2008 Jun 6;320(5881):1344-9 – reference: 12676127 - Comp Immunol Microbiol Infect Dis. 2003 Jul;26(4):269-83 – reference: 11118710 - Vet Microbiol. 2000 Dec 20;77(3-4):253-61 – reference: 15900955 - Am J Vet Res. 2005 Apr;66(4):721-6 – reference: 22778093 - Infect Immun. 2012 Sep;80(9):3225-35 – reference: 8828107 - Vet Clin North Am Food Anim Pract. 1996 Jul;12(2):305-12 – reference: 23516984 - Annu Rev Immunol. 2013;31:475-527 – reference: 20201007 - Eur J Immunol. 2010 Mar;40(3):595-8 – reference: 22833736 - Front Microbiol. 2012 Jul 20;3:215 – reference: 21047690 - Vet Immunol Immunopathol. 2010 Dec 15;138(4):303-11 – reference: 21191423 - Nat Rev Genet. 2011 Feb;12(2):87-98 – reference: 23193258 - Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5 – reference: 25103872 - FEBS J. 2015 May;282(9):1768-73 – reference: 10727740 - Prev Vet Med. 2000 Mar 29;44(1-2):1-7 – reference: 16478544 - BMC Microbiol. 2006 Feb 14;6:10 – reference: 24454679 - PLoS One. 2014 Jan 16;9(1):e78644 – reference: 19540774 - Semin Immunol. 2009 Oct;21(5):257-64 – reference: 22871324 - Int J Tuberc Lung Dis. 2012 Sep;16(9):1140-8 – reference: 22459833 - J Dairy Sci. 2012 Apr;95(4):1855-72 – reference: 18550803 - Genome Res. 2008 Sep;18(9):1509-17 – reference: 20303873 - Cell. 2010 Mar 19;140(6):821-32 – reference: 21726990 - Curr Opin Immunol. 2011 Aug;23(4):464-72 – reference: 25157980 - Immunology. 2015 Feb;144(2):291-301 – reference: 25414700 - Front Immunol. 2014 Nov 05;5:536 – reference: 22192698 - BMC Genomics. 2011 Dec 22;12:628 – reference: 19486308 - Transbound Emerg Dis. 2009 Aug;56(6-7):204-14 – reference: 15880345 - Arthritis Rheum. 2005 May;52(5):1402-10 – reference: 21242003 - Vet Immunol Immunopathol. 2011 Mar 15;140(1-2):130-9 – reference: 24112552 - BMC Genomics. 2013 Oct 10;14:694 – reference: 19617889 - Nat Protoc. 2009;4(8):1184-91 |
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| Title | Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq |
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