Treated HIV Infection Alters Phenotype but Not HIV-Specific Function of Peripheral Blood Natural Killer Cells

Natural killer (NK) cells are the predominant antiviral cells of the innate immune system, and may play an important role in acquisition and disease progression of HIV. While untreated HIV infection is associated with distinct alterations in the peripheral blood NK cell repertoire, less is known abo...

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Veröffentlicht in:	Frontiers in immunology Jg. 11; S. 829
Hauptverfasser:	Zhao, Nancy Q., Ferreira, Anne-Maud, Grant, Philip M., Holmes, Susan, Blish, Catherine A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 12.05.2020
Schlagworte:	Adult Aged Anti-HIV Agents - therapeutic use CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - virology Cells, Cultured Coculture Techniques Cohort Studies CyTOF Female HIV Infections - blood HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 HIV-1 - immunology Humans Immunology innate immunity Interleukin-2 - genetics Interleukin-2 - therapeutic use Killer Cells, Natural - immunology Male memory Middle Aged NK cells Phenotype Receptors, Natural Killer Cell - metabolism Recombinant Proteins - therapeutic use Treatment Outcome HIV-1 NK cells memory innate immunity CyTOF
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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