Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

The analysis of phenotypic characteristics on (MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) and for monitoring treatment success. We therefore studied phenotypic changes on MTB-specific CD4 T cells upon anti-tuberculosis treatment initiation in relatio...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 9; p. 2247
Main Authors:	Ahmed, Mohamed I. M., Ntinginya, Nyanda E., Kibiki, Gibson, Mtafya, Bariki A, Semvua, Hadija, Mpagama, Stellah, Mtabho, Charles, Saathoff, Elmar, Held, Kathrin, Loose, Rebecca, Kroidl, Inge, Chachage, Mkunde, Both, Ulrich von, Haule, Antelmo, Mekota, Anna-Maria, Boeree, Martin J., Gillespie, Stephen H., Hoelscher, Michael, Heinrich, Norbert, Geldmacher, Christof
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 28.09.2018
Subjects:	biomarker Immunology Mycobacterium tuberculosis-specific T cells serial sputum culture TAM-TB assay treatment monitoring tuberculosis TAM-TB assay biomarker treatment monitoring Mycobacterium tuberculosis-specific T cells tuberculosis serial sputum culture
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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