Incidence of Tuberculosis in Inflammatory Rheumatic Diseases: Results from a Lithuanian Retrospective Cohort Study
Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special a...
Gespeichert in:
| Veröffentlicht in: | Medicina (Kaunas, Lithuania) Jg. 56; H. 8; S. 392 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Switzerland
MDPI
05.08.2020
MDPI AG |
| Schlagworte: | |
| ISSN: | 1648-9144, 1010-660X, 1648-9144 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special attention in patients with rheumatic diseases (RD). Although Lithuanian population has one of the highest TB incidence rates among European countries, the incidence of TB in the rheumatic patients’ population is still unknown. The aim of this study was to assess the incidence rate of TB in an inflammatory RD retrospective cohort and to compare that rate with a rate in a general population. Material and Methods: Patients with the first-time diagnosis of inflammatory RD during the period between 1 January 2012 and 31 December 2017 were identified from the Lithuanian Compulsory Health Insurance Information System database SVEIDRA. All cases were cross-checked with Health Information center at the Institute of Hygiene, for the vital status of these patients and date of death if the fact of death was documented, and with Tuberculosis Register operated by Vilnius University Hospital Santaros Klinikos, for the confirmation of TB cases. Sex and age standardized incidence ratios (SIR) were calculated by dividing the observed numbers of TB among rheumatic patients by the expected number of cases, calculated using national rates from Lithuanian Department of Statistics Official Statistics website. Results: Overall, 8779 patients with newly diagnosed RD were identified during the 2013–2017 period, these included 458 patients who used biological disease modifying drugs (bDMARDs). The mean duration of the follow-up period was 2.71 years. The cohort consisted mainly of women (70%) and a half of the cohort were rheumatoid arthritis (RA) patients (53%). Mean age of patients at the time of RD diagnosis was 56 years (range = 18–97 years). There were 9 TB cases identified during 23,800 person years of follow-up: 2 cases among them were treated with bDMARDs. The mean calculated annual TB incidence in RD cohort was 37.81 per 100,000 person years, which is consistent with the incidence rate predicted by national estimates, with a resultant SIR of 0.90 (0.41–1.70). The unadjusted hazard ratio for bDMARD use versus no bDMARD use was 4.54 (0.94; 21.87) in a total cohort and very similar in rheumatoid arthritis cohort; in both cohorts, it was not a statistically significant risk. Conclusions: Here, we present the first nationwide cohort study to assess the incidence of TB in a broad spectrum of inflammatory RD. Although limited by short follow-up period, this study shows that TB incidence in RD cohort does not exceed TB incidence in the general Lithuanian population. |
|---|---|
| AbstractList | With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special attention in patients with rheumatic diseases (RD). Although Lithuanian population has one of the highest TB incidence rates among European countries, the incidence of TB in the rheumatic patients' population is still unknown. The aim of this study was to assess the incidence rate of TB in an inflammatory RD retrospective cohort and to compare that rate with a rate in a general population.
Patients with the first-time diagnosis of inflammatory RD during the period between 1 January 2012 and 31 December 2017 were identified from the Lithuanian Compulsory Health Insurance Information System database SVEIDRA. All cases were cross-checked with Health Information center at the Institute of Hygiene, for the vital status of these patients and date of death if the fact of death was documented, and with Tuberculosis Register operated by Vilnius University Hospital Santaros Klinikos, for the confirmation of TB cases. Sex and age standardized incidence ratios (SIR) were calculated by dividing the observed numbers of TB among rheumatic patients by the expected number of cases, calculated using national rates from Lithuanian Department of Statistics Official Statistics website.
Overall, 8779 patients with newly diagnosed RD were identified during the 2013-2017 period, these included 458 patients who used biological disease modifying drugs (bDMARDs). The mean duration of the follow-up period was 2.71 years. The cohort consisted mainly of women (70%) and a half of the cohort were rheumatoid arthritis (RA) patients (53%). Mean age of patients at the time of RD diagnosis was 56 years (range = 18-97 years). There were 9 TB cases identified during 23,800 person years of follow-up: 2 cases among them were treated with bDMARDs. The mean calculated annual TB incidence in RD cohort was 37.81 per 100,000 person years, which is consistent with the incidence rate predicted by national estimates, with a resultant SIR of 0.90 (0.41-1.70). The unadjusted hazard ratio for bDMARD use versus no bDMARD use was 4.54 (0.94; 21.87) in a total cohort and very similar in rheumatoid arthritis cohort; in both cohorts, it was not a statistically significant risk.
Here, we present the first nationwide cohort study to assess the incidence of TB in a broad spectrum of inflammatory RD. Although limited by short follow-up period, this study shows that TB incidence in RD cohort does not exceed TB incidence in the general Lithuanian population. Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special attention in patients with rheumatic diseases (RD). Although Lithuanian population has one of the highest TB incidence rates among European countries, the incidence of TB in the rheumatic patients’ population is still unknown. The aim of this study was to assess the incidence rate of TB in an inflammatory RD retrospective cohort and to compare that rate with a rate in a general population. Material and Methods: Patients with the first-time diagnosis of inflammatory RD during the period between 1 January 2012 and 31 December 2017 were identified from the Lithuanian Compulsory Health Insurance Information System database SVEIDRA. All cases were cross-checked with Health Information center at the Institute of Hygiene, for the vital status of these patients and date of death if the fact of death was documented, and with Tuberculosis Register operated by Vilnius University Hospital Santaros Klinikos, for the confirmation of TB cases. Sex and age standardized incidence ratios (SIR) were calculated by dividing the observed numbers of TB among rheumatic patients by the expected number of cases, calculated using national rates from Lithuanian Department of Statistics Official Statistics website. Results: Overall, 8779 patients with newly diagnosed RD were identified during the 2013–2017 period, these included 458 patients who used biological disease modifying drugs (bDMARDs). The mean duration of the follow-up period was 2.71 years. The cohort consisted mainly of women (70%) and a half of the cohort were rheumatoid arthritis (RA) patients (53%). Mean age of patients at the time of RD diagnosis was 56 years (range = 18–97 years). There were 9 TB cases identified during 23,800 person years of follow-up: 2 cases among them were treated with bDMARDs. The mean calculated annual TB incidence in RD cohort was 37.81 per 100,000 person years, which is consistent with the incidence rate predicted by national estimates, with a resultant SIR of 0.90 (0.41–1.70). The unadjusted hazard ratio for bDMARD use versus no bDMARD use was 4.54 (0.94; 21.87) in a total cohort and very similar in rheumatoid arthritis cohort; in both cohorts, it was not a statistically significant risk. Conclusions: Here, we present the first nationwide cohort study to assess the incidence of TB in a broad spectrum of inflammatory RD. Although limited by short follow-up period, this study shows that TB incidence in RD cohort does not exceed TB incidence in the general Lithuanian population. Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special attention in patients with rheumatic diseases (RD). Although Lithuanian population has one of the highest TB incidence rates among European countries, the incidence of TB in the rheumatic patients' population is still unknown. The aim of this study was to assess the incidence rate of TB in an inflammatory RD retrospective cohort and to compare that rate with a rate in a general population. Methods: Patients with the first-time diagnosis of inflammatory RD during the period between 1 January 2012 and 31 December 2017 were identified from the Lithuanian Compulsory Health Insurance Information System database SVEIDRA. All cases were cross-checked with Health Information center at the Institute of Hygiene, for the vital status of these patients and date of death if the fact of death was documented, and with Tuberculosis Register operated by Vilnius University Hospital Santaros Klinikos, for the confirmation of TB cases. Sex and age standardized incidence ratios (SIR) were calculated by dividing the observed numbers of TB among rheumatic patients by the expected number of cases, calculated using national rates from Lithuanian Department of Statistics Official Statistics website. Results: Overall, 8779 patients with newly diagnosed RD were identified during the 2013-2017 period, these included 458 patients who used biological disease modifying drugs (bDMARDs). The mean duration of the follow-up period was 2.71 years. The cohort consisted mainly of women (70%) and a half of the cohort were rheumatoid arthritis (RA) patients (53%). Mean age of patients at the time of RD diagnosis was 56 years (range = 18-97 years). There were 9 TB cases identified during 23,800 person years of follow-up: 2 cases among them were treated with bDMARDs. The mean calculated annual TB incidence in RD cohort was 37.81 per 100,000 person years, which is consistent with the incidence rate predicted by national estimates, with a resultant SIR of 0.90 (0.41-1.70). The unadjusted hazard ratio for bDMARD use versus no bDMARD use was 4.54 (0.94; 21.87) in a total cohort and very similar in rheumatoid arthritis cohort; in both cohorts, it was not a statistically significant risk. Conclusions: Here, we present the first nationwide cohort study to assess the incidence of TB in a broad spectrum of inflammatory RD. Although limited by short follow-up period, this study shows that TB incidence in RD cohort does not exceed TB incidence in the general Lithuanian population.Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the introduction of biologicals to the treatment algorithms. Tuberculosis (TB) infection has always been given a special attention in patients with rheumatic diseases (RD). Although Lithuanian population has one of the highest TB incidence rates among European countries, the incidence of TB in the rheumatic patients' population is still unknown. The aim of this study was to assess the incidence rate of TB in an inflammatory RD retrospective cohort and to compare that rate with a rate in a general population. Methods: Patients with the first-time diagnosis of inflammatory RD during the period between 1 January 2012 and 31 December 2017 were identified from the Lithuanian Compulsory Health Insurance Information System database SVEIDRA. All cases were cross-checked with Health Information center at the Institute of Hygiene, for the vital status of these patients and date of death if the fact of death was documented, and with Tuberculosis Register operated by Vilnius University Hospital Santaros Klinikos, for the confirmation of TB cases. Sex and age standardized incidence ratios (SIR) were calculated by dividing the observed numbers of TB among rheumatic patients by the expected number of cases, calculated using national rates from Lithuanian Department of Statistics Official Statistics website. Results: Overall, 8779 patients with newly diagnosed RD were identified during the 2013-2017 period, these included 458 patients who used biological disease modifying drugs (bDMARDs). The mean duration of the follow-up period was 2.71 years. The cohort consisted mainly of women (70%) and a half of the cohort were rheumatoid arthritis (RA) patients (53%). Mean age of patients at the time of RD diagnosis was 56 years (range = 18-97 years). There were 9 TB cases identified during 23,800 person years of follow-up: 2 cases among them were treated with bDMARDs. The mean calculated annual TB incidence in RD cohort was 37.81 per 100,000 person years, which is consistent with the incidence rate predicted by national estimates, with a resultant SIR of 0.90 (0.41-1.70). The unadjusted hazard ratio for bDMARD use versus no bDMARD use was 4.54 (0.94; 21.87) in a total cohort and very similar in rheumatoid arthritis cohort; in both cohorts, it was not a statistically significant risk. Conclusions: Here, we present the first nationwide cohort study to assess the incidence of TB in a broad spectrum of inflammatory RD. Although limited by short follow-up period, this study shows that TB incidence in RD cohort does not exceed TB incidence in the general Lithuanian population. |
| Author | Deresevičienė, Giedrė Danila, Edvardas Butrimienė, Irena Nakčerienė, Birutė Miltinienė, Dalia Davidavičienė, Valerija Edita Dadonienė, Jolanta |
| AuthorAffiliation | 1 State Research Institute Centre for Innovative Medicine, LT-08406 Vilnius, Lithuania; jolanta.dadoniene@mf.vu.lt 7 Institute of Clinical Medicine, Clinic of Chest Diseases, Immunology and Allergology, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania 6 Centre of Pulmonology and Allergology, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; edvardas.danila@santa.lt 3 Centre of Rheumatology, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; giedre.dereseviciene@santa.lt (G.D.); irena.butrimiene@santa.lt (I.B.) 4 Programs and Tuberculosis State Information System Department, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; bnakceriene@gmail.com (B.N.); edita.davidaviciene@santa.lt (V.E.D.) 2 Institute of Clinical Medicine, Clinic of Rheumatology, Orthopaedics Traumatology and Reconstructive Surgery, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania 5 Vilnius University Life Scien |
| AuthorAffiliation_xml | – name: 8 Institute of Health Sciences, Department of Public Health, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania – name: 3 Centre of Rheumatology, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; giedre.dereseviciene@santa.lt (G.D.); irena.butrimiene@santa.lt (I.B.) – name: 2 Institute of Clinical Medicine, Clinic of Rheumatology, Orthopaedics Traumatology and Reconstructive Surgery, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania – name: 1 State Research Institute Centre for Innovative Medicine, LT-08406 Vilnius, Lithuania; jolanta.dadoniene@mf.vu.lt – name: 5 Vilnius University Life Sciences Center, LT-10257 Vilnius, Lithuania – name: 4 Programs and Tuberculosis State Information System Department, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; bnakceriene@gmail.com (B.N.); edita.davidaviciene@santa.lt (V.E.D.) – name: 7 Institute of Clinical Medicine, Clinic of Chest Diseases, Immunology and Allergology, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania – name: 6 Centre of Pulmonology and Allergology, Vilnius University Hospital Santaros Klinikos, LT-08661 Vilnius, Lithuania; edvardas.danila@santa.lt |
| Author_xml | – sequence: 1 givenname: Dalia surname: Miltinienė fullname: Miltinienė, Dalia – sequence: 2 givenname: Giedrė surname: Deresevičienė fullname: Deresevičienė, Giedrė – sequence: 3 givenname: Birutė surname: Nakčerienė fullname: Nakčerienė, Birutė – sequence: 4 givenname: Valerija Edita surname: Davidavičienė fullname: Davidavičienė, Valerija Edita – sequence: 5 givenname: Edvardas surname: Danila fullname: Danila, Edvardas – sequence: 6 givenname: Irena surname: Butrimienė fullname: Butrimienė, Irena – sequence: 7 givenname: Jolanta surname: Dadonienė fullname: Dadonienė, Jolanta |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32764422$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kk1v1DAQhiPUin7AnRPykcuC7dhxwgEJLQVWWqlSKWdr4oy7rhJ7sZ1K--_xdkvVVuLkked9n7Fn5qw68sFjVb1j9GNdd_TThIMzzoNsaEvrjr-qTlkj2kXHhDh6Ep9UZyndUlpzqfjr6qTmqhGC89MqrrxxA3qDJFhyPfcYzTyG5BJxnqy8HWGaIIe4I1cbnEvoDPnmEkLC9JlcYZrHnIiNYSJA1i5vZvAOfMnkGNIWTXZ3SJZhE2Imv_I87N5UxxbGhG8fzvPq9_eL6-XPxfryx2r5db0wouF50RqBrUQwAKoHxkEC1hKtAkX5YKVgyBCktD2ynlo-AMV-aCWzbSeNhfq8Wh24Q4BbvY1ugrjTAZy-vwjxRkMs3xlRGwoda3upFLeCowEme25Yy7uGqX5QhfXlwNrOfWm6QZ8jjM-gzzPebfRNuNNKNE3N9oAPD4AY_syYsp5cMjiO4DHMSXNRs5YJVTdF-v5prcci_4ZWBPQgMKXDKaJ9lDCq93uhX-5FsTQvLMblMsuwf60b_2_8C-iiww0 |
| CitedBy_id | crossref_primary_10_3389_fpubh_2022_948652 crossref_primary_10_1016_j_ijtb_2023_07_001 |
| Cites_doi | 10.1007/BF01451043 10.1016/S0891-5520(05)70149-5 10.3899/jrheum.150057 10.1056/NEJMoa011110 10.3899/jrheum.090074 10.1136/annrheumdis-2013-204960 10.1002/art.24476 10.1016/j.ijantimicag.2007.07.010 10.1136/ard.2005.047274 10.1136/ard.61.3.251 10.1002/art.20009 10.1111/jcpt.12814 10.1016/j.jbspin.2010.12.004 10.1371/journal.pone.0178035 10.1183/09031936.00028510 10.1002/art.11137 10.1093/rap/rkz020 10.1164/ajrccm.158.2.9709125 10.1080/14740338.2016.1240783 10.1002/art.21083 10.1002/art.24632 10.1002/art.21137 10.1136/annrheumdis-2016-210708 10.1111/jcpt.12644 10.1016/S0140-6736(15)00151-8 10.1136/bmjopen-2016-012567 10.3390/medicina47030026 |
| ContentType | Journal Article |
| Copyright | 2020 by the authors. 2020 |
| Copyright_xml | – notice: 2020 by the authors. 2020 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM DOA |
| DOI | 10.3390/medicina56080392 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE CrossRef MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Open Access Full Text url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1648-9144 |
| ExternalDocumentID | oai_doaj_org_article_c0a918b5772f42eca15b2c1829617bd7 PMC7466317 32764422 10_3390_medicina56080392 |
| Genre | Journal Article |
| GeographicLocations | Lithuania |
| GeographicLocations_xml | – name: Lithuania |
| GroupedDBID | 0R~ 29M 2WC 4.4 457 53G 5GY 5VS 7X7 8FI 8FJ AADQD AAEDT AAFWJ AAIKJ AAYXX ABMAC ABUWG ACGFS ADBBV ADEZE AFFHD AFKRA AFPKN AFZYC AGHFR AHDRD ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BCNDV BENPR CCPQU CITATION F5P FDB FYUFA GROUPED_DOAJ HMCUK HYE IAO IHR KQ8 MODMG O9- OK1 OVT PGMZT PHGZM PHGZT PIMPY RPM UKHRP XSB AACTN ALIPV CGR CUY CVF ECM EIF NPM 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c462t-8c4e85eacaa7ba12a5ae35ef7a702df541e1ea55fbe1b0f2da0ebd851f895cfa3 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 1 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000564049300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1648-9144 1010-660X |
| IngestDate | Thu Oct 09 03:04:13 EDT 2025 Tue Nov 04 01:51:52 EST 2025 Fri Sep 05 10:54:39 EDT 2025 Thu Apr 03 06:56:12 EDT 2025 Tue Nov 18 20:41:44 EST 2025 Sat Nov 29 07:18:36 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 8 |
| Keywords | incidence rheumatic diseases tuberculosis |
| Language | English |
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c462t-8c4e85eacaa7ba12a5ae35ef7a702df541e1ea55fbe1b0f2da0ebd851f895cfa3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://doaj.org/article/c0a918b5772f42eca15b2c1829617bd7 |
| PMID | 32764422 |
| PQID | 2431814736 |
| PQPubID | 23479 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_c0a918b5772f42eca15b2c1829617bd7 pubmedcentral_primary_oai_pubmedcentral_nih_gov_7466317 proquest_miscellaneous_2431814736 pubmed_primary_32764422 crossref_primary_10_3390_medicina56080392 crossref_citationtrail_10_3390_medicina56080392 |
| PublicationCentury | 2000 |
| PublicationDate | 20200805 |
| PublicationDateYYYYMMDD | 2020-08-05 |
| PublicationDate_xml | – month: 8 year: 2020 text: 20200805 day: 5 |
| PublicationDecade | 2020 |
| PublicationPlace | Switzerland |
| PublicationPlace_xml | – name: Switzerland |
| PublicationTitle | Medicina (Kaunas, Lithuania) |
| PublicationTitleAlternate | Medicina (Kaunas) |
| PublicationYear | 2020 |
| Publisher | MDPI MDPI AG |
| Publisher_xml | – name: MDPI – name: MDPI AG |
| References | Tubach (ref_31) 2009; 60 Solovic (ref_22) 2010; 36 Ai (ref_29) 2015; 42 ref_13 Arkema (ref_6) 2015; 74 ref_34 ref_11 ref_10 Settas (ref_26) 2007; 13 Chan (ref_32) 2018; 43 Zhang (ref_20) 2017; 7 Andonopoulos (ref_17) 1998; 17 Wolfe (ref_8) 2004; 50 Keane (ref_21) 2001; 345 Askling (ref_7) 2005; 52 Marie (ref_1) 2005; 53 Bouza (ref_3) 2001; 15 Brassard (ref_18) 2009; 61 Yamada (ref_5) 2006; 65 Mertens (ref_25) 2009; 36 Baronnet (ref_33) 2011; 78 Dheda (ref_24) 2016; 387 Gaitonde (ref_14) 2002; 61 Minozzi (ref_2) 2016; 15 Carmona (ref_19) 2003; 48 Aydin (ref_23) 2019; 44 Tocque (ref_30) 1998; 158 Seong (ref_12) 2007; 34 Carmona (ref_4) 2003; 30 Agrawal (ref_15) 2000; 48 ref_28 Falagas (ref_16) 2007; 30 ref_9 Ramiro (ref_27) 2017; 76 |
| References_xml | – ident: ref_9 – volume: 17 start-page: 181 year: 1998 ident: ref_17 article-title: Is a purified protein derivative skin test and subsequent antituberculous chemoprophylaxis really necessary in systemic rheumatic disease patients receiving corticosteroids? publication-title: Clin. Rheumatol. doi: 10.1007/BF01451043 – volume: 15 start-page: 335 year: 2001 ident: ref_3 article-title: Infections in systemic lupus erythematosus and rheumatoid arthritis publication-title: Infect. Dis. Clin. N. Am. doi: 10.1016/S0891-5520(05)70149-5 – volume: 42 start-page: 2229 year: 2015 ident: ref_29 article-title: The Risk of Tuberculosis in Patients with Rheumatoid Arthritis Treated with Tumor Necrosis Factor-α Antagonist: A Metaanalysis of Both Randomized Controlled Trials and Registry/Cohort Studies publication-title: J. Rheumatol. doi: 10.3899/jrheum.150057 – volume: 48 start-page: 881 year: 2000 ident: ref_15 article-title: Incidence of tuberculosis among patients receiving treatment with oral corticosteroids publication-title: J. Assoc. Phys. India – ident: ref_11 – volume: 345 start-page: 1098 year: 2001 ident: ref_21 article-title: Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa011110 – volume: 36 start-page: 1118 year: 2009 ident: ref_25 article-title: Anakinra for rheumatoid arthritis: A systematic review publication-title: J. Rheumatol. doi: 10.3899/jrheum.090074 – volume: 30 start-page: 1436 year: 2003 ident: ref_4 article-title: Increased risk of tuberculosis in patients with rheumatoid arthritis publication-title: J. Rheumatol. – volume: 74 start-page: 1212 year: 2015 ident: ref_6 article-title: Are patients with Rheumatoid arthritis still at an increased risk of tuberculosis and what is the role of biological treatments? publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2013-204960 – volume: 61 start-page: 300 year: 2009 ident: ref_18 article-title: Rheumatoid arthritis, its treatments, and the risk of tuberculosis in Quebec, Canada publication-title: Arthritis Rheum. doi: 10.1002/art.24476 – volume: 30 start-page: 477 year: 2007 ident: ref_16 article-title: Tuberculosis in patients with systemic rheumatic or pulmonary diseases treated with glucocorticosteroids and the preventive role of isoniazid: A review of the available evidence publication-title: Int. J. Antimicrob. Agents doi: 10.1016/j.ijantimicag.2007.07.010 – volume: 65 start-page: 1661 year: 2006 ident: ref_5 article-title: Increased risk of tuberculosis in patients with rheumatoid arthritis in Japan publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2005.047274 – volume: 61 start-page: 251 year: 2002 ident: ref_14 article-title: Efficacy of isoniazid prophylaxis in patients with systemic lupus erythematosus receiving long term steroid treatment publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.61.3.251 – volume: 50 start-page: 372 year: 2004 ident: ref_8 article-title: Tuberculosis infection in patients with rheumatoid arthritis and the effect of infliximab therapy publication-title: Arthritis Rheum. doi: 10.1002/art.20009 – volume: 44 start-page: 553 year: 2019 ident: ref_23 article-title: Relative risk of tuberculosis in patients with rheumatic diseases managed with anti-tumour necrosis factor-alpha therapy: A nationwide cohort study publication-title: J. Clin. Pharm. Ther. doi: 10.1111/jcpt.12814 – volume: 78 start-page: 279 year: 2011 ident: ref_33 article-title: Incidence of tuberculosis in patients with rheumatoid arthritis. A systematic literature review publication-title: Jt. Bone Spine doi: 10.1016/j.jbspin.2010.12.004 – ident: ref_28 doi: 10.1371/journal.pone.0178035 – volume: 34 start-page: 706 year: 2007 ident: ref_12 article-title: Incidence of tuberculosis in Korean patients with rheumatoid arthritis (RA): Effects of RA itself and of tumor necrosis factor blockers publication-title: J. Rheumatol. – volume: 36 start-page: 1185 year: 2010 ident: ref_22 article-title: The risk of tuberculosis related to tumour necrosis factor antagonist therapies: A TBNET consensus statement publication-title: Eur. Respir. J. doi: 10.1183/09031936.00028510 – volume: 48 start-page: 2122 year: 2003 ident: ref_19 article-title: Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active-surveillance report publication-title: Arthritis Rheum. doi: 10.1002/art.11137 – ident: ref_10 – ident: ref_13 doi: 10.1093/rap/rkz020 – volume: 158 start-page: 484 year: 1998 ident: ref_30 article-title: Long-term trends in tuberculosis. Comparison of age-cohort data between Hong Kong and England and Wales publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.158.2.9709125 – volume: 15 start-page: 11 year: 2016 ident: ref_2 article-title: Risk of infections using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: A systematic review and meta-analysis publication-title: Expert Opin. Drug Saf. doi: 10.1080/14740338.2016.1240783 – volume: 53 start-page: 155 year: 2005 ident: ref_1 article-title: Opportunistic infections in polymyositis and dermatomyositis publication-title: Arthritis Rheum. doi: 10.1002/art.21083 – volume: 60 start-page: 1884 year: 2009 ident: ref_31 article-title: Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective French Research Axed on Tolerance of Biotherapies registry publication-title: Arthritis Rheum. doi: 10.1002/art.24632 – volume: 13 start-page: 219 year: 2007 ident: ref_26 article-title: Reactivation of pulmonary tuberculosis in a patient with rheumatoid arthritis during treatment with IL-1 receptor antagonists (anakinra) publication-title: J. Clin. Rheumatol. Pract. Rep. Rheum. Musculoskelet. Dis. – volume: 52 start-page: 1986 year: 2005 ident: ref_7 article-title: Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden publication-title: Arthritis Rheum. doi: 10.1002/art.21137 – volume: 76 start-page: 1101 year: 2017 ident: ref_27 article-title: Safety of synthetic and biological DMARDs: A systematic literature review informing the 2016 update of the EULAR recommendations for management of rheumatoid arthritis publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2016-210708 – volume: 43 start-page: 256 year: 2018 ident: ref_32 article-title: Risk of tuberculosis comparison in new users of antitumour necrosis factor-α and with existing disease-modifying antirheumatic drug therapy publication-title: J. Clin. Pharm. Ther. doi: 10.1111/jcpt.12644 – volume: 387 start-page: 1211 year: 2016 ident: ref_24 article-title: Tuberculosis publication-title: Lancet Lond. Engl. doi: 10.1016/S0140-6736(15)00151-8 – volume: 7 start-page: e012567 year: 2017 ident: ref_20 article-title: Risk of tuberculosis in patients treated with TNF-α antagonists: A systematic review and meta-analysis of randomised controlled trials publication-title: BMJ Open doi: 10.1136/bmjopen-2016-012567 – ident: ref_34 doi: 10.3390/medicina47030026 |
| SSID | ssj0032572 |
| Score | 2.209143 |
| Snippet | Background and objective: With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more... With an increase in survival rates among rheumatic patients, comorbidities and infections, in particular, have gained more importance, especially after the... |
| SourceID | doaj pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 392 |
| SubjectTerms | Adolescent Adult Aged Cohort Studies Female Humans Incidence Lithuania - epidemiology Male Middle Aged Retrospective Studies rheumatic diseases Rheumatic Fever - diagnosis Rheumatic Fever - epidemiology Risk Factors tuberculosis Tuberculosis - diagnosis Tuberculosis - epidemiology |
| Title | Incidence of Tuberculosis in Inflammatory Rheumatic Diseases: Results from a Lithuanian Retrospective Cohort Study |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/32764422 https://www.proquest.com/docview/2431814736 https://pubmed.ncbi.nlm.nih.gov/PMC7466317 https://doaj.org/article/c0a918b5772f42eca15b2c1829617bd7 |
| Volume | 56 |
| WOSCitedRecordID | wos000564049300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Open Access Full Text customDbUrl: eissn: 1648-9144 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0032572 issn: 1648-9144 databaseCode: DOA dateStart: 20070101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1648-9144 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0032572 issn: 1648-9144 databaseCode: 7X7 dateStart: 20180101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1648-9144 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0032572 issn: 1648-9144 databaseCode: BENPR dateStart: 20180101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1648-9144 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0032572 issn: 1648-9144 databaseCode: PIMPY dateStart: 20180101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3di9QwEA96ityL-O36sUTwxYeybZo0qW_eeYcH3rIsJ6xPZZIm7MLaSj8O_O-dNN3l9hB98aXQpqVDZpL5Db_JDCHvWabi1ACPDOLbiKvcRKA1RM6HG2UKaQxuaDYh53O1WuWLG62-fE5YKA8cJm5mYsgTpQWiQMeZNZAIzQyi4hx9ry6Hc-SIenbBVNiDUzTEwHPiLpNl8SoQlCkG-LORswZ09Shmzg4c0lC3_09g83bO5A0ndP6IPBzRI_0UpH5M7tjqCXlwOfLjT0mDyz10CaW1o1e9to3pt3W7aemmoheVQ_3_GHh1ulzbfijXSj8Hjqb9SJe27bddS_2ZEwr066Zb91ChAeFI19S7U5n0tF4jaqc-B_HXM_Lt_Ozq9Es0dlWIDM9YFynDrRK43wJIDQkDATYV1kmQMSud4IlNLAjhtE107FgJsdUlAjOncmEcpM_JUVVX9iWhJWKvMmel0YZzjDtUVmYqs4mMlTVZLiZktpvawowlx33ni22BoYdXRnFbGRPyYf_Fz1Bu4y_vnnht7d_zhbKHB2g-xWg-xb_MZ0Le7XRd4MLybAlUtu7bgiG0UgmXaTYhL4Lu979KmUQcyVAEeWAVB7IcjlSb9VC8W3LEeIl89T-Ef02OmQ__fQaLeEOOuqa3b8l9c91t2mZK7sqVHK5qSu6dnM0Xy-mwSvBucXG5-P4bOyAZBA |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Incidence+of+Tuberculosis+in+Inflammatory+Rheumatic+Diseases%3A+Results+from+a+Lithuanian+Retrospective+Cohort+Study&rft.jtitle=Medicina+%28Kaunas%2C+Lithuania%29&rft.au=Miltinien%C4%97%2C+Dalia&rft.au=Deresevi%C4%8Dien%C4%97%2C+Giedr%C4%97&rft.au=Nak%C4%8Derien%C4%97%2C+Birut%C4%97&rft.au=Davidavi%C4%8Dien%C4%97%2C+Valerija+Edita&rft.date=2020-08-05&rft.issn=1648-9144&rft.eissn=1648-9144&rft.volume=56&rft.issue=8&rft.spage=392&rft_id=info:doi/10.3390%2Fmedicina56080392&rft.externalDBID=n%2Fa&rft.externalDocID=10_3390_medicina56080392 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1648-9144&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1648-9144&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1648-9144&client=summon |