Targeting VEGF/VEGFR to Modulate Antitumor Immunity

In addition to the crucial role in promoting the growth of tumor vessels, vascular endothelial growth factor (VEGF) is also immunosuppressive. VEGF can inhibit the function of T cells, increase the recruitment of regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs), and hinder the...

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Vydané v:	Frontiers in immunology Ročník 9; s. 978
Hlavní autori:	Yang, Ju, Yan, Jing, Liu, Baorui
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers Media S.A 03.05.2018
Predmet:	angiogenesis Angiogenesis Inhibitors - pharmacology Animals Cell Differentiation - immunology Dendritic Cells - immunology Humans immune Immunologic Factors - pharmacology Immunology Mice Myeloid-Derived Suppressor Cells - immunology Neoplasms - immunology Neovascularization, Pathologic Receptors, Vascular Endothelial Growth Factor - immunology T cells T-Lymphocytes, Regulatory - immunology tumor vascular endothelial growth factor Vascular Endothelial Growth Factors - immunology immune T cells angiogenesis tumor vascular endothelial growth factor
ISSN:	1664-3224, 1664-3224
On-line prístup:	Získať plný text
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