Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines

Abstract Coronavirus disease 2019 (COVID-19) has caused a global pandemic in just a few months, causing millions infected. Nearly 20% of COVID-19 patients present severe coagulation abnormalities, which may occur in almost all of the severe and critical ill COVID-19 cases. Concomitant venous thrombo...

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Vydáno v:Thrombosis and haemostasis Ročník 120; číslo 6; s. 937 - 948
Hlavní autoři: Zhai, Zhenguo, Li, Chenghong, Chen, Yaolong, Gerotziafas, Grigorios, Zhang, Zhenlu, Wan, Jun, Liu, Peng, Elalamy, Ismaïl, Wang, Chen
Médium: Journal Article
Jazyk:angličtina
Vydáno: Stuttgart · New York Georg Thieme Verlag KG 01.06.2020
Témata:
Anticoagulants - therapeutic use
Betacoronavirus
Blood Coagulation Disorders - drug therapy
China - epidemiology
Consensus
Coronavirus Infections - blood
Coronavirus Infections - complications
Coronavirus Infections - therapy
COVID-19
Critical Illness
Europe - epidemiology
Fibrin Fibrinogen Degradation Products - analysis
Hemorrhage - prevention & control
Humans
Pandemics
Pneumonia, Viral - blood
Pneumonia, Viral - complications
Pneumonia, Viral - therapy
Pulmonary Embolism - complications
Pulmonary Embolism - prevention & control
Registries
Review Article
Risk Assessment
Risk Factors
SARS-CoV-2
Treatment Outcome
Venous Thromboembolism - complications
Venous Thromboembolism - prevention & control
Venous Thromboembolism - therapy
Venous Thrombosis - complications
Venous Thrombosis - prevention & control
China
Europe
COVID-19
consensus
coagulation abnormalities
prophylaxis
venous thromboembolism
ISSN:0340-6245, 2567-689X, 2567-689X
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Shrnutí:Abstract Coronavirus disease 2019 (COVID-19) has caused a global pandemic in just a few months, causing millions infected. Nearly 20% of COVID-19 patients present severe coagulation abnormalities, which may occur in almost all of the severe and critical ill COVID-19 cases. Concomitant venous thromboembolism (VTE), a potential cause of unexplained deaths, has been frequently reported in COVID-19 cases, but its management is still challenging due to the complexity between antithrombotic therapy and coagulation disorders. Based on frontline practical experience and comprehensive literature review, here a panel of experts and physicians from China and Europe developed an evidence and opinion-based consensus on the prophylaxis and management of VTE associated with COVID-19. This statement aims for clinicians treating COVID-19 and provides practical recommendations in detailed situations, for example, how to choose thromboprophylactic measures for patients with diverse severity of disease and bleeding risk, or which kind of anticoagulant should be prescribed. With limited experience on COVID19-associated VTE, this expert consensus statement should be helpful for clinicians worldwide with specific suggestions.
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ISSN:0340-6245
2567-689X
2567-689X
DOI:10.1055/s-0040-1710019