Cadmium Levels in Tissue and Plasma as a Risk Factor for Prostate Carcinoma: a Meta-Analysis

Cadmium is a heavy metal that has been suggested to be a carcinogen by evidence. A number of published studies have investigated the association between cadmium levels and prostate cancer, but the results were inconsistent. Thus, we conducted a meta-analysis to get a precise estimate of this subject...

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Veröffentlicht in:Biological trace element research Jg. 172; H. 1; S. 86 - 92
Hauptverfasser: Zhang, Liang, Yi Zhu, Rui Hao, Mengmeng Shao, Yunbo Luo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New York Springer US 01.07.2016
Springer Nature B.V
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Biotechnology
Cadmium
Cadmium - analysis
Cadmium - blood
carcinogenesis
carcinogens
confidence interval
Heavy metals
Humans
Life Sciences
Male
Meta-analysis
Nutrition
Oncology
patients
Plasma
Prostate cancer
prostatic neoplasms
Prostatic Neoplasms - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - metabolism
Risk assessment
Risk Factors
screening
tissues
Cadmium
Prostate carcinoma
Levels
Risk
Meta-analysis
ISSN:0163-4984, 1559-0720
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:Cadmium is a heavy metal that has been suggested to be a carcinogen by evidence. A number of published studies have investigated the association between cadmium levels and prostate cancer, but the results were inconsistent. Thus, we conducted a meta-analysis to get a precise estimate of this subject. After a careful searching and screening, a total of 11 publications containing 14 separated studies were included. Based on a random-effect model, the pooled data showed that cadmium levels of prostate tissues (standard mean difference (SMD) = 3.17, 95 % confidence interval (CI) = 0.60–5.74, P 
Bibliographie:http://dx.doi.org/10.1007/s12011-015-0576-0
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ISSN:0163-4984
1559-0720
DOI:10.1007/s12011-015-0576-0