Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein

Cockayne syndrome (CS) is a nucleotide excision repair disorder characterized by sun (UV) sensitivity and severe developmental problems. Two genes have been shown to be involved: CSA and CSB. Both proteins play an essential role in preferential repair of transcription-blocking lesions from active ge...

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Vydané v:	The Journal of biological chemistry Ročník 273; číslo 19; s. 11844
Hlavní autori:	Citterio, E, Rademakers, S, van der Horst, G T, van Gool, A J, Hoeijmakers, J H, Vermeulen, W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 08.05.1998
Predmet:	Adenosine Triphosphatases - metabolism Cells, Cultured Cockayne Syndrome - genetics DNA Helicases - chemistry DNA Helicases - genetics DNA Helicases - isolation & purification DNA Helicases - metabolism DNA Repair DNA Repair Enzymes Humans Kinetics Poly-ADP-Ribose Binding Proteins Recombinant Proteins RNA - biosynthesis Structure-Activity Relationship
ISSN:	0021-9258
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