Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis

Mycobacterium bovis is an intracellular pathogen that causes tuberculosis in cattle. Following infection, the pathogen resides and persists inside host macrophages by subverting host immune responses via a diverse range of mechanisms. Here, a high-density bovine microarray platform was used to exami...

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Veröffentlicht in:	Frontiers in immunology Jg. 5; S. 422
Hauptverfasser:	Killick, Kate E., Magee, David A., Park, Stephen D. E., Taraktsoglou, Maria, Browne, John A., Conlon, Kevin M., Nalpas, Nicolas C., Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E., Hokamp, Karsten
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 01.10.2014
Schlagworte:	BCG Cattle Immunology macrophage Mycobacterium bovis network Tuberculosis Mycobacterium bovis BCG tuberculosis macrophage cattle gene interaction network network
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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