Updates on obesity and the obesity paradox in cardiovascular diseases

The prevalence of obesity has reached pandemic proportions worldwide and certainly in the United States. Obesity is a well-established independent risk factor for development of many cardiovascular diseases (CVD), including heart failure, coronary heart disease, atrial fibrillation, and hypertension...

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Bibliographic Details
Published in:Progress in cardiovascular diseases Vol. 78; pp. 2 - 10
Main Authors: Tutor, Austin W., Lavie, Carl J., Kachur, Sergey, Milani, Richard V., Ventura, Hector O.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01.05.2023
Subjects:
Cardiac fitness
Cardiorespiratory fitness
Cardiovascular
Fitness outcomes
Obesity paradox
CRET
HTN
AF
HFpEF
WC
HFrEF
CR
CVD
PA
Cardiac fitness
CRF
Obesity paradox
Cardiorespiratory fitness
Fitness outcomes
MET
CHD
HF
BMI
Physical activity
Heart failure preserved ejection fraction
Heart failure reduced ejection fraction
Cardiovascular disease
Body mass index
Cardiac rehab exercise therapy
Heart failure
Hypertension
Atrial fibrillation
Coronary heart disease
Metabolic equivalent
Cardiac rehab
Waist Circumference
ISSN:0033-0620, 1873-1740, 1532-8643, 1873-1740
Online Access:Get full text
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Summary:The prevalence of obesity has reached pandemic proportions worldwide and certainly in the United States. Obesity is a well-established independent risk factor for development of many cardiovascular diseases (CVD), including heart failure, coronary heart disease, atrial fibrillation, and hypertension. Therefore, it is logical to expect obesity would have a strong correlation with CVD mortality. However, a substantial body of literature demonstrates a paradox with improved prognosis of overweight and obese patients with established CVD compared to lean patients with the identical CVD. Surprisingly, similar data has also shown that cardiovascular fitness, rather than weight loss alone, influences the relationship between obesity and mortality in those with established CVD. The impact of fitness, exercise, physical activity (PA), and weight loss and their relationship to the obesity paradox are all reviewed here.
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ISSN:0033-0620
1873-1740
1532-8643
1873-1740
DOI:10.1016/j.pcad.2022.11.013