Genetic and Functional Associations with Decreased Anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in Macrophages from Subjects with Axial Spondyloarthritis

Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is an anti-inflammatory protein implicated in multiple autoimmune and rheumatologic conditions. We hypothesized that lower levels of TNFAIP3 contributes to excessive cytokine production in response to inflammatory stimuli in axial spondyloarthr...

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Vydáno v:	Frontiers in immunology Ročník 8; s. 860
Hlavní autoři:	Liu, Yiping, Ye, Zhan, Li, Xiang, Anderson, Jennifer L., Khan, Mike, DaSilva, Douglas, Baron, Marissa, Wilson, Deborah, Bocoun, Vera, Ivacic, Lynn C., Schrodi, Steven J., Smith, Judith A.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland Frontiers Media S.A 24.07.2017
Témata:	cytokine production genetic variants Immunology macrophages spondyloarthritis spondyloarthritis pathogenesis tumor necrosis factor alpha-induced protein 3 genetic variants cytokine production spondyloarthritis spondyloarthritis pathogenesis macrophages TNF-α tumor necrosis factor alpha-induced protein 3
ISSN:	1664-3224, 1664-3224
On-line přístup:	Získat plný text
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