Genetic and Functional Associations with Decreased Anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in Macrophages from Subjects with Axial Spondyloarthritis

Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is an anti-inflammatory protein implicated in multiple autoimmune and rheumatologic conditions. We hypothesized that lower levels of TNFAIP3 contributes to excessive cytokine production in response to inflammatory stimuli in axial spondyloarthr...

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Veröffentlicht in:	Frontiers in immunology Jg. 8; S. 860
Hauptverfasser:	Liu, Yiping, Ye, Zhan, Li, Xiang, Anderson, Jennifer L., Khan, Mike, DaSilva, Douglas, Baron, Marissa, Wilson, Deborah, Bocoun, Vera, Ivacic, Lynn C., Schrodi, Steven J., Smith, Judith A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 24.07.2017
Schlagworte:	cytokine production genetic variants Immunology macrophages spondyloarthritis spondyloarthritis pathogenesis tumor necrosis factor alpha-induced protein 3 genetic variants cytokine production spondyloarthritis spondyloarthritis pathogenesis macrophages TNF-α tumor necrosis factor alpha-induced protein 3
ISSN:	1664-3224, 1664-3224
Online-Zugang:	Volltext
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