GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

Iron-dependent lipid peroxidation is a complex oxidative process where phospholipid hydroperoxides (PLOOH) are produced in membranes and finally transformed into a series of decomposition products, some of which are endowed with biological activity. It is specifically prevented by glutathione peroxi...

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Bibliographic Details

Published in:	Antioxidants & redox signaling Vol. 29; no. 1; p. 61
Main Authors:	Maiorino, Matilde, Conrad, Marcus, Ursini, Fulvio
Format:	Journal Article
Language:	English
Published:	United States 01.07.2018
Subjects:	alpha-Tocopherol - pharmacology Animals Cell Death - drug effects Glutathione Peroxidase - antagonists & inhibitors Glutathione Peroxidase - metabolism Humans Iron Chelating Agents - pharmacology Lipid Peroxidation - drug effects tocopherol ferroptosis peroxidation inhibiting protein glutathione PHGPx
ISSN:	1557-7716, 1557-7716
Online Access:	Get more information
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