Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities

Huge quantities of byproducts/wastes generated in onion processing are usually discarded, but they are excellent sources of bioactive compounds and phytochemicals. However, with growing interest in the sustainable use of resources and the circular economy to reduce adverse impacts on the environment...

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Published in:Biomedicine & pharmacotherapy Vol. 146; p. 112498
Main Authors: Kumar, Manoj, Barbhai, Mrunal D., Hasan, Muzaffar, Punia, Sneh, Dhumal, Sangram, Radha, Rais, Nadeem, Chandran, Deepak, Pandiselvam, R., Kothakota, Anjineyulu, Tomar, Maharishi, Satankar, Varsha, Senapathy, Marisennayya, Anitha, T., Dey, Abhijit, Sayed, Ali A.S., Gadallah, Farouk M., Amarowicz, Ryszard, Mekhemar, Mohamed
Format: Journal Article
Language:English
Published: France Elsevier Masson SAS 01.02.2022
Subjects:
Anti-Infective Agents - pharmacology
Anti-Obesity Agents - pharmacology
Antineoplastic Agents - pharmacology
Antioxidants - pharmacology
Bioactives
Biofunctionalities
Cardiotonic Agents - pharmacology
Flavonoids - pharmacology
Hypoglycemic Agents - pharmacology
Neuroprotective Agents - pharmacology
Onion peel/skin
Onions - chemistry
Phenols - pharmacology
Phytochemicals
Phytochemicals - pharmacology
Plant Extracts - pharmacology
Phytochemicals
Onion peel/skin
Biofunctionalities
Bioactives
ISSN:0753-3322, 1950-6007, 1950-6007
Online Access:Get full text
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Summary:Huge quantities of byproducts/wastes generated in onion processing are usually discarded, but they are excellent sources of bioactive compounds and phytochemicals. However, with growing interest in the sustainable use of resources and the circular economy to reduce adverse impacts on the environment, food processing wastes such as onion peel/skin can be extracted and employed as inputs in developing or reformulating nutrient supplements, and pharmacological drugs. This review highlights major bioactive components, especially total phenolics, total flavonoid, quercetin and its derivatives present in onion peel/skin and their therapeutic applications as cardioprotective, neuroprotective, antiobesity, antidiabetic, anticancer and antimicrobial agents. The present review emphasized that onion peel is one of the important agricultural by-products which is rich in bioactive compounds and can be utilized as health promoting ingredient especially in pharmacological and biomedical fields. Thus, with increasing burden of life style disorders/non-communicable diseases, finding suitable natural alternative for their treatment is one major concern of the researchers and onion peel and its extract can be exploited as a prime ingredient. •Exhaustive review considering extraction of onion peel bioactives and its characterization.•Bifunctionalities associated with onion peel extracts are discussed.•Bioactives exhibit antioxidant, antidiabetic, neuroprotective, and cardioprotective effects.•Onion peel have multifaceted application in fields of biomedicine and pharmaceuticals.
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ISSN:0753-3322
1950-6007
1950-6007
DOI:10.1016/j.biopha.2021.112498