Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon

Chronic inflammatory illnesses are debilitating and recurrent conditions associated with significant comorbidities, including an increased risk of developing cancer. Extensive tissue remodeling is a hallmark of such illnesses, and is both a consequence and a mediator of disease progression. Despite...

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Veröffentlicht in:	Cellular and molecular gastroenterology and hepatology Jg. 17; H. 4; S. 639 - 656
Hauptverfasser:	Moutin, Elisa B., Bons, Joanna, Giavara, Giada, Lourenco, Filipe, Pan, Deng, Burton, Jordan B., Shah, Samah, Colombé, Mathilde, Gascard, Philippe, Tlsty, Thea, Schilling, Birgit, Winton, Douglas J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 2024
Schlagworte:	Animals Cell-Matrix Interactions Chronic Disease Colitis - pathology DIA Proteomics Disease Progression Extracellular Matrix - metabolism Gastroenterology and Hepatology Inflammatory Bowel Disease Mice Proteoglycans Proteomics DIA Proteomics Proteoglycans Grem1 SDS DTT MS iRT It ACN ECM UC Serpin H1 SLRP TEAB Cell-Matrix Interactions TGF-β Lamc1 Inflammatory Bowel Disease FA DIA triethylammonium bicarbonate Integrin mass spectrometry sodium dodecyl sulfate acetonitrile ulcerative colitis formic acid dithiothreitol Laminin subunit gamma 1 data-independent acquisition indexed retention time transforming growth factor-β Gremlin 1 small leucine-rich proteoglycan extracellular matrix Serpin family H member 1
ISSN:	2352-345X, 2352-345X
Online-Zugang:	Volltext
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