Life of RISC: Formation, action, and degradation of RNA-induced silencing complex

Small RNAs regulate a wide variety of biological processes by repressing the expression of target genes at the transcriptional and post-transcriptional levels. To achieve these functions, small RNAs form RNA-induced silencing complex (RISC) together with a member of the Argonaute (AGO) protein famil...

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Bibliographic Details
Published in:	Molecular cell Vol. 82; no. 1; p. 30
Main Authors:	Iwakawa, Hiro-Oki, Tomari, Yukihide
Format:	Journal Article
Language:	English
Published:	United States 06.01.2022
Subjects:	Animals Argonaute Proteins - genetics Argonaute Proteins - metabolism Humans MicroRNAs - genetics MicroRNAs - metabolism Protein Binding Protein Stability Proteolysis RNA - genetics RNA - metabolism RNA Stability RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Small Interfering - genetics RNA, Small Interfering - metabolism RNA-Induced Silencing Complex - genetics RNA-Induced Silencing Complex - metabolism
ISSN:	1097-4164, 1097-4164
Online Access:	Get more information
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