Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma

Summary High plasma levels of nicotinamide phosphoribosyltransferase (NAMPT), traditionally considered an intracellular enzyme with a key role in NAD synthesis, have been reported in several oncological, inflammatory and metabolic diseases. We now show that eNAMPT can be actively released by melanom...

Full description

Saved in:

Bibliographic Details
Published in:	Pigment cell and melanoma research Vol. 28; no. 6; pp. 718 - 729
Main Authors:	Grolla, Ambra A., Torretta, Simone, Gnemmi, Ilaria, Amoruso, Angela, Orsomando, Giuseppe, Gatti, Marco, Caldarelli, Antonio, Lim, Dmitry, Penengo, Lorenza, Brunelleschi, Sandra, Genazzani, Armando A., Travelli, Cristina
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01.11.2015 Wiley Subscription Services, Inc
Subjects:	Animals Autocrine Communication - drug effects Cell Hypoxia - drug effects Cell Line, Tumor cytokine Cytokines - blood Cytokines - metabolism Extracellular Space - enzymology Humans Hydrogen Peroxide - pharmacology Melanoma Melanoma - enzymology Melanoma - pathology Metabolic disorders Mice, Inbred C57BL Monocytes - drug effects Monocytes - metabolism NAD Nicotinamide phosphoribosyltransferase Nicotinamide Phosphoribosyltransferase - blood Nicotinamide Phosphoribosyltransferase - metabolism Paracrine Communication - drug effects Secretory Vesicles - metabolism Skin Neoplasms - enzymology Skin Neoplasms - pathology Tumors visfatin NAD cytokine melanoma Nicotinamide phosphoribosyltransferase visfatin
ISSN:	1755-1471, 1755-148X
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!