Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study
The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study). We evaluated Framingham Offspring participants at examinations 2 and 6 (n...
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| Vydáno v: | Journal of the American Heart Association Ročník 12; číslo 23; s. e030764 |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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England
John Wiley and Sons Inc
05.12.2023
Wiley |
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| ISSN: | 2047-9980, 2047-9980 |
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| Abstract | The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study).
We evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age-sex-adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiovascular health status, depending on which method (LE8 versus Life's Simple 7) was used (60% of participants in ideal Life's Simple 7 status were in intermediate LE8 category). On follow-up after examination 2 (median, 30 and 33 years for CVD and death, respectively), we observed 966 CVD events, and 1195 participants died. Participants having LE8≥68 (sample median) were at lower CVD and death risk compared with those with LE8<68 (examination 2: CVD hazard ratio [HR], 0.47 [95% CI, 0.41-0.54]; death HR, 0.55 [95% CI, 0.49-0.62]; all
<0.001). Participants maintaining low LE8 scores during life course were at highest CVD and death risk (CVD: HRs ranging from 1.8 to 2.3;
<0.001; death HR, 1.45 [95% CI, 1.13-1.85];
=0.003 versus high-high group).
Further studies are warranted to elucidate whether the LE8 score is a better marker of CVD and death risk, compared with Life's Simple 7 score. |
|---|---|
| AbstractList | Background The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study). Methods and Results We evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age‐sex–adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiovascular health status, depending on which method (LE8 versus Life's Simple 7) was used (60% of participants in ideal Life's Simple 7 status were in intermediate LE8 category). On follow‐up after examination 2 (median, 30 and 33 years for CVD and death, respectively), we observed 966 CVD events, and 1195 participants died. Participants having LE8≥68 (sample median) were at lower CVD and death risk compared with those with LE8<68 (examination 2: CVD hazard ratio [HR], 0.47 [95% CI, 0.41–0.54]; death HR, 0.55 [95% CI, 0.49–0.62]; all P<0.001). Participants maintaining low LE8 scores during life course were at highest CVD and death risk (CVD: HRs ranging from 1.8 to 2.3; P<0.001; death HR, 1.45 [95% CI, 1.13–1.85]; P=0.003 versus high‐high group). Conclusions Further studies are warranted to elucidate whether the LE8 score is a better marker of CVD and death risk, compared with Life's Simple 7 score. The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study). We evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age-sex-adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiovascular health status, depending on which method (LE8 versus Life's Simple 7) was used (60% of participants in ideal Life's Simple 7 status were in intermediate LE8 category). On follow-up after examination 2 (median, 30 and 33 years for CVD and death, respectively), we observed 966 CVD events, and 1195 participants died. Participants having LE8≥68 (sample median) were at lower CVD and death risk compared with those with LE8<68 (examination 2: CVD hazard ratio [HR], 0.47 [95% CI, 0.41-0.54]; death HR, 0.55 [95% CI, 0.49-0.62]; all <0.001). Participants maintaining low LE8 scores during life course were at highest CVD and death risk (CVD: HRs ranging from 1.8 to 2.3; <0.001; death HR, 1.45 [95% CI, 1.13-1.85]; =0.003 versus high-high group). Further studies are warranted to elucidate whether the LE8 score is a better marker of CVD and death risk, compared with Life's Simple 7 score. The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study).BACKGROUNDThe association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study).We evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age-sex-adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiovascular health status, depending on which method (LE8 versus Life's Simple 7) was used (60% of participants in ideal Life's Simple 7 status were in intermediate LE8 category). On follow-up after examination 2 (median, 30 and 33 years for CVD and death, respectively), we observed 966 CVD events, and 1195 participants died. Participants having LE8≥68 (sample median) were at lower CVD and death risk compared with those with LE8<68 (examination 2: CVD hazard ratio [HR], 0.47 [95% CI, 0.41-0.54]; death HR, 0.55 [95% CI, 0.49-0.62]; all P<0.001). Participants maintaining low LE8 scores during life course were at highest CVD and death risk (CVD: HRs ranging from 1.8 to 2.3; P<0.001; death HR, 1.45 [95% CI, 1.13-1.85]; P=0.003 versus high-high group).METHODS AND RESULTSWe evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age-sex-adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiovascular health status, depending on which method (LE8 versus Life's Simple 7) was used (60% of participants in ideal Life's Simple 7 status were in intermediate LE8 category). On follow-up after examination 2 (median, 30 and 33 years for CVD and death, respectively), we observed 966 CVD events, and 1195 participants died. Participants having LE8≥68 (sample median) were at lower CVD and death risk compared with those with LE8<68 (examination 2: CVD hazard ratio [HR], 0.47 [95% CI, 0.41-0.54]; death HR, 0.55 [95% CI, 0.49-0.62]; all P<0.001). Participants maintaining low LE8 scores during life course were at highest CVD and death risk (CVD: HRs ranging from 1.8 to 2.3; P<0.001; death HR, 1.45 [95% CI, 1.13-1.85]; P=0.003 versus high-high group).Further studies are warranted to elucidate whether the LE8 score is a better marker of CVD and death risk, compared with Life's Simple 7 score.CONCLUSIONSFurther studies are warranted to elucidate whether the LE8 score is a better marker of CVD and death risk, compared with Life's Simple 7 score. |
| Author | Vasan, Ramachandran S. Rempakos, Athanasios Prescott, Brenton Xanthakis, Vanessa Mitchell, Gary F. |
| AuthorAffiliation | 1 Minneapolis Heart Institute Foundation Minneapolis MN 2 Section of Preventive Medicine and Epidemiology, Department of Medicine Boston University School of Medicine Boston MA 5 Department of Epidemiology Boston University School of Public Health Boston MA 3 Cardiovascular Engineering, Inc Norwood MA 4 Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study Framingham MA 7 Department of Biostatistics Boston University School of Public Health Boston MA 6 University of Texas School of Public Health San Antonio TX |
| AuthorAffiliation_xml | – name: 3 Cardiovascular Engineering, Inc Norwood MA – name: 7 Department of Biostatistics Boston University School of Public Health Boston MA – name: 6 University of Texas School of Public Health San Antonio TX – name: 5 Department of Epidemiology Boston University School of Public Health Boston MA – name: 4 Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study Framingham MA – name: 1 Minneapolis Heart Institute Foundation Minneapolis MN – name: 2 Section of Preventive Medicine and Epidemiology, Department of Medicine Boston University School of Medicine Boston MA |
| Author_xml | – sequence: 1 givenname: Athanasios orcidid: 0000-0002-2683-5255 surname: Rempakos fullname: Rempakos, Athanasios organization: Minneapolis Heart Institute Foundation Minneapolis MN – sequence: 2 givenname: Brenton orcidid: 0000-0002-3805-9070 surname: Prescott fullname: Prescott, Brenton organization: Section of Preventive Medicine and Epidemiology, Department of Medicine Boston University School of Medicine Boston MA – sequence: 3 givenname: Gary F. orcidid: 0000-0001-5643-3145 surname: Mitchell fullname: Mitchell, Gary F. organization: Cardiovascular Engineering, Inc Norwood MA – sequence: 4 givenname: Ramachandran S. orcidid: 0000-0001-7357-5970 surname: Vasan fullname: Vasan, Ramachandran S. organization: Section of Preventive Medicine and Epidemiology, Department of Medicine Boston University School of Medicine Boston MA, Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study Framingham MA, Department of Epidemiology Boston University School of Public Health Boston MA, University of Texas School of Public Health San Antonio TX – sequence: 5 givenname: Vanessa orcidid: 0000-0002-7352-621X surname: Xanthakis fullname: Xanthakis, Vanessa organization: Section of Preventive Medicine and Epidemiology, Department of Medicine Boston University School of Medicine Boston MA, Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study Framingham MA, Department of Biostatistics Boston University School of Public Health Boston MA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38014669$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1161/CIRCULATIONAHA.115.017882 10.1186/s12916-023-02824-8 10.1093/eurjpc/zwad040 10.1161/CIRCULATIONAHA.114.009273 10.1016/j.ajpc.2022.100452 10.1186/s12967-022-03839-0 10.5665/sleep.3508 10.1111/jch.13220 10.1016/j.jhep.2022.10.014 10.1371/journal.pone.0267267 10.1161/JAHA.122.025252 10.1016/j.cpcardiol.2022.101540 10.1016/j.ijcard.2015.03.051 10.1007/s00125-007-0786-x 10.1161/CIR.0000000000001078 10.1161/CIRCULATIONAHA.122.060911 10.1161/CIRCULATIONAHA.109.192703 10.1016/j.ahj.2014.12.017 10.1177/2047487315602015 10.1016/j.sleep.2014.07.018 10.1001/jama.2012.339 10.1161/ATVBAHA.116.307920 10.1007/s40292-022-00555-0 10.1161/CIR.0000000000000444 10.1161/JAHA.118.008741 10.1093/sleep/31.5.645 10.1001/jamacardio.2020.0140 10.1001/jamacardio.2020.0109 10.1161/CIRCULATIONAHA.111.081083 10.1212/WNL.0000000000010306 10.1161/STROKEAHA.113.678839 10.1161/CIRCOUTCOMES.119.006450 10.1161/CIRCHEARTFAILURE.115.002416 10.1111/j.1369-1600.2012.00487.x 10.1161/CIR.0000000000001052 10.1016/j.smrv.2021.101430 10.1038/srep19673 10.1016/j.psyneuen.2022.105843 |
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| Copyright | 2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. |
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| Keywords | American Heart Association cardiovascular disease ideal cardiovascular health Life's Essential 8 |
| Language | English |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This article was sent to Yen‐Hung Lin, MD, PhD, Associate Editor, for review by expert referees, editorial decision, and final disposition. Supplemental Material is available at https://www.ahajournals.org/doi/suppl/10.1161/JAHA.123.030764 For Sources of Funding and Disclosures, see page 10. |
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| References_xml | – ident: e_1_3_1_8_2 doi: 10.1161/CIRCULATIONAHA.115.017882 – ident: e_1_3_1_23_2 doi: 10.1186/s12916-023-02824-8 – volume-title: The Framingham Heart Study, Section 34: An Epidemiological Investigation of Cardiovascular Disease: Some Risk Factors Related to the Annual Incidence of Cardiovascular Disease and Death in Pooled Repeated Biennial Measurements: 30‐Year Follow‐Up year: 1987 ident: e_1_3_1_28_2 – ident: e_1_3_1_24_2 doi: 10.1093/eurjpc/zwad040 – ident: e_1_3_1_13_2 doi: 10.1161/CIRCULATIONAHA.114.009273 – ident: e_1_3_1_18_2 doi: 10.1016/j.ajpc.2022.100452 – ident: e_1_3_1_22_2 doi: 10.1186/s12967-022-03839-0 – ident: e_1_3_1_31_2 doi: 10.5665/sleep.3508 – ident: e_1_3_1_38_2 doi: 10.1111/jch.13220 – ident: e_1_3_1_21_2 doi: 10.1016/j.jhep.2022.10.014 – ident: e_1_3_1_27_2 doi: 10.1371/journal.pone.0267267 – ident: e_1_3_1_39_2 doi: 10.1161/JAHA.122.025252 – ident: e_1_3_1_19_2 doi: 10.1016/j.cpcardiol.2022.101540 – ident: e_1_3_1_15_2 doi: 10.1016/j.ijcard.2015.03.051 – ident: e_1_3_1_37_2 doi: 10.1007/s00125-007-0786-x – ident: e_1_3_1_16_2 doi: 10.1161/CIR.0000000000001078 – ident: e_1_3_1_17_2 doi: 10.1161/CIRCULATIONAHA.122.060911 – ident: e_1_3_1_2_2 doi: 10.1161/CIRCULATIONAHA.109.192703 – ident: e_1_3_1_10_2 doi: 10.1016/j.ahj.2014.12.017 – ident: e_1_3_1_6_2 doi: 10.1177/2047487315602015 – ident: e_1_3_1_35_2 doi: 10.1016/j.sleep.2014.07.018 – ident: e_1_3_1_4_2 doi: 10.1001/jama.2012.339 – ident: e_1_3_1_9_2 doi: 10.1161/ATVBAHA.116.307920 – ident: e_1_3_1_20_2 doi: 10.1007/s40292-022-00555-0 – ident: e_1_3_1_30_2 doi: 10.1161/CIR.0000000000000444 – ident: e_1_3_1_25_2 doi: 10.1161/JAHA.118.008741 – ident: e_1_3_1_36_2 doi: 10.1093/sleep/31.5.645 – ident: e_1_3_1_12_2 doi: 10.1001/jamacardio.2020.0140 – ident: e_1_3_1_3_2 doi: 10.1001/jamacardio.2020.0109 – ident: e_1_3_1_14_2 doi: 10.1161/CIRCULATIONAHA.111.081083 – ident: e_1_3_1_26_2 doi: 10.1212/WNL.0000000000010306 – ident: e_1_3_1_5_2 doi: 10.1161/STROKEAHA.113.678839 – ident: e_1_3_1_11_2 doi: 10.1161/CIRCOUTCOMES.119.006450 – ident: e_1_3_1_7_2 doi: 10.1161/CIRCHEARTFAILURE.115.002416 – ident: e_1_3_1_34_2 doi: 10.1111/j.1369-1600.2012.00487.x – ident: e_1_3_1_40_2 doi: 10.1161/CIR.0000000000001052 – ident: e_1_3_1_32_2 doi: 10.1016/j.smrv.2021.101430 – ident: e_1_3_1_29_2 doi: 10.1038/srep19673 – ident: e_1_3_1_33_2 doi: 10.1016/j.psyneuen.2022.105843 |
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| Snippet | The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and... Background The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease... |
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| SubjectTerms | Adult American Heart Association cardiovascular disease Cardiovascular Diseases - epidemiology Heart Humans ideal cardiovascular health Life's Essential 8 Longitudinal Studies Middle Aged Original Research Risk Factors United States - epidemiology |
| Title | Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study |
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