Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference

Representatives from academia, industry, regulatory agencies, and patient groups convened in March 2019 with the primary goal of developing agreement on chronic HBV treatment endpoints to guide clinical trials aiming to ‘cure’ HBV. Agreement among the conference participants was reached on some key...

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Vydáno v:	Journal of hepatology Ročník 72; číslo 3; s. 539 - 557
Hlavní autoři:	Cornberg, Markus, Lok, Anna Suk-Fong, Terrault, Norah A., Zoulim, Fabien, Berg, Thomas, Brunetto, Maurizia R., Buchholz, Stephanie, Buti, Maria, Chan, Henry L.Y., Chang, Kyong-Mi, Dandri, Maura, Dusheiko, Geoffrey, Feld, Jordan J., Ferrari, Carlo, Ghany, Marc, Janssen, Harry L.A., Kennedy, Patrick, Lampertico, Pietro, Liang, Jake, Locarnini, Stephen, Maini, Mala K., Mishra, Poonam, Papatheodoridis, George, Petersen, Jörg, Schlottmann, Silke, Wang, Su, Wedemeyer, Heiner
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier B.V 01.03.2020 Elsevier Science Ltd
Témata:	Alanine Alanine transaminase Alanine Transaminase - blood Antiviral Agents - therapeutic use Antiviral therapy Bilirubin Biomarkers - blood Clinical trials Clinical Trials, Phase III as Topic - methods Coinfection - blood Coinfection - drug therapy Coinfection - virology CpAM Deoxyribonucleic acid DNA DNA, Viral - blood Hepatitis Hepatitis B Hepatitis B e antigen Hepatitis B surface antigen Hepatitis B Surface Antigens - blood Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B, Chronic - blood Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Hepatitis D Hepatitis D, Chronic - blood Hepatitis D, Chronic - drug therapy Hepatitis D, Chronic - virology Hepatitis Delta Virus - genetics Humans Immunomodulatory therapy Nucleos(t)ide analogues Patients Research Design Ribonucleic acid RNA Sustained Virologic Response CpAM Antiviral therapy Nucleos(t)ide analogues Immunomodulatory therapy Hepatitis B surface antigen Hepatitis D
ISSN:	0168-8278, 1600-0641, 1600-0641
On-line přístup:	Získat plný text
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