Arenavirus Z protein as an antiviral target: virus inactivation and protein oligomerization by zinc finger-reactive compounds

Several disulfide-based and azoic compounds have shown antiviral and virucidal properties against arenaviruses in virus yield-inhibition and inactivation assays, respectively. The most effective virucidal agent, the aromatic disulfide NSC20625, was able to inactivate two strains of the prototype are...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Journal of general virology Ročník 87; číslo Pt 5; s. 1217
Hlavní autoři:	García, Cybele C, Djavani, Mahmoud, Topisirovic, Ivan, Borden, Katherine L B, Salvato, María S, Damonte, Elsa B
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.05.2006
Témata:	Animals Azo Compounds - chemistry Azo Compounds - pharmacology Carrier Proteins - drug effects Cell Line Disulfides - chemistry Disulfides - pharmacology Humans Intracellular Signaling Peptides and Proteins Lymphocytic choriomeningitis virus - drug effects Lymphocytic choriomeningitis virus - physiology Oligodeoxyribonucleotides - metabolism RNA, Viral - biosynthesis RNA, Viral - drug effects Virus Replication - drug effects Zinc Fingers - drug effects
ISSN:	0022-1317
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!