Risk Factors for Polyvascular Involvement in Patients With Peripheral Artery Disease: A Mendelian Randomization Study

Background Atherosclerosis in >1 vascular bed (ie, polyvascular disease), often a feature of peripheral artery disease (PAD), is associated with high morbidity and mortality. We sought to identify risk factors for polyvascular involvement in patients with PAD. Methods and Results We performed 2-s...

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Bibliographic Details
Published in:	Journal of the American Heart Association Vol. 9; no. 24; p. e017740
Main Authors:	Dikilitas, Ozan, Satterfield, Benjamin A., Kullo, Iftikhar J.
Format:	Journal Article
Language:	English
Published:	England John Wiley and Sons Inc 15.12.2020 Wiley
Subjects:	Aged Algorithms Aortic Aneurysm, Abdominal - epidemiology Aortic Aneurysm, Abdominal - genetics atherosclerosis Atherosclerosis - mortality blood pressure Brief Communication Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - genetics Coronary Disease - epidemiology Coronary Disease - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study - methods Glycated Hemoglobin - analysis Humans Hypertension - complications Hypertension - genetics lipoproteins Lipoproteins - adverse effects Lipoproteins - blood Male Mendelian randomization Mendelian Randomization Analysis - methods Middle Aged Odds Ratio Peripheral Arterial Disease - genetics Peripheral Arterial Disease - pathology peripheral artery disease Phenotype polyvascular disease Risk Factors Smoking - epidemiology atherosclerosis blood pressure peripheral artery disease Mendelian randomization polyvascular disease lipoproteins
ISSN:	2047-9980, 2047-9980
Online Access:	Get full text
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