Use of a Flexible Inflatable Multi-Channel Applicator for Vaginal Brachytherapy in the Management of Gynecologic Cancer
Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation. Twenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each re...
Uloženo v:
| Vydáno v: | Frontiers in oncology Ročník 5; s. 201 |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
Switzerland
Frontiers Media S.A
14.09.2015
|
| Témata: | |
| ISSN: | 2234-943X, 2234-943X |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation.
Twenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by three weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5 mm depth to 1500 cGy/3 fractions with a simultaneous integrated boost totaling 2100 cGy/3 fractions to tumor. Modeling of SC and Syed plans was performed using MC scans for each patient. Dosimetry for MC and SC plans was evaluated for PTV700 cGy coverage, maximum dose to 2 cm(3) to bladder, rectum, as well as mucosal surface points. Dosimetry for Syed plans was calculated for PTV700 cGy coverage. Patients were followed for treatment response and toxicity.
Dosimetric analysis between MC and SC plans demonstrated increased tumor coverage (PTV700 cGy), with decreased rectal, bladder, and contralateral vaginal mucosa dose in favor of MC. These differences were significant (p < 0.05). Comparison of MC and Syed plans demonstrated increased tumor coverage in favor of Syed plans which were not significant (p = 0.71). Patients treated with MC had no cancer recurrence or ≥grade 3 toxicity.
Use of MC was efficacious and safe, providing superior coverage of tumor volumes ≤1 cm depth compared to SC and comparable to Syed implant. MC avoids excess dose to surrounding organs compared to SC, and potentially less morbidity than Syed implants. For tumors extending ≤1 cm depth, use of MC represents an alternative to an interstitial implant. |
|---|---|
| AbstractList | Introduction: Evaluate use of novel multi-channel applicator (MC) CapriTM to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation. Material and Methods: 28 plans were evaluated from 4 patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by 3 weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5 mm depth to 1500 cGy/3 fractions with a simultaneous integrated boost totaling 2100 cGy/3 fractions to tumor. Modeling of SC and Syed plans was performed using MC scans for each patient. Dosimetry for MC and SC plans was evaluated for PTV700 cGy coverage, maximum dose to 2cm3 to bladder, rectum as well as mucosal surface points. Dosimetry for Syed plans was calculated for PTV700 cGy coverage. Patients were followed for treatment response and toxicity.Results: Dosimetric analysis between MC and SC plans demonstrated increased tumor coverage (PTV700 cGy), with decreased rectal, bladder, and contralateral vaginal mucosa dose in favor of MC. These differences were significant (p<0.05). Comparison of MC and Syed plans demonstrated increased tumor coverage in favor of Syed plans which were not significant (p=0.71). Patients treated with MC had no cancer recurrence or ≥ grade 3 toxicity.Conclusion: Use of MC was efficacious and safe, providing superior coverage of tumor volumes ≤1cm depth compared to SC and comparable to Syed implant. MC avoids excess dose to surrounding organs compared to SC, and potentially less morbidity than Syed implants. For tumors extending ≤1cm depth, use of MC represents an alternative to an interstitial implant. Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation. Twenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by three weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5 mm depth to 1500 cGy/3 fractions with a simultaneous integrated boost totaling 2100 cGy/3 fractions to tumor. Modeling of SC and Syed plans was performed using MC scans for each patient. Dosimetry for MC and SC plans was evaluated for PTV700 cGy coverage, maximum dose to 2 cm(3) to bladder, rectum, as well as mucosal surface points. Dosimetry for Syed plans was calculated for PTV700 cGy coverage. Patients were followed for treatment response and toxicity. Dosimetric analysis between MC and SC plans demonstrated increased tumor coverage (PTV700 cGy), with decreased rectal, bladder, and contralateral vaginal mucosa dose in favor of MC. These differences were significant (p < 0.05). Comparison of MC and Syed plans demonstrated increased tumor coverage in favor of Syed plans which were not significant (p = 0.71). Patients treated with MC had no cancer recurrence or ≥grade 3 toxicity. Use of MC was efficacious and safe, providing superior coverage of tumor volumes ≤1 cm depth compared to SC and comparable to Syed implant. MC avoids excess dose to surrounding organs compared to SC, and potentially less morbidity than Syed implants. For tumors extending ≤1 cm depth, use of MC represents an alternative to an interstitial implant. Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation.INTRODUCTIONEvaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation.Twenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by three weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5 mm depth to 1500 cGy/3 fractions with a simultaneous integrated boost totaling 2100 cGy/3 fractions to tumor. Modeling of SC and Syed plans was performed using MC scans for each patient. Dosimetry for MC and SC plans was evaluated for PTV700 cGy coverage, maximum dose to 2 cm(3) to bladder, rectum, as well as mucosal surface points. Dosimetry for Syed plans was calculated for PTV700 cGy coverage. Patients were followed for treatment response and toxicity.MATERIALS AND METHODSTwenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by three weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5 mm depth to 1500 cGy/3 fractions with a simultaneous integrated boost totaling 2100 cGy/3 fractions to tumor. Modeling of SC and Syed plans was performed using MC scans for each patient. Dosimetry for MC and SC plans was evaluated for PTV700 cGy coverage, maximum dose to 2 cm(3) to bladder, rectum, as well as mucosal surface points. Dosimetry for Syed plans was calculated for PTV700 cGy coverage. Patients were followed for treatment response and toxicity.Dosimetric analysis between MC and SC plans demonstrated increased tumor coverage (PTV700 cGy), with decreased rectal, bladder, and contralateral vaginal mucosa dose in favor of MC. These differences were significant (p < 0.05). Comparison of MC and Syed plans demonstrated increased tumor coverage in favor of Syed plans which were not significant (p = 0.71). Patients treated with MC had no cancer recurrence or ≥grade 3 toxicity.RESULTSDosimetric analysis between MC and SC plans demonstrated increased tumor coverage (PTV700 cGy), with decreased rectal, bladder, and contralateral vaginal mucosa dose in favor of MC. These differences were significant (p < 0.05). Comparison of MC and Syed plans demonstrated increased tumor coverage in favor of Syed plans which were not significant (p = 0.71). Patients treated with MC had no cancer recurrence or ≥grade 3 toxicity.Use of MC was efficacious and safe, providing superior coverage of tumor volumes ≤1 cm depth compared to SC and comparable to Syed implant. MC avoids excess dose to surrounding organs compared to SC, and potentially less morbidity than Syed implants. For tumors extending ≤1 cm depth, use of MC represents an alternative to an interstitial implant.CONCLUSIONUse of MC was efficacious and safe, providing superior coverage of tumor volumes ≤1 cm depth compared to SC and comparable to Syed implant. MC avoids excess dose to surrounding organs compared to SC, and potentially less morbidity than Syed implants. For tumors extending ≤1 cm depth, use of MC represents an alternative to an interstitial implant. |
| Author | Duckworth, Tamara L. DeWyngaert, J. Keith Cooper, Benjamin T. Lymberis, Stella C. Shin, Samuel M. Curtin, John P. Schiff, Peter B. |
| AuthorAffiliation | 1 Department of Radiation Oncology, NYU Langone Medical Center, NYU Perlmutter Cancer Center , New York, NY , USA 2 Department of Obstetrics and Gynecology, NYU Langone Medical Center , New York, NY , USA |
| AuthorAffiliation_xml | – name: 1 Department of Radiation Oncology, NYU Langone Medical Center, NYU Perlmutter Cancer Center , New York, NY , USA – name: 2 Department of Obstetrics and Gynecology, NYU Langone Medical Center , New York, NY , USA |
| Author_xml | – sequence: 1 givenname: Samuel M. surname: Shin fullname: Shin, Samuel M. – sequence: 2 givenname: Tamara L. surname: Duckworth fullname: Duckworth, Tamara L. – sequence: 3 givenname: Benjamin T. surname: Cooper fullname: Cooper, Benjamin T. – sequence: 4 givenname: John P. surname: Curtin fullname: Curtin, John P. – sequence: 5 givenname: Peter B. surname: Schiff fullname: Schiff, Peter B. – sequence: 6 givenname: J. Keith surname: DeWyngaert fullname: DeWyngaert, J. Keith – sequence: 7 givenname: Stella C. surname: Lymberis fullname: Lymberis, Stella C. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26442213$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kk1v1DAQhi1UREvpmRvykUu2_orjXJDKipaVWnGhiJs1cSZZV157cbLA_nuSbotaJCxZM7LnfWYsv6_JUUwRCXnL2UJKU593KbqFYLxcMDaFF-RECKmKWsnvR0_yY3I2DHdsWrpknMlX5FhopYTg8oT8uh2Qpo4CvQz42zcB6Sp2AUaY05tdGH2xXEOMGOjFdhu8gzFl2k37G_Q-QqAfM7j1flxjhu2e-kinlN5AhB43GMeZfrWP6FJIvXd0CdFhfkNedhAGPHuIp-T28tPX5efi-svVanlxXThV1mNhXOMkk0xzLVtptAEB2AlsyhYYq2TNNJTciEZVuq2QCY7CtK7tBEPBFJenZHXgtgnu7Db7DeS9TeDt_UHKvYU8ehfQsqoUVSOV5NwpMLzuamYEa2stjWIGJ9aHA2u7azbYuulxGcIz6POb6Ne2Tz-tKrWptJ4A7x8AOf3Y4TDajR8chgAR026wvJpmVpUo59J3T3v9bfL4c1NBeShwOQ1Dxs46P8Lo09zaB8uZnU1iZ5PY2ST23iST7vwf3SP6f4o_TvO-sw |
| CitedBy_id | crossref_primary_10_1016_j_meddos_2022_06_001 crossref_primary_10_1016_j_canrad_2021_10_013 crossref_primary_10_1002_mp_15666 |
| Cites_doi | 10.1016/j.radonc.2003.11.006 10.1006/gyno.2000.5727 10.1120/jacmp.v15i1.4581 10.1006/gyno.1999.5487 10.1016/S0167-8140(02)00384-5 10.1016/S0360-3016(97)00576-2 10.1016/j.ijrobp.2009.11.004 10.1002/1097-0142(19820315)49:61308::AID-CNCR28204906393.0.CO;2-G 10.1016/j.brachy.2006.09.002 10.1016/0360-3016(89)90366-0 10.1016/S0360-3016(02)03019-5 10.1016/S0360-3016(98)00028-5 10.1006/gyno.1998.5032 10.1016/S0360-3016(98)00522-7 10.1016/j.ijrobp.2013.08.008 10.1016/0360-3016(88)90111-3 10.1016/j.prro.2012.12.005 10.1006/gyno.1997.4722 10.1016/S0360-3016(98)00453-2 10.1120/jacmp.v14i1.4098 10.1016/S0360-3016(00)00497-1 |
| ContentType | Journal Article |
| Copyright | Copyright © 2015 Shin, Duckworth, Cooper, Curtin, Schiff, DeWyngaert and Lymberis. 2015 Shin, Duckworth, Cooper, Curtin, Schiff, DeWyngaert and Lymberis |
| Copyright_xml | – notice: Copyright © 2015 Shin, Duckworth, Cooper, Curtin, Schiff, DeWyngaert and Lymberis. 2015 Shin, Duckworth, Cooper, Curtin, Schiff, DeWyngaert and Lymberis |
| DBID | AAYXX CITATION NPM 7X8 5PM DOA |
| DOI | 10.3389/fonc.2015.00201 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals (DOAJ) |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 2234-943X |
| ExternalDocumentID | oai_doaj_org_article_07527b34311c4a819f90820d9638408e PMC4568766 26442213 10_3389_fonc_2015_00201 |
| Genre | Journal Article |
| GroupedDBID | 53G 5VS 9T4 AAFWJ AAKDD AAYXX ACGFO ACGFS ADBBV ADRAZ AFPKN ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BCNDV CITATION DIK EBS EJD EMOBN GROUPED_DOAJ GX1 HYE KQ8 M48 M~E OK1 PGMZT RNS RPM ACXDI IPNFZ NPM RIG 7X8 5PM |
| ID | FETCH-LOGICAL-c459t-8cbc30306163d3868a2aef2eb5da0073906a5182b476d7e021e28dcdf20e20413 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 7 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000365132500001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 2234-943X |
| IngestDate | Fri Oct 03 12:27:39 EDT 2025 Thu Aug 21 13:57:41 EDT 2025 Fri Sep 05 13:18:18 EDT 2025 Thu Apr 03 07:00:11 EDT 2025 Tue Nov 18 22:02:42 EST 2025 Sat Nov 29 04:56:59 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | toxicity single-channel applicator interstitial implant multi-channel vaginal applicator |
| Language | English |
| License | This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c459t-8cbc30306163d3868a2aef2eb5da0073906a5182b476d7e021e28dcdf20e20413 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: William Small Jr., Loyola University Chicago, USA Specialty section: This article was submitted to Radiation Oncology, a section of the journal Frontiers in Oncology Reviewed by: Perry Johnson, University of Miami, USA; John C. Roeske, Loyola University Medical Center, USA |
| OpenAccessLink | https://doaj.org/article/07527b34311c4a819f90820d9638408e |
| PMID | 26442213 |
| PQID | 1720447256 |
| PQPubID | 23479 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_07527b34311c4a819f90820d9638408e pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568766 proquest_miscellaneous_1720447256 pubmed_primary_26442213 crossref_citationtrail_10_3389_fonc_2015_00201 crossref_primary_10_3389_fonc_2015_00201 |
| PublicationCentury | 2000 |
| PublicationDate | 2015-09-14 |
| PublicationDateYYYYMMDD | 2015-09-14 |
| PublicationDate_xml | – month: 09 year: 2015 text: 2015-09-14 day: 14 |
| PublicationDecade | 2010 |
| PublicationPlace | Switzerland |
| PublicationPlace_xml | – name: Switzerland |
| PublicationTitle | Frontiers in oncology |
| PublicationTitleAlternate | Front Oncol |
| PublicationYear | 2015 |
| Publisher | Frontiers Media S.A |
| Publisher_xml | – name: Frontiers Media S.A |
| References | Beriwal (B7) 2006; 5 Park (B13) 2013; 87 Richardson (B16) 2010; 78 Poulsen (B5) 1988; 15 Tanderup (B12) 2004; 70 Iftimia (B15) 2013; 14 Zhou (B18) 2014; 4 Tewari (B19) 1999; 74 Demanes (B11) 1999; 44 Perez (B4) 1982; 49 Nag (B9) 1998; 70 Nag (B3) 2000; 48 Wylie (B6) 2000; 77 Nag (B10) 2002; 54 Gloi (B14) 2014; 15 Gupta (B21) 1999; 43 Charra (B20) 1998; 40 Nag (B8) 1997; 66 Au (B17) 2003; 67 Hart (B1) 1998; 41 Kuten (B2) 1989; 17 2745204 - Int J Radiat Oncol Biol Phys. 1989 Jul;17(1):29-34 10192355 - Int J Radiat Oncol Biol Phys. 1999 Mar 15;43(5):1055-60 9588911 - Int J Radiat Oncol Biol Phys. 1998 Apr 1;41(1):7-11 12419443 - Int J Radiat Oncol Biol Phys. 2002 Nov 15;54(4):1153-9 9457831 - Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):421-6 6277462 - Cancer. 1982 Mar 15;49(6):1308-15 12758243 - Radiother Oncol. 2003 Apr;67(1):77-85 15036856 - Radiother Oncol. 2004 Jan;70(1):81-5 11020575 - Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):779-90 10739692 - Gynecol Oncol. 2000 Apr;77(1):66-72 3182320 - Int J Radiat Oncol Biol Phys. 1988 Oct;15(4):809-13 24138921 - Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):840-6 23318396 - J Appl Clin Med Phys. 2013 Jan 07;14(1):4098 9234914 - Gynecol Oncol. 1997 Jul;66(1):16-9 10219816 - Int J Radiat Oncol Biol Phys. 1999 Apr 1;44(1):211-9 24621419 - Pract Radiat Oncol. 2014 Jan-Feb;4(1):20-6 9698469 - Gynecol Oncol. 1998 Jul;70(1):27-32 20395068 - Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):276-9 24423857 - J Appl Clin Med Phys. 2014 Jan 06;15(1):4581 17118313 - Brachytherapy. 2006 Oct-Dec;5(4):218-22 10479502 - Gynecol Oncol. 1999 Sep;74(3):416-22 |
| References_xml | – volume: 70 start-page: 81 issue: 1 year: 2004 ident: B12 article-title: Multi-channel intracavitary vaginal brachytherapy using three-dimensional optimization of source geometry publication-title: Radiother Oncol doi: 10.1016/j.radonc.2003.11.006 – volume: 77 start-page: 66 issue: 1 year: 2000 ident: B6 article-title: Results of radical radiotherapy for recurrent endometrial cancer publication-title: Gynecol Oncol doi: 10.1006/gyno.2000.5727 – volume: 15 start-page: 4581 issue: 1 year: 2014 ident: B14 article-title: First clinical implementation of the Capri applicator publication-title: J Appl Clin Med Phys doi: 10.1120/jacmp.v15i1.4581 – volume: 74 start-page: 416 issue: 3 year: 1999 ident: B19 article-title: Interstitial brachytherapy for vaginal recurrences of endometrial carcinoma publication-title: Gynecol Oncol doi: 10.1006/gyno.1999.5487 – volume: 67 start-page: 77 issue: 1 year: 2003 ident: B17 article-title: The irradiation tolerance dose of the proximal vagina publication-title: Radiother Oncol doi: 10.1016/S0167-8140(02)00384-5 – volume: 40 start-page: 421 issue: 2 year: 1998 ident: B20 article-title: Outcome of treatment of upper third vaginal recurrences of cervical and endometrial carcinomas with interstitial brachytherapy publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(97)00576-2 – volume: 78 start-page: 276 issue: 1 year: 2010 ident: B16 article-title: Dosimetric effects of air pockets around high-dose rate brachytherapy vaginal cylinders publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2009.11.004 – volume: 49 start-page: 1308 issue: 6 year: 1982 ident: B4 article-title: Long-term follow-up in radiation therapy of carcinoma of the vagina publication-title: Cancer doi: 10.1002/1097-0142(19820315)49:61308::AID-CNCR28204906393.0.CO;2-G – volume: 5 start-page: 218 issue: 4 year: 2006 ident: B7 article-title: High-dose-rate interstitial brachytherapy for gynecologic malignancies publication-title: Brachytherapy doi: 10.1016/j.brachy.2006.09.002 – volume: 17 start-page: 29 issue: 1 year: 1989 ident: B2 article-title: Results of radiotherapy in recurrent endometrial carcinoma: a retrospective analysis of 51 patients publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/0360-3016(89)90366-0 – volume: 54 start-page: 1153 issue: 4 year: 2002 ident: B10 article-title: Interstitial brachytherapy for salvage treatment of vaginal recurrences in previously unirradiated endometrial cancer patients publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(02)03019-5 – volume: 41 start-page: 7 issue: 1 year: 1998 ident: B1 article-title: Radiation therapy for endometrial cancer in patients treated for postoperative recurrence publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(98)00028-5 – volume: 70 start-page: 27 issue: 1 year: 1998 ident: B9 article-title: Interstitial brachytherapy in the management of primary carcinoma of the cervix and vagina publication-title: Gynecol Oncol doi: 10.1006/gyno.1998.5032 – volume: 43 start-page: 1055 issue: 5 year: 1999 ident: B21 article-title: Iridium-192 transperineal interstitial brachytherapy for locally advanced or recurrent gynecological malignancies publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(98)00522-7 – volume: 87 start-page: 840 issue: 4 year: 2013 ident: B13 article-title: Dosimetric comparison of 3-dimensional planning techniques using an intravaginal multichannel balloon applicator for high-dose-rate gynecologic brachytherapy publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2013.08.008 – volume: 15 start-page: 809 issue: 4 year: 1988 ident: B5 article-title: The salvage of recurrent endometrial carcinoma in the vagina and pelvis publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/0360-3016(88)90111-3 – volume: 4 start-page: 20 issue: 1 year: 2014 ident: B18 article-title: Single or multi-channel vaginal cuff high-dose-rate brachytherapy: is replanning necessary prior to each fraction publication-title: Pract Radiat Oncol doi: 10.1016/j.prro.2012.12.005 – volume: 66 start-page: 16 issue: 1 year: 1997 ident: B8 article-title: Perineal template interstitial brachytherapy salvage for recurrent endometrial adenocarcinoma metastatic to the vagina publication-title: Gynecol Oncol doi: 10.1006/gyno.1997.4722 – volume: 44 start-page: 211 issue: 1 year: 1999 ident: B11 article-title: The use and advantages of a multichannel vaginal cylinder in high-dose-rate brachytherapy publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(98)00453-2 – volume: 14 start-page: 4098 issue: 1 year: 2013 ident: B15 article-title: Treatment planning methodology for the Miami multichannel applicator following the American brachytherapy society recently published guidelines: the lahey clinic experience publication-title: J Appl Clin Med Phys doi: 10.1120/jacmp.v14i1.4098 – volume: 48 start-page: 779 issue: 3 year: 2000 ident: B3 article-title: The American brachytherapy society recommendations for high-dose-rate brachytherapy for carcinoma of the endometrium publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(00)00497-1 – reference: 12758243 - Radiother Oncol. 2003 Apr;67(1):77-85 – reference: 24138921 - Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):840-6 – reference: 9234914 - Gynecol Oncol. 1997 Jul;66(1):16-9 – reference: 15036856 - Radiother Oncol. 2004 Jan;70(1):81-5 – reference: 9588911 - Int J Radiat Oncol Biol Phys. 1998 Apr 1;41(1):7-11 – reference: 23318396 - J Appl Clin Med Phys. 2013 Jan 07;14(1):4098 – reference: 20395068 - Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):276-9 – reference: 24621419 - Pract Radiat Oncol. 2014 Jan-Feb;4(1):20-6 – reference: 10479502 - Gynecol Oncol. 1999 Sep;74(3):416-22 – reference: 24423857 - J Appl Clin Med Phys. 2014 Jan 06;15(1):4581 – reference: 10192355 - Int J Radiat Oncol Biol Phys. 1999 Mar 15;43(5):1055-60 – reference: 11020575 - Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):779-90 – reference: 10739692 - Gynecol Oncol. 2000 Apr;77(1):66-72 – reference: 6277462 - Cancer. 1982 Mar 15;49(6):1308-15 – reference: 9698469 - Gynecol Oncol. 1998 Jul;70(1):27-32 – reference: 3182320 - Int J Radiat Oncol Biol Phys. 1988 Oct;15(4):809-13 – reference: 12419443 - Int J Radiat Oncol Biol Phys. 2002 Nov 15;54(4):1153-9 – reference: 2745204 - Int J Radiat Oncol Biol Phys. 1989 Jul;17(1):29-34 – reference: 10219816 - Int J Radiat Oncol Biol Phys. 1999 Apr 1;44(1):211-9 – reference: 9457831 - Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):421-6 – reference: 17118313 - Brachytherapy. 2006 Oct-Dec;5(4):218-22 |
| SSID | ssj0000650103 |
| Score | 2.07381 |
| Snippet | Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to... Introduction: Evaluate use of novel multi-channel applicator (MC) CapriTM to improve vaginal disease coverage achievable by single-channel applicator (SC) and... |
| SourceID | doaj pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 201 |
| SubjectTerms | CapriTM Interstitial implant Multi-channel vaginal applicator Oncology Simultaneous integrated boost single-channel applicator Toxicity |
| Title | Use of a Flexible Inflatable Multi-Channel Applicator for Vaginal Brachytherapy in the Management of Gynecologic Cancer |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/26442213 https://www.proquest.com/docview/1720447256 https://pubmed.ncbi.nlm.nih.gov/PMC4568766 https://doaj.org/article/07527b34311c4a819f90820d9638408e |
| Volume | 5 |
| WOSCitedRecordID | wos000365132500001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2234-943X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000650103 issn: 2234-943X databaseCode: DOA dateStart: 20110101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2234-943X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000650103 issn: 2234-943X databaseCode: M~E dateStart: 20110101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELagQogL4t1AqYzEgUto4jgb75FWXUCiFQeK9hb5MVZXWjkouwXthd_OjJ3d7qKiXrhEUZ6WZ-Lvm9jzDWNvjS5qW0GRO11WuZTS5wZZRg5OKnDKeWliovCX5vxcTafjr1ulvmhNWJIHTh13hJAmGlMhzpVWasQvT0W6C0eOIwsFNPoi69kKptIYXFMBg6Tlg1HY-Mh3gRQLy_gLZSgBs4ahqNZ_E8X8e6XkFvRMHrGHA2fkH1JbH7M7EJ6w-2fDrPhT9utiAbzzXPMJyVuaOfDPwc_1ktKieEyxzSmLIAA-ZJiw7nqOdJV_17EsFj_utb1cpWSsFZ8Fjrv8emkMPf3jKoBNQyU_IV_pn7GLyem3k0_5UFAht7IeL3Nlja0oSEAS5io1Ulpo8AJM7XScsitGusaAw8hm5BpA-AehnHVeFCAKhLvnbC90AfYZH3urkHwVzgoS6PEaLWItCZSBMoj5GXu_7t_WDmrjVPRi3mLUQQZpySAtGaSNBsnYu80NP5LQxr8vPSaDbS4jhex4AP2mHfymvc1vMvZmbe4WvyiaJtEBuqtFW1LdHtkgF8zYi2T-zauIPgpRVhlrdhxjpy27Z8LsMqp2I1NF5Bm9_B-Nf8UeUHfQupVSHrC9ZX8Fr9k9-3M5W_SH7G4zVYfxg8Dt2e_TP-wYDm0 |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Use+of+a+Flexible+Inflatable+Multi-Channel+Applicator+for+Vaginal+Brachytherapy+in+the+Management+of+Gynecologic+Cancer&rft.jtitle=Frontiers+in+oncology&rft.au=Samuel+M+Shin&rft.au=Tamara+L+Duckworth&rft.au=Benjamin+Thomas+Cooper&rft.au=John+P+Curtin&rft.date=2015-09-14&rft.pub=Frontiers+Media+S.A&rft.eissn=2234-943X&rft.volume=5&rft_id=info:doi/10.3389%2Ffonc.2015.00201&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_07527b34311c4a819f90820d9638408e |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2234-943X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2234-943X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2234-943X&client=summon |