Effects of Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Their Combination on Endothelial Glycocalyx, Arterial Function, and Myocardial Work Index in Patients With Type 2 Diabetes Mellitus After 12‐Month Treatment

Background We investigated the effects of insulin, glucagon-like peptide-1 receptor agonists (GLP-1RA), sodium-glucose cotransporter-2 inhibitors (SGLT-2i), and their combination on vascular and cardiac function of patients with type 2 diabetes mellitus. Methods and Results A total of 160 patients w...

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Bibliographic Details
Published in:	Journal of the American Heart Association Vol. 9; no. 9; p. e015716
Main Authors:	Ikonomidis, Ignatios, Pavlidis, George, Thymis, John, Birba, Dionysia, Kalogeris, Aimilianos, Kousathana, Foteini, Kountouri, Aikaterini, Balampanis, Konstantinos, Parissis, John, Andreadou, Ioanna, Katogiannis, Konstantinos, Dimitriadis, George, Bamias, Aristotelis, Iliodromitis, Efstathios, Lambadiari, Vaia
Format:	Journal Article
Language:	English
Published:	England John Wiley and Sons Inc 05.05.2020 Wiley
Subjects:	Adult Aged Arterial Pressure - drug effects arterial stiffness Arteries - drug effects Arteries - physiopathology Benzhydryl Compounds - adverse effects Benzhydryl Compounds - therapeutic use Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Drug Therapy, Combination Endothelial Cells - drug effects Endothelial Cells - metabolism endothelial glycocalyx Female Glucagon-Like Peptide-1 Receptor - agonists Glucosides - adverse effects Glucosides - therapeutic use Glycocalyx - drug effects Glycocalyx - metabolism Greece Humans Incretins - adverse effects Incretins - therapeutic use Insulin - therapeutic use left ventricular function Liraglutide - adverse effects Liraglutide - therapeutic use Male Metformin - therapeutic use Middle Aged Original Research Recovery of Function Sodium-Glucose Transporter 2 Inhibitors - adverse effects Sodium-Glucose Transporter 2 Inhibitors - therapeutic use sodium‐glucose cotransporter‐2 inhibitors Time Factors Treatment Outcome Vascular Stiffness - drug effects Ventricular Function, Left - drug effects Greece arterial stiffness glucagon‐like peptide‐1 receptor agonists endothelial glycocalyx sodium‐glucose cotransporter‐2 inhibitors left ventricular function
ISSN:	2047-9980, 2047-9980
Online Access:	Get full text
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