Antagonism between FOXO and MYC Regulates Cellular Powerhouse

Alterations in cellular metabolism are a key feature of the transformed phenotype. Enhanced macromolecule synthesis is a prerequisite for rapid proliferation but may also contribute to induction of angiogenesis, metastasis formation, and tumor progression, thereby leading to a poorer clinical outcom...

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Bibliographic Details

Published in:	Frontiers in oncology Vol. 3; p. 96
Main Authors:	Peck, Barrie, Ferber, Emma C., Schulze, Almut
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 01.01.2013
Subjects:	Cancer HIF hypoxia Metabolism Mitochondria Oncology ROS FOXO hypoxia HIF MYC mitochondria ROS cancer metabolism
ISSN:	2234-943X, 2234-943X
Online Access:	Get full text
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