Colorectal cancer statistics, 2023

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population‐based cancer registries and mortality from the National Center for Health Statistics. In 20...

Full description

Saved in:

Bibliographic Details
Published in:	CA: a cancer journal for clinicians Vol. 73; no. 3; pp. 233 - 254
Main Authors:	Siegel, Rebecca L., Wagle, Nikita Sandeep, Cercek, Andrea, Smith, Robert A., Jemal, Ahmedin
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.05.2023
Subjects:	American Cancer Society Cancer colon and rectum neoplasms Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Diagnosis early‐onset colorectal cancer epidemiology health disparities Humans Incidence Mortality Native North Americans Rectal Neoplasms screening and early detection Statistics United States - epidemiology United States epidemiology health disparities screening and early detection colon and rectum neoplasms early-onset colorectal cancer
ISSN:	0007-9235, 1542-4863, 1542-4863
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population‐based cancer registries and mortality from the National Center for Health Statistics. In 2023, approximately 153,020 individuals will be diagnosed with CRC and 52,550 will die from the disease, including 19,550 cases and 3750 deaths in individuals younger than 50 years. The decline in CRC incidence slowed from 3%–4% annually during the 2000s to 1% annually during 2011–2019, driven partly by an increase in individuals younger than 55 years of 1%–2% annually since the mid‐1990s. Consequently, the proportion of cases among those younger than 55 years increased from 11% in 1995 to 20% in 2019. Incidence since circa 2010 increased in those younger than 65 years for regional‐stage disease by about 2%–3% annually and for distant‐stage disease by 0.5%–3% annually, reversing the overall shift to earlier stage diagnosis that occurred during 1995 through 2005. For example, 60% of all new cases were advanced in 2019 versus 52% in the mid‐2000s and 57% in 1995, before widespread screening. There is also a shift to left‐sided tumors, with the proportion of rectal cancer increasing from 27% in 1995 to 31% in 2019. CRC mortality declined by 2% annually from 2011–2020 overall but increased by 0.5%–3% annually in individuals younger than 50 years and in Native Americans younger than 65 years. In summary, despite continued overall declines, CRC is rapidly shifting to diagnosis at a younger age, at a more advanced stage, and in the left colon/rectum. Progress against CRC could be accelerated by uncovering the etiology of rising incidence in generations born since 1950 and increasing access to high‐quality screening and treatment among all populations, especially Native Americans.
AbstractList	Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population-based cancer registries and mortality from the National Center for Health Statistics. In 2023, approximately 153,020 individuals will be diagnosed with CRC and 52,550 will die from the disease, including 19,550 cases and 3750 deaths in individuals younger than 50 years. The decline in CRC incidence slowed from 3%-4% annually during the 2000s to 1% annually during 2011-2019, driven partly by an increase in individuals younger than 55 years of 1%-2% annually since the mid-1990s. Consequently, the proportion of cases among those younger than 55 years increased from 11% in 1995 to 20% in 2019. Incidence since circa 2010 increased in those younger than 65 years for regional-stage disease by about 2%-3% annually and for distant-stage disease by 0.5%-3% annually, reversing the overall shift to earlier stage diagnosis that occurred during 1995 through 2005. For example, 60% of all new cases were advanced in 2019 versus 52% in the mid-2000s and 57% in 1995, before widespread screening. There is also a shift to left-sided tumors, with the proportion of rectal cancer increasing from 27% in 1995 to 31% in 2019. CRC mortality declined by 2% annually from 2011-2020 overall but increased by 0.5%-3% annually in individuals younger than 50 years and in Native Americans younger than 65 years. In summary, despite continued overall declines, CRC is rapidly shifting to diagnosis at a younger age, at a more advanced stage, and in the left colon/rectum. Progress against CRC could be accelerated by uncovering the etiology of rising incidence in generations born since 1950 and increasing access to high-quality screening and treatment among all populations, especially Native Americans. Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population-based cancer registries and mortality from the National Center for Health Statistics. In 2023, approximately 153,020 individuals will be diagnosed with CRC and 52,550 will die from the disease, including 19,550 cases and 3750 deaths in individuals younger than 50 years. The decline in CRC incidence slowed from 3%-4% annually during the 2000s to 1% annually during 2011-2019, driven partly by an increase in individuals younger than 55 years of 1%-2% annually since the mid-1990s. Consequently, the proportion of cases among those younger than 55 years increased from 11% in 1995 to 20% in 2019. Incidence since circa 2010 increased in those younger than 65 years for regional-stage disease by about 2%-3% annually and for distant-stage disease by 0.5%-3% annually, reversing the overall shift to earlier stage diagnosis that occurred during 1995 through 2005. For example, 60% of all new cases were advanced in 2019 versus 52% in the mid-2000s and 57% in 1995, before widespread screening. There is also a shift to left-sided tumors, with the proportion of rectal cancer increasing from 27% in 1995 to 31% in 2019. CRC mortality declined by 2% annually from 2011-2020 overall but increased by 0.5%-3% annually in individuals younger than 50 years and in Native Americans younger than 65 years. In summary, despite continued overall declines, CRC is rapidly shifting to diagnosis at a younger age, at a more advanced stage, and in the left colon/rectum. Progress against CRC could be accelerated by uncovering the etiology of rising incidence in generations born since 1950 and increasing access to high-quality screening and treatment among all populations, especially Native Americans.Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population-based cancer registries and mortality from the National Center for Health Statistics. In 2023, approximately 153,020 individuals will be diagnosed with CRC and 52,550 will die from the disease, including 19,550 cases and 3750 deaths in individuals younger than 50 years. The decline in CRC incidence slowed from 3%-4% annually during the 2000s to 1% annually during 2011-2019, driven partly by an increase in individuals younger than 55 years of 1%-2% annually since the mid-1990s. Consequently, the proportion of cases among those younger than 55 years increased from 11% in 1995 to 20% in 2019. Incidence since circa 2010 increased in those younger than 65 years for regional-stage disease by about 2%-3% annually and for distant-stage disease by 0.5%-3% annually, reversing the overall shift to earlier stage diagnosis that occurred during 1995 through 2005. For example, 60% of all new cases were advanced in 2019 versus 52% in the mid-2000s and 57% in 1995, before widespread screening. There is also a shift to left-sided tumors, with the proportion of rectal cancer increasing from 27% in 1995 to 31% in 2019. CRC mortality declined by 2% annually from 2011-2020 overall but increased by 0.5%-3% annually in individuals younger than 50 years and in Native Americans younger than 65 years. In summary, despite continued overall declines, CRC is rapidly shifting to diagnosis at a younger age, at a more advanced stage, and in the left colon/rectum. Progress against CRC could be accelerated by uncovering the etiology of rising incidence in generations born since 1950 and increasing access to high-quality screening and treatment among all populations, especially Native Americans. Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC statistics based on incidence from population-based cancer registries and mortality from the National Center for Health Statistics. In 2023, approximately 153,020 individuals will be diagnosed with CRC and 52,550 will die from the disease, including 19,550 cases and 3750 deaths in individuals younger than 50 years. The decline in CRC incidence slowed from 3%–4% annually during the 2000s to 1% annually during 2011–2019, driven partly by an increase in individuals younger than 55 years of 1%–2% annually since the mid-1990s. Consequently, the proportion of cases among those younger than 55 years increased from 11% in 1995 to 20% in 2019. Incidence since circa 2010 increased in those younger than 65 years for regional-stage disease by about 2%–3% annually and for distant-stage disease by 0.5%–3% annually, reversing the overall shift to earlier stage diagnosis that occurred during 1995 through 2005. For example, 60% of all new cases were advanced in 2019 versus 52% in the mid-2000s and 57% in 1995, before widespread screening. There is also a shift to left-sided tumors, with the proportion of rectal cancer increasing from 27% in 1995 to 31% in 2019. CRC mortality declined by 2% annually from 2011–2020 overall but increased by 0.5%–3% annually in individuals younger than 50 years and in Native Americans younger than 65 years. In summary, despite continued overall declines, CRC is rapidly shifting to diagnosis at a younger age, at a more advanced stage, and in the left colon/rectum. Progress against CRC could be accelerated by uncovering the etiology of rising incidence in generations born since 1950 and increasing access to high-quality screening and treatment among all populations, especially Native Americans.
Author	Wagle, Nikita Sandeep Jemal, Ahmedin Siegel, Rebecca L. Cercek, Andrea Smith, Robert A.
Author_xml	– sequence: 1 givenname: Rebecca L. orcidid: 0000-0001-5247-8522 surname: Siegel fullname: Siegel, Rebecca L. email: rebecca.siegel@cancer.org organization: American Cancer Society – sequence: 2 givenname: Nikita Sandeep orcidid: 0000-0003-1337-483X surname: Wagle fullname: Wagle, Nikita Sandeep organization: American Cancer Society – sequence: 3 givenname: Andrea surname: Cercek fullname: Cercek, Andrea organization: Memorial Sloan Kettering Cancer Center – sequence: 4 givenname: Robert A. orcidid: 0000-0003-3344-2238 surname: Smith fullname: Smith, Robert A. organization: American Cancer Society – sequence: 5 givenname: Ahmedin surname: Jemal fullname: Jemal, Ahmedin organization: American Cancer Society
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/36856579$$D View this record in MEDLINE/PubMed
BookMark	eNp90E1LwzAYB_AginvRix9Ahl5E7Mxrkx5H8Q0GXvQc0uwJdHTNTFpk397Wbpch5hICv_9Dnv8Enda-BoSuCJ4zRumjNcbOKZGSnqAxEZwmXKXsFI0xxjLJKBMjNIlxjfu3lOdoxFIlUiGzMbrJfeUD2MZUM2tqC2EWG9OUsSltfJhRTNkFOnOminC5v6fo8_npI39Nlu8vb_limVguMprQlSIOrHSZTDlwyQAkLzIspCgUA94dVshV6iyAoY6vuHKKQOpoiq1Vkk3R3TB3G_xXC7HRmzJaqCpTg2-jplIRSngmVEdvj-jat6HufqepIgRTIUmvrveqLTaw0ttQbkzY6cP2HcADsMHHGMBpW_bL-7oJpqw0wbovWPcF69-Cu8j9UeQw9U9MBvxdVrD7R-p8sciHzA805Ic7
CitedBy_id	crossref_primary_10_1016_j_talanta_2024_126507 crossref_primary_10_3390_ph16081122 crossref_primary_10_3390_ijms25136849 crossref_primary_10_1007_s11033_025_10395_5 crossref_primary_10_1093_jnci_djae124 crossref_primary_10_1016_j_ejphar_2024_176899 crossref_primary_10_1097_MCG_0000000000001940 crossref_primary_10_3390_biomedicines12030602 crossref_primary_10_1002_cam4_70970 crossref_primary_10_1148_rg_230210 crossref_primary_10_1186_s12879_023_08447_x crossref_primary_10_3390_cancers17142310 crossref_primary_10_7759_cureus_76415 crossref_primary_10_1016_j_cellsig_2025_111605 crossref_primary_10_3892_or_2025_8884 crossref_primary_10_1186_s13045_025_01694_2 crossref_primary_10_1016_j_yexcr_2025_114622 crossref_primary_10_1002_VIW_20230100 crossref_primary_10_1080_07853890_2024_2396559 crossref_primary_10_1177_0272989X251334373 crossref_primary_10_1016_j_hpb_2024_07_413 crossref_primary_10_1007_s10278_024_01124_8 crossref_primary_10_1016_j_annonc_2023_12_003 crossref_primary_10_1038_s41598_025_96652_w crossref_primary_10_3390_cancers16193245 crossref_primary_10_1016_j_ijnurstu_2024_104728 crossref_primary_10_1172_JCI169241 crossref_primary_10_1055_a_2604_7345 crossref_primary_10_3389_fphar_2024_1464647 crossref_primary_10_34172_jlms_2023_31 crossref_primary_10_1016_j_ejso_2024_108057 crossref_primary_10_1016_j_phymed_2025_156847 crossref_primary_10_1038_s41467_023_43690_5 crossref_primary_10_1038_s41598_024_52915_6 crossref_primary_10_1097_SLA_0000000000006015 crossref_primary_10_1016_j_intimp_2025_115052 crossref_primary_10_1186_s42269_023_01132_8 crossref_primary_10_1002_cam4_70991 crossref_primary_10_1002_cam4_70994 crossref_primary_10_1016_j_yexcr_2024_114344 crossref_primary_10_1038_s41575_024_00934_z crossref_primary_10_3390_jfb16070229 crossref_primary_10_1097_MLR_0000000000002112 crossref_primary_10_1016_j_esmogo_2024_100054 crossref_primary_10_3390_cancers16010218 crossref_primary_10_1007_s12149_025_02045_4 crossref_primary_10_1097_MCG_0000000000001969 crossref_primary_10_3390_ijtm4030040 crossref_primary_10_2174_0113816128274742231103063738 crossref_primary_10_3390_cells13141195 crossref_primary_10_1186_s12920_024_01893_9 crossref_primary_10_3389_fonc_2025_1621412 crossref_primary_10_1053_j_gastro_2024_02_009 crossref_primary_10_1021_acsabm_5c00567 crossref_primary_10_1016_j_bpg_2024_101891 crossref_primary_10_2147_OTT_S473040 crossref_primary_10_1002_jso_27490 crossref_primary_10_1177_11769351251324545 crossref_primary_10_1016_j_bspc_2024_106928 crossref_primary_10_3390_ijms25147937 crossref_primary_10_1016_j_canlet_2025_217661 crossref_primary_10_3390_diagnostics15131717 crossref_primary_10_3389_fsurg_2023_1308757 crossref_primary_10_36290_xon_2023_037 crossref_primary_10_1007_s12029_024_01085_9 crossref_primary_10_1093_ibd_izae303 crossref_primary_10_1016_j_tranon_2024_102238 crossref_primary_10_1038_s41417_024_00862_9 crossref_primary_10_3389_fcell_2023_1173432 crossref_primary_10_3390_nursrep15090341 crossref_primary_10_3389_fpubh_2024_1465898 crossref_primary_10_1007_s12672_025_02093_2 crossref_primary_10_3390_medicina61010013 crossref_primary_10_1186_s12951_024_02331_9 crossref_primary_10_3390_mti8050040 crossref_primary_10_1055_s_0044_1788602 crossref_primary_10_1016_j_yexcr_2024_114374 crossref_primary_10_1002_advs_202407339 crossref_primary_10_3390_antiox13070866 crossref_primary_10_1186_s13244_024_01886_3 crossref_primary_10_1038_s41698_025_00853_5 crossref_primary_10_1097_MD_0000000000042475 crossref_primary_10_7554_eLife_85264 crossref_primary_10_4251_wjgo_v16_i6_2300 crossref_primary_10_1016_j_intimp_2024_112537 crossref_primary_10_1016_j_soc_2024_11_001 crossref_primary_10_1016_j_ctarc_2024_100807 crossref_primary_10_3390_jimaging9100215 crossref_primary_10_1007_s13042_025_02703_z crossref_primary_10_3389_fonc_2024_1374360 crossref_primary_10_1007_s10620_024_08748_4 crossref_primary_10_7759_cureus_87991 crossref_primary_10_1016_j_jbc_2024_107463 crossref_primary_10_1038_s41598_024_62913_3 crossref_primary_10_1097_SLA_0000000000006443 crossref_primary_10_30699_jambr_33_157_96 crossref_primary_10_2147_DDDT_S457338 crossref_primary_10_7554_eLife_97827_3 crossref_primary_10_1007_s00210_025_03961_y crossref_primary_10_1016_j_ijgc_2024_100013 crossref_primary_10_3390_pharmaceutics15122718 crossref_primary_10_7759_cureus_83124 crossref_primary_10_1371_journal_pone_0322038 crossref_primary_10_1186_s12885_024_12550_w crossref_primary_10_3390_cells13171439 crossref_primary_10_1093_jncics_pkad038 crossref_primary_10_3390_biomedicines12030697 crossref_primary_10_1016_j_radcr_2024_05_031 crossref_primary_10_3892_ol_2024_14823 crossref_primary_10_1016_j_jddst_2024_106349 crossref_primary_10_3390_ijerph20166553 crossref_primary_10_1016_j_tranon_2024_102203 crossref_primary_10_1038_s41598_023_40220_7 crossref_primary_10_3390_nu15214512 crossref_primary_10_3390_nu16040529 crossref_primary_10_3389_fgene_2025_1560172 crossref_primary_10_1002_cam4_6880 crossref_primary_10_1038_s41392_024_01889_y crossref_primary_10_1007_s10620_024_08739_5 crossref_primary_10_1007_s12328_024_02015_9 crossref_primary_10_1038_s44276_024_00045_x crossref_primary_10_3390_cancers17091500 crossref_primary_10_1177_09731296251329683 crossref_primary_10_1007_s00432_024_05805_3 crossref_primary_10_1016_j_snb_2024_135692 crossref_primary_10_1021_acs_molpharmaceut_5c01062 crossref_primary_10_2147_IJN_S466490 crossref_primary_10_31466_kfbd_1608816 crossref_primary_10_3233_THC_241149 crossref_primary_10_1016_j_bioorg_2025_108280 crossref_primary_10_1007_s11033_024_09419_3 crossref_primary_10_3389_fonc_2025_1502014 crossref_primary_10_1007_s11864_024_01282_5 crossref_primary_10_1002_mc_23920 crossref_primary_10_1007_s00261_025_05126_0 crossref_primary_10_1172_jci_insight_189503 crossref_primary_10_1016_j_biocel_2024_106693 crossref_primary_10_1186_s13578_025_01405_x crossref_primary_10_3892_ol_2024_14843 crossref_primary_10_1016_j_puhe_2024_12_011 crossref_primary_10_4251_wjgo_v16_i6_2716 crossref_primary_10_2147_JIR_S500900 crossref_primary_10_1142_S2424905X24500053 crossref_primary_10_1016_j_amjsurg_2025_116350 crossref_primary_10_1016_j_jep_2025_119759 crossref_primary_10_1186_s12935_024_03551_7 crossref_primary_10_3390_cells12151941 crossref_primary_10_1038_s41598_024_80855_8 crossref_primary_10_1002_ddr_70053 crossref_primary_10_1007_s10278_025_01574_8 crossref_primary_10_7759_cureus_73746 crossref_primary_10_1038_s41598_025_91444_8 crossref_primary_10_3892_ijo_2024_5673 crossref_primary_10_1186_s12967_024_06001_0 crossref_primary_10_1186_s12913_025_13185_8 crossref_primary_10_3390_cells13030245 crossref_primary_10_5937_sanamed0_55362 crossref_primary_10_1007_s12672_025_03439_6 crossref_primary_10_1016_j_modpat_2025_100712 crossref_primary_10_3389_fimmu_2025_1630279 crossref_primary_10_1038_s41598_024_76312_1 crossref_primary_10_1002_cam4_6830 crossref_primary_10_1002_smll_202405321 crossref_primary_10_3390_cancers16193287 crossref_primary_10_1080_10520295_2024_2382764 crossref_primary_10_14295_bjs_v4i9_745 crossref_primary_10_1007_s12672_024_01602_z crossref_primary_10_1016_j_actbio_2025_02_013 crossref_primary_10_3390_jcm13082362 crossref_primary_10_1007_s11764_024_01678_0 crossref_primary_10_4251_wjgo_v16_i12_4716 crossref_primary_10_1186_s12964_024_01786_5 crossref_primary_10_1021_acs_jproteome_5c00483 crossref_primary_10_7759_cureus_58135 crossref_primary_10_1186_s43556_024_00212_z crossref_primary_10_1007_s12672_024_01490_3 crossref_primary_10_2147_IJGM_S455546 crossref_primary_10_1016_j_ijbiomac_2024_133112 crossref_primary_10_1007_s00217_025_04855_2 crossref_primary_10_3390_ijms25021097 crossref_primary_10_3748_wjg_v31_i3_98688 crossref_primary_10_3390_app131810156 crossref_primary_10_1016_j_jconrel_2024_01_041 crossref_primary_10_1186_s10020_025_01164_y crossref_primary_10_3390_biomimetics8040370 crossref_primary_10_1016_j_humgen_2024_201358 crossref_primary_10_1039_D5MD00410A crossref_primary_10_3390_ijms25094997 crossref_primary_10_1186_s12920_025_02114_7 crossref_primary_10_1016_j_jep_2024_119007 crossref_primary_10_1016_j_critrevonc_2024_104586 crossref_primary_10_1016_j_bbrep_2025_102024 crossref_primary_10_3923_ijp_2025_231_238 crossref_primary_10_7759_cureus_74600 crossref_primary_10_1002_cam4_70145 crossref_primary_10_3390_cancers16152746 crossref_primary_10_1007_s00464_024_11230_x crossref_primary_10_1016_j_snb_2024_136100 crossref_primary_10_1002_ima_23183 crossref_primary_10_2147_JIR_S462985 crossref_primary_10_3390_cancers17020247 crossref_primary_10_3390_jcm13102810 crossref_primary_10_1200_OA_24_00090 crossref_primary_10_1002_cti2_1495 crossref_primary_10_3389_fonc_2024_1415345 crossref_primary_10_3390_cancers17091568 crossref_primary_10_1080_00365521_2024_2411405 crossref_primary_10_1016_j_asjsur_2025_07_262 crossref_primary_10_1136_gutjnl_2024_332225 crossref_primary_10_1038_s44318_025_00416_1 crossref_primary_10_1007_s10863_024_10039_6 crossref_primary_10_1097_PPO_0000000000000731 crossref_primary_10_1038_s41598_024_72826_w crossref_primary_10_1016_j_prp_2025_156034 crossref_primary_10_7326_ANNALS_24_03246_JC crossref_primary_10_1016_j_jare_2025_09_037 crossref_primary_10_1038_s43856_024_00608_6 crossref_primary_10_14309_ajg_0000000000003301 crossref_primary_10_1016_j_xcrm_2025_102158 crossref_primary_10_3390_cancers16132323 crossref_primary_10_1177_10732748241303650 crossref_primary_10_5306_wjco_v15_i6_667 crossref_primary_10_1002_cac2_12648 crossref_primary_10_1007_s13187_025_02608_z crossref_primary_10_3389_fonc_2023_1340060 crossref_primary_10_1007_s00384_024_04653_4 crossref_primary_10_2174_0118715206356311241128075924 crossref_primary_10_1016_j_clinimag_2024_110241 crossref_primary_10_1136_gutjnl_2024_333533 crossref_primary_10_4103_jrms_jrms_630_23 crossref_primary_10_3390_cancers16030604 crossref_primary_10_1097_MCG_0000000000002024 crossref_primary_10_1177_10732748241274196 crossref_primary_10_1016_j_intimp_2024_112172 crossref_primary_10_1245_s10434_024_15029_x crossref_primary_10_3389_fonc_2025_1524308 crossref_primary_10_12688_f1000research_155021_1 crossref_primary_10_1038_s41401_025_01578_8 crossref_primary_10_1177_11772719251339955 crossref_primary_10_3389_fimmu_2025_1607548 crossref_primary_10_3390_diagnostics15111334 crossref_primary_10_25259_Cytojournal_218_2024 crossref_primary_10_1007_s10552_024_01912_1 crossref_primary_10_3389_fonc_2024_1335670 crossref_primary_10_1158_1055_9965_EPI_24_1549 crossref_primary_10_1007_s11938_025_00469_5 crossref_primary_10_1016_j_phymed_2025_156388 crossref_primary_10_1016_j_cpsurg_2025_101736 crossref_primary_10_1007_s12672_024_01584_y crossref_primary_10_12998_wjcc_v11_i26_6289 crossref_primary_10_3389_fendo_2024_1318416 crossref_primary_10_1200_GO_24_00220 crossref_primary_10_3390_ijms26062698 crossref_primary_10_1007_s11912_023_01430_4 crossref_primary_10_2196_65317 crossref_primary_10_1080_02813432_2024_2432376 crossref_primary_10_3389_fimmu_2024_1400722 crossref_primary_10_3390_md22080357 crossref_primary_10_1245_s10434_025_17717_8 crossref_primary_10_1007_s11547_024_01796_w crossref_primary_10_1186_s12943_024_01962_8 crossref_primary_10_1200_PO_25_00192 crossref_primary_10_3389_fnut_2024_1446660 crossref_primary_10_2478_rjim_2023_0038 crossref_primary_10_1038_s41540_025_00513_1 crossref_primary_10_1093_jnci_djaf095 crossref_primary_10_1002_advs_202310308 crossref_primary_10_1093_jnci_djaf094 crossref_primary_10_62347_WBJL4045 crossref_primary_10_1111_jgh_16713 crossref_primary_10_5306_wjco_v16_i7_107438 crossref_primary_10_1186_s12876_023_02991_1 crossref_primary_10_3390_diagnostics13193126 crossref_primary_10_1080_2162402X_2025_2478850 crossref_primary_10_1016_j_ejso_2024_108532 crossref_primary_10_1186_s41065_025_00412_9 crossref_primary_10_3389_fnut_2025_1595246 crossref_primary_10_7326_M23_1341 crossref_primary_10_1021_acs_jmedchem_5c01561 crossref_primary_10_1038_s41420_025_02365_4 crossref_primary_10_3390_ijms251910367 crossref_primary_10_1002_jbt_70420 crossref_primary_10_1245_s10434_025_18248_y crossref_primary_10_1158_1940_6207_CAPR_23_0239 crossref_primary_10_1186_s12951_025_03143_1 crossref_primary_10_62347_VRJE7714 crossref_primary_10_1002_tox_23993 crossref_primary_10_4251_wjgo_v17_i5_102417 crossref_primary_10_1007_s00384_024_04622_x crossref_primary_10_1007_s00384_024_04644_5 crossref_primary_10_1186_s12957_023_03127_1 crossref_primary_10_1177_08465371241252035 crossref_primary_10_1038_s41575_023_00847_3 crossref_primary_10_3389_or_2025_1589655 crossref_primary_10_3892_ol_2024_14400 crossref_primary_10_1007_s00262_025_04059_3 crossref_primary_10_1016_j_phrs_2024_107556 crossref_primary_10_1200_GO_24_00211 crossref_primary_10_5306_wjco_v15_i10_1280 crossref_primary_10_1200_PO_25_00142 crossref_primary_10_1016_j_cgh_2024_01_044 crossref_primary_10_1177_10732748251330695 crossref_primary_10_1002_imt2_170 crossref_primary_10_1002_oby_24314 crossref_primary_10_14309_ajg_0000000000003391 crossref_primary_10_3390_cells13141221 crossref_primary_10_7759_cureus_68881 crossref_primary_10_1016_j_cgh_2023_09_006 crossref_primary_10_3390_ijms25042032 crossref_primary_10_3390_pharmaceutics16020223 crossref_primary_10_1002_cbdv_202403291 crossref_primary_10_1089_tmj_2023_0605 crossref_primary_10_1016_j_jss_2024_12_046 crossref_primary_10_1038_s43018_024_00823_z crossref_primary_10_3390_jcm13237018 crossref_primary_10_1007_s00384_023_04451_4 crossref_primary_10_1186_s12967_024_04983_5 crossref_primary_10_1186_s43094_023_00557_2 crossref_primary_10_3389_fgene_2025_1443876 crossref_primary_10_1002_fsn3_70794 crossref_primary_10_1186_s12964_024_01582_1 crossref_primary_10_3389_fonc_2024_1468279 crossref_primary_10_1007_s11606_023_08513_9 crossref_primary_10_1016_j_gene_2024_149099 crossref_primary_10_1111_ans_19221 crossref_primary_10_1136_jcp_2024_209878 crossref_primary_10_4103_jcrt_jcrt_1742_24 crossref_primary_10_3390_jcm13185616 crossref_primary_10_4240_wjgs_v17_i4_101066 crossref_primary_10_1038_s41598_024_76155_w crossref_primary_10_3390_cancers17030427 crossref_primary_10_1016_j_drudis_2024_104005 crossref_primary_10_2147_DDDT_S511406 crossref_primary_10_1001_jamaoncol_2025_1361 crossref_primary_10_1016_j_ijnurstu_2025_105100 crossref_primary_10_2147_CMAR_S464831 crossref_primary_10_1002_adbi_202400293 crossref_primary_10_2478_acb_2023_0004 crossref_primary_10_3389_fimmu_2025_1536545 crossref_primary_10_1097_DCR_0000000000003261 crossref_primary_10_3389_fonc_2025_1564375 crossref_primary_10_1038_s41388_023_02883_4 crossref_primary_10_3390_cells12121657 crossref_primary_10_1177_10781552241265058 crossref_primary_10_1016_j_cgh_2024_01_001 crossref_primary_10_1002_wjs_70036 crossref_primary_10_1016_j_phymed_2024_155612 crossref_primary_10_1038_s41598_024_69436_x crossref_primary_10_1056_NEJMoa2304714 crossref_primary_10_7759_cureus_76462 crossref_primary_10_1038_s41522_024_00520_w crossref_primary_10_1097_MD_0000000000040230 crossref_primary_10_1177_00031348251356746 crossref_primary_10_1007_s00261_025_04826_x crossref_primary_10_1016_j_bj_2024_100769 crossref_primary_10_1172_JCI180802 crossref_primary_10_1097_AS9_0000000000000499 crossref_primary_10_1016_j_device_2024_100422 crossref_primary_10_1097_MCG_0000000000002042 crossref_primary_10_3389_fphar_2025_1537095 crossref_primary_10_1097_MCG_0000000000002047 crossref_primary_10_25259_Cytojournal_2_2025 crossref_primary_10_1007_s00259_024_06731_9 crossref_primary_10_1097_PAI_0000000000001183 crossref_primary_10_1016_j_bioadv_2023_213556 crossref_primary_10_1089_cbr_2024_0162 crossref_primary_10_1016_j_clcc_2024_07_002 crossref_primary_10_1007_s12029_025_01247_3 crossref_primary_10_7759_cureus_54210 crossref_primary_10_1111_acel_14152 crossref_primary_10_1177_17562848251327167 crossref_primary_10_3390_life13112198 crossref_primary_10_1038_s41698_025_00978_7 crossref_primary_10_3892_ol_2023_14006 crossref_primary_10_1186_s12967_025_06785_9 crossref_primary_10_1016_j_ijbiomac_2024_139345 crossref_primary_10_3892_etm_2024_12510 crossref_primary_10_3892_ol_2024_14494 crossref_primary_10_52601_bpr_2024_240055 crossref_primary_10_3390_ijms25074022 crossref_primary_10_1007_s00384_024_04724_6 crossref_primary_10_1186_s13148_024_01735_6 crossref_primary_10_1080_14756366_2023_2295241 crossref_primary_10_1016_j_prp_2024_155786 crossref_primary_10_1097_MCG_0000000000002065 crossref_primary_10_1002_jim4_16 crossref_primary_10_1093_jnci_djae176 crossref_primary_10_3390_cells13110951 crossref_primary_10_1002_cnr2_2012 crossref_primary_10_1002_cnr2_70263 crossref_primary_10_1093_carcin_bgae057 crossref_primary_10_1016_j_tranon_2023_101828 crossref_primary_10_1208_s12249_024_02759_0 crossref_primary_10_3389_fnut_2024_1425317 crossref_primary_10_1002_cam4_7382 crossref_primary_10_1177_14574969241282543 crossref_primary_10_1093_bjsopen_zraf024 crossref_primary_10_1002_ijc_35294 crossref_primary_10_1093_jnci_djae244 crossref_primary_10_1007_s00428_024_03974_7 crossref_primary_10_1097_MD_0000000000037827 crossref_primary_10_3390_cancers16020398 crossref_primary_10_3390_cancers16193376 crossref_primary_10_1038_s41416_025_02994_7 crossref_primary_10_1002_cam4_70851 crossref_primary_10_5306_wjco_v15_i7_811 crossref_primary_10_1007_s00423_024_03416_7 crossref_primary_10_1007_s11010_024_05116_8 crossref_primary_10_1016_j_ijbiomac_2024_138342 crossref_primary_10_1186_s12935_025_03798_8 crossref_primary_10_1007_s00384_024_04790_w crossref_primary_10_1080_17501911_2024_2387528 crossref_primary_10_3389_fimmu_2024_1454823 crossref_primary_10_1007_s10552_024_01874_4 crossref_primary_10_1186_s43058_024_00591_y crossref_primary_10_7759_cureus_76557 crossref_primary_10_1097_MS9_0000000000002829 crossref_primary_10_1136_flgastro_2024_103023 crossref_primary_10_1111_jgh_16466 crossref_primary_10_3389_fonc_2023_1278282 crossref_primary_10_1038_s42003_024_06993_x crossref_primary_10_1007_s12011_024_04206_4 crossref_primary_10_1016_j_cbi_2024_111063 crossref_primary_10_1016_j_isci_2024_109676 crossref_primary_10_1002_mnfr_70113 crossref_primary_10_3389_fonc_2023_1236441 crossref_primary_10_1093_jncimonographs_lgad019 crossref_primary_10_3390_jcm13175301 crossref_primary_10_1016_j_canlet_2024_217431 crossref_primary_10_3389_fonc_2023_1288086 crossref_primary_10_3390_jpm13121701 crossref_primary_10_1093_clinchem_hvad198 crossref_primary_10_7326_L24_0012 crossref_primary_10_1080_14737140_2025_2474736 crossref_primary_10_1016_j_celrep_2025_115301 crossref_primary_10_2174_0113816128287232240213105913 crossref_primary_10_7759_cureus_90806 crossref_primary_10_5937_mp75_45064 crossref_primary_10_1080_14737140_2024_2349137 crossref_primary_10_1089_lap_2025_0088 crossref_primary_10_1109_LSENS_2025_3585004 crossref_primary_10_54803_sauhsd_1589761 crossref_primary_10_1007_s12672_025_02081_6 crossref_primary_10_1136_bmj_2024_082452 crossref_primary_10_3389_fimmu_2024_1371584 crossref_primary_10_1007_s10142_023_01208_8 crossref_primary_10_1038_s41598_025_85321_7 crossref_primary_10_1002_cam4_70892 crossref_primary_10_1007_s00044_024_03358_1 crossref_primary_10_3390_jcm14134411 crossref_primary_10_1038_s41467_025_56812_y crossref_primary_10_1080_01635581_2024_2364391 crossref_primary_10_1007_s11033_024_09431_7 crossref_primary_10_3389_fonc_2025_1532624 crossref_primary_10_1186_s43046_025_00311_0 crossref_primary_10_1016_j_intimp_2024_113766 crossref_primary_10_1093_jjco_hyaf080 crossref_primary_10_1007_s10654_024_01120_w crossref_primary_10_1001_jama_2025_10618 crossref_primary_10_3389_fonc_2024_1333702 crossref_primary_10_4251_wjgo_v16_i6_2697 crossref_primary_10_1186_s12951_023_02126_4 crossref_primary_10_3390_jcm13010172 crossref_primary_10_1007_s40200_023_01343_w crossref_primary_10_1016_j_amjsurg_2024_04_003 crossref_primary_10_1016_j_intimp_2024_112424 crossref_primary_10_1155_2023_4354536 crossref_primary_10_1177_07334648251321560 crossref_primary_10_3390_molecules28237684 crossref_primary_10_7717_peerj_18401 crossref_primary_10_1002_jso_28007 crossref_primary_10_1002_jso_28008 crossref_primary_10_1021_acs_jmedchem_4c02314 crossref_primary_10_14309_crj_0000000000001239 crossref_primary_10_1186_s12935_025_03652_x crossref_primary_10_3390_ijms24129990 crossref_primary_10_1016_j_phymed_2024_155786 crossref_primary_10_4236_ojgas_2025_154020 crossref_primary_10_1186_s12885_025_14927_x crossref_primary_10_3390_ijms24129993 crossref_primary_10_4240_wjgs_v16_i7_2096 crossref_primary_10_3892_ol_2025_14991 crossref_primary_10_1016_j_jphotobiol_2024_112919 crossref_primary_10_3389_fcell_2024_1498032 crossref_primary_10_1002_cam4_70424 crossref_primary_10_1158_1078_0432_CCR_24_3964 crossref_primary_10_1186_s13287_025_04456_6 crossref_primary_10_62347_KZDR9031 crossref_primary_10_1007_s12602_024_10405_1 crossref_primary_10_1111_cas_70063 crossref_primary_10_25259_IJPC_332_2023 crossref_primary_10_3390_cancers16051052 crossref_primary_10_1016_j_sajb_2024_06_028 crossref_primary_10_1111_apm_70041 crossref_primary_10_3389_fphar_2025_1541820 crossref_primary_10_1002_cbdv_202402758 crossref_primary_10_1111_ans_70151 crossref_primary_10_3389_fphar_2023_1254918 crossref_primary_10_3389_fonc_2025_1545082 crossref_primary_10_1186_s13561_025_00622_x crossref_primary_10_1002_tox_24426 crossref_primary_10_7759_cureus_93046 crossref_primary_10_3390_biomedicines13051245 crossref_primary_10_1002_cncr_35599 crossref_primary_10_1007_s00330_024_11220_6 crossref_primary_10_3390_microorganisms12091924 crossref_primary_10_1038_s41467_025_58992_z crossref_primary_10_1155_jfbc_8148622 crossref_primary_10_3390_bioengineering11100959 crossref_primary_10_1002_advs_202406962 crossref_primary_10_1051_epjconf_202430910020 crossref_primary_10_1109_ACCESS_2025_3539181 crossref_primary_10_1126_science_adn0327 crossref_primary_10_1002_ddr_70151 crossref_primary_10_1007_s00261_025_04965_1 crossref_primary_10_1002_slct_202500263 crossref_primary_10_1158_1940_6207_CAPR_25_0007 crossref_primary_10_1002_gepi_22590 crossref_primary_10_1007_s00262_024_03896_y crossref_primary_10_1186_s12912_025_03062_4 crossref_primary_10_1177_10732748241256819 crossref_primary_10_1245_s10434_025_16905_w crossref_primary_10_3389_fphar_2024_1377592 crossref_primary_10_1002_cai2_70000 crossref_primary_10_1016_j_jclinepi_2025_111669 crossref_primary_10_3389_fsurg_2023_1251461 crossref_primary_10_1111_codi_70092 crossref_primary_10_3390_app142412063 crossref_primary_10_3389_fonc_2025_1535271 crossref_primary_10_3892_ol_2025_14950 crossref_primary_10_1007_s11044_025_10052_6 crossref_primary_10_3390_cancers16010171 crossref_primary_10_1088_1758_5090_adf099 crossref_primary_10_1002_acm2_70031 crossref_primary_10_1016_j_critrevonc_2025_104714 crossref_primary_10_1245_s10434_025_17266_0 crossref_primary_10_7759_cureus_83230 crossref_primary_10_1177_15330338231185285 crossref_primary_10_2217_imt_2023_0235 crossref_primary_10_1080_07347332_2024_2425679 crossref_primary_10_3390_diagnostics14171888 crossref_primary_10_3389_ebm_2025_10469 crossref_primary_10_1186_s40001_025_03019_y crossref_primary_10_3389_fonc_2025_1529868 crossref_primary_10_1007_s12672_025_02024_1 crossref_primary_10_1016_j_apsb_2024_04_024 crossref_primary_10_1080_20002297_2024_2344278 crossref_primary_10_3389_fonc_2023_1280977 crossref_primary_10_1139_bcb_2024_0218 crossref_primary_10_1007_s00262_024_03665_x crossref_primary_10_1038_s41598_024_58016_8 crossref_primary_10_1016_j_procbio_2024_11_017 crossref_primary_10_1016_j_cpt_2025_06_007 crossref_primary_10_7759_cureus_85866 crossref_primary_10_1007_s00432_024_05804_4 crossref_primary_10_1007_s00464_024_10885_w crossref_primary_10_1111_ejh_14229 crossref_primary_10_1038_s41575_025_01062_y crossref_primary_10_1371_journal_pone_0303494 crossref_primary_10_1016_j_bbcan_2023_189056 crossref_primary_10_1016_j_critrevonc_2025_104775 crossref_primary_10_1016_j_acra_2024_09_008 crossref_primary_10_3892_or_2024_8784 crossref_primary_10_1016_j_clinre_2023_102171 crossref_primary_10_3389_fgene_2024_1292249 crossref_primary_10_3390_jcm13247776 crossref_primary_10_1021_acs_langmuir_5c01514 crossref_primary_10_1038_s41598_025_05807_2 crossref_primary_10_1016_j_acra_2025_02_019 crossref_primary_10_1245_s10434_023_14414_2 crossref_primary_10_2147_JMDH_S493863 crossref_primary_10_3389_fimmu_2025_1631031 crossref_primary_10_3390_cancers16142606 crossref_primary_10_1016_j_biopha_2024_117796 crossref_primary_10_1177_10436596251340394 crossref_primary_10_1002_cam4_6722 crossref_primary_10_1007_s13304_024_01846_y crossref_primary_10_1016_j_biopha_2024_117799 crossref_primary_10_1177_00031348251350981 crossref_primary_10_1007_s11606_025_09706_0 crossref_primary_10_1016_j_critrevonc_2025_104741 crossref_primary_10_1016_j_ejmech_2024_116452 crossref_primary_10_1016_j_cgh_2023_05_033 crossref_primary_10_3390_ijms241210249 crossref_primary_10_1186_s12885_024_12507_z crossref_primary_10_1186_s12951_024_02970_y crossref_primary_10_1038_s41598_024_59398_5 crossref_primary_10_3390_cancers15184442 crossref_primary_10_1016_j_acra_2025_02_046 crossref_primary_10_1016_j_jncc_2024_10_002 crossref_primary_10_3322_caac_21874 crossref_primary_10_1093_tbm_ibaf020 crossref_primary_10_32948_ajpt_2025_01_20 crossref_primary_10_3322_caac_21871 crossref_primary_10_3390_ijms241914815 crossref_primary_10_1007_s00520_024_08390_w crossref_primary_10_1016_j_phymed_2024_155383 crossref_primary_10_62347_OPNG2835 crossref_primary_10_1007_s12032_025_02861_8 crossref_primary_10_1186_s41065_025_00405_8 crossref_primary_10_3390_cancers17010120 crossref_primary_10_1001_jama_2025_7557 crossref_primary_10_1016_j_hoc_2024_04_002 crossref_primary_10_1186_s13045_024_01643_5 crossref_primary_10_1016_j_ejmech_2024_116448 crossref_primary_10_1002_ags3_12829 crossref_primary_10_1007_s11033_025_10225_8 crossref_primary_10_1080_03007995_2025_2529984 crossref_primary_10_3390_toxins16090403 crossref_primary_10_1016_j_glmedi_2024_100163 crossref_primary_10_1016_j_annonc_2024_07_729 crossref_primary_10_1111_codi_70046 crossref_primary_10_3892_ol_2025_15058 crossref_primary_10_1016_j_bbrc_2025_151962 crossref_primary_10_1038_s41598_024_82415_6 crossref_primary_10_1016_j_pop_2024_12_007 crossref_primary_10_1016_j_jbc_2025_108559 crossref_primary_10_18203_2349_2902_isj20252704 crossref_primary_10_3390_biomedicines12102411 crossref_primary_10_1007_s10552_025_01985_6 crossref_primary_10_3389_fonc_2023_1184215 crossref_primary_10_1186_s12943_024_02174_w crossref_primary_10_3389_fnut_2024_1399569 crossref_primary_10_3390_ijms24119295 crossref_primary_10_1007_s12672_024_01321_5 crossref_primary_10_1186_s10020_025_01294_3 crossref_primary_10_1186_s12876_025_03985_x crossref_primary_10_3390_ijms25158094 crossref_primary_10_1038_s41420_024_02249_z crossref_primary_10_1016_j_pathol_2024_11_009 crossref_primary_10_1001_jamasurg_2025_1398 crossref_primary_10_1007_s00432_023_05168_1 crossref_primary_10_25259_JKSUS_222_2024 crossref_primary_10_2196_66960 crossref_primary_10_1186_s12889_025_22800_6 crossref_primary_10_1038_s41419_024_07266_5 crossref_primary_10_1371_journal_pone_0311540 crossref_primary_10_1016_j_gene_2025_149433 crossref_primary_10_1111_1751_2980_70001 crossref_primary_10_1002_deo2_70113 crossref_primary_10_1016_j_gassur_2023_11_003 crossref_primary_10_1007_s44155_024_00102_3 crossref_primary_10_1186_s12967_024_04931_3 crossref_primary_10_1007_s40520_024_02833_4 crossref_primary_10_1002_adhm_202400833 crossref_primary_10_1158_0008_5472_CAN_24_1620 crossref_primary_10_1038_s41419_025_07656_3 crossref_primary_10_3389_fphar_2024_1356708 crossref_primary_10_3390_cancers16111995 crossref_primary_10_3390_cancers16111992 crossref_primary_10_1002_adfm_202405588 crossref_primary_10_1007_s10552_023_01795_8 crossref_primary_10_3390_jcm13020423 crossref_primary_10_1186_s12885_025_14482_5 crossref_primary_10_1007_s00384_023_04581_9 crossref_primary_10_1146_annurev_pharmtox_051920_095416 crossref_primary_10_7717_peerj_19240 crossref_primary_10_1111_andr_13772 crossref_primary_10_3322_caac_21820 crossref_primary_10_1371_journal_pone_0298100 crossref_primary_10_1016_j_ecoenv_2024_117351 crossref_primary_10_1088_2057_1976_ad644e crossref_primary_10_1186_s12893_024_02364_9 crossref_primary_10_1016_j_jmoldx_2024_05_001 crossref_primary_10_1007_s11864_023_01142_8 crossref_primary_10_1177_00031348241244632 crossref_primary_10_1038_s41564_024_01784_w crossref_primary_10_3389_fonc_2024_1373820 crossref_primary_10_1038_s41598_025_05570_4 crossref_primary_10_2147_CMAR_S527441 crossref_primary_10_1080_15548627_2025_2477443 crossref_primary_10_1186_s12876_025_04040_5 crossref_primary_10_1038_s41598_024_60265_6 crossref_primary_10_1111_jgh_16847 crossref_primary_10_1097_GH9_0000000000000512 crossref_primary_10_3390_cells13161314 crossref_primary_10_1007_s00432_025_06092_2 crossref_primary_10_1016_j_gene_2024_148258 crossref_primary_10_1016_j_jconrel_2024_09_047 crossref_primary_10_1016_j_cej_2025_163582 crossref_primary_10_1177_11795549241255651 crossref_primary_10_3389_fpubh_2024_1414361 crossref_primary_10_2174_0113816128291321240329050945 crossref_primary_10_1016_j_bioorg_2025_108344 crossref_primary_10_1038_s41418_024_01418_y crossref_primary_10_1515_ntrev_2025_0167 crossref_primary_10_3389_fimmu_2025_1564213 crossref_primary_10_1038_s41598_024_55967_w crossref_primary_10_3892_ol_2024_14502 crossref_primary_10_1186_s12964_024_01490_4 crossref_primary_10_1038_s41388_025_03302_6 crossref_primary_10_1021_acs_jmedchem_5c01441 crossref_primary_10_3389_fphar_2024_1409683 crossref_primary_10_1111_jgs_19425 crossref_primary_10_3390_ijms25052985 crossref_primary_10_1200_EDBK_25_473618 crossref_primary_10_1007_s00210_025_04274_w crossref_primary_10_1016_j_ijbiomac_2025_142744 crossref_primary_10_1016_j_suronc_2025_102252 crossref_primary_10_1016_j_clinimag_2024_110166 crossref_primary_10_1016_j_cpt_2024_02_002 crossref_primary_10_1186_s12885_024_11937_z crossref_primary_10_1186_s12935_024_03422_1 crossref_primary_10_3892_ol_2025_15030 crossref_primary_10_3390_jcm13082292 crossref_primary_10_1007_s00384_024_04789_3 crossref_primary_10_1038_s41416_024_02787_4 crossref_primary_10_3389_fimmu_2024_1470449 crossref_primary_10_3389_fonc_2025_1500273 crossref_primary_10_1016_j_carpta_2025_100942 crossref_primary_10_3390_cancers16183183 crossref_primary_10_1007_s12668_025_01800_1 crossref_primary_10_1016_j_ejrad_2025_112151 crossref_primary_10_1186_s12967_024_05635_4 crossref_primary_10_3346_jkms_2025_40_e146 crossref_primary_10_3389_fonc_2024_1428942 crossref_primary_10_3390_ijms25126403 crossref_primary_10_1186_s12906_024_04725_6 crossref_primary_10_1080_1354750X_2024_2447089 crossref_primary_10_1016_j_scrs_2024_101022 crossref_primary_10_1186_s13046_025_03422_7 crossref_primary_10_1245_s10434_025_16941_6 crossref_primary_10_1155_bmri_9214337 crossref_primary_10_1186_s12964_024_02016_8 crossref_primary_10_1007_s11101_024_10015_3 crossref_primary_10_3390_biom14070847 crossref_primary_10_1093_nutrit_nuad133 crossref_primary_10_26779_2786_832X_2023_5_54 crossref_primary_10_1007_s12013_024_01430_6 crossref_primary_10_3390_gastroent15020037 crossref_primary_10_1186_s13148_025_01918_9 crossref_primary_10_32604_or_2024_052939 crossref_primary_10_1016_j_canep_2025_102747 crossref_primary_10_1158_1055_9965_EPI_24_1609 crossref_primary_10_1038_s41598_024_73617_z crossref_primary_10_3390_ijerph21020126 crossref_primary_10_1016_j_biopha_2023_115610 crossref_primary_10_3390_pharmaceutics16060803 crossref_primary_10_1038_s41598_024_54658_w crossref_primary_10_4251_wjgo_v16_i5_1683 crossref_primary_10_1111_his_15423 crossref_primary_10_1016_j_scrs_2024_101041 crossref_primary_10_1002_2211_5463_13784 crossref_primary_10_1136_gutjnl_2023_331729 crossref_primary_10_1177_10732748241300653 crossref_primary_10_1371_journal_pone_0303951 crossref_primary_10_1007_s00384_025_04931_9 crossref_primary_10_1186_s12896_024_00882_1 crossref_primary_10_1111_jcmm_18441 crossref_primary_10_1155_2024_6200915 crossref_primary_10_1007_s00520_024_09076_z crossref_primary_10_1016_j_compbiolchem_2025_108349 crossref_primary_10_1007_s10620_025_08861_y crossref_primary_10_1007_s13346_024_01707_6 crossref_primary_10_1007_s00423_024_03460_3 crossref_primary_10_3390_cancers16132464 crossref_primary_10_3390_gidisord6010019 crossref_primary_10_3390_diagnostics14060625 crossref_primary_10_1016_j_surg_2024_09_044 crossref_primary_10_1016_j_focus_2024_100308 crossref_primary_10_1186_s12913_025_12490_6 crossref_primary_10_1016_j_jss_2024_05_036 crossref_primary_10_1097_MD_0000000000039133 crossref_primary_10_34922_AE_2025_38_1_002 crossref_primary_10_1002_ardp_202400628 crossref_primary_10_3389_fimmu_2025_1548635 crossref_primary_10_1002_celc_202300641 crossref_primary_10_1186_s12885_024_12280_z crossref_primary_10_1007_s13304_025_02175_4 crossref_primary_10_1002_advs_202506641 crossref_primary_10_1002_adfm_202409966 crossref_primary_10_3390_cancers15164077 crossref_primary_10_1007_s12672_024_01169_9 crossref_primary_10_1038_s41389_025_00562_5 crossref_primary_10_1097_DCR_0000000000003164 crossref_primary_10_1007_s00464_025_11980_2 crossref_primary_10_2196_50110 crossref_primary_10_1002_1878_0261_13578 crossref_primary_10_1007_s11136_024_03857_z crossref_primary_10_1097_MCG_0000000000002172 crossref_primary_10_1158_2767_9764_CRC_25_0164 crossref_primary_10_1186_s13046_025_03368_w crossref_primary_10_3389_fgene_2025_1545017 crossref_primary_10_3892_mmr_2024_13286 crossref_primary_10_1186_s12885_024_12898_z crossref_primary_10_1007_s13304_025_02286_y crossref_primary_10_1126_scisignal_ads6550 crossref_primary_10_1002_jev2_70088 crossref_primary_10_4103_jfmpc_jfmpc_1344_24 crossref_primary_10_2147_PGPM_S455490 crossref_primary_10_3389_fimmu_2024_1414376 crossref_primary_10_1002_mco2_760 crossref_primary_10_14309_ctg_0000000000000826 crossref_primary_10_1039_D4FO04045G crossref_primary_10_1002_ctm2_70049 crossref_primary_10_1016_j_prp_2024_155429 crossref_primary_10_1186_s12916_024_03662_y crossref_primary_10_1111_codi_16983 crossref_primary_10_1111_phn_13519 crossref_primary_10_1186_s12885_024_12996_y crossref_primary_10_3390_jcm14124106 crossref_primary_10_1002_adma_202502203 crossref_primary_10_3390_life14010126 crossref_primary_10_1093_carcin_bgaf026 crossref_primary_10_1158_0008_5472_CAN_24_0798 crossref_primary_10_1097_DCR_0000000000003189 crossref_primary_10_1007_s00432_024_05986_x crossref_primary_10_3390_ijms241813741 crossref_primary_10_1002_bmc_70198 crossref_primary_10_1016_j_neo_2023_100939 crossref_primary_10_1007_s00432_024_05755_w crossref_primary_10_3389_fphar_2023_1340401 crossref_primary_10_3390_diagnostics14131417 crossref_primary_10_1038_s44355_025_00026_y crossref_primary_10_1186_s12876_025_03607_6 crossref_primary_10_1016_j_phymed_2024_155497 crossref_primary_10_34172_apb_2024_041 crossref_primary_10_1136_bmjopen_2023_072244 crossref_primary_10_1186_s12916_025_04128_5 crossref_primary_10_4251_wjgo_v16_i6_2520 crossref_primary_10_1007_s12664_025_01861_w crossref_primary_10_1038_s41467_025_59139_w crossref_primary_10_1128_msystems_00148_25 crossref_primary_10_1093_jnci_djaf202 crossref_primary_10_1007_s12032_025_02635_2 crossref_primary_10_1093_mutage_geae014 crossref_primary_10_1038_s41746_025_01833_6 crossref_primary_10_3390_ijerph21020170 crossref_primary_10_1186_s12943_024_02135_3 crossref_primary_10_1038_s41416_024_02845_x crossref_primary_10_1007_s00394_024_03499_4 crossref_primary_10_1016_j_bios_2025_117190 crossref_primary_10_1007_s00432_024_06022_8 crossref_primary_10_7759_cureus_66852 crossref_primary_10_1177_10732748251374410 crossref_primary_10_1007_s00432_025_06196_9 crossref_primary_10_1016_j_humpath_2024_105682 crossref_primary_10_1186_s13244_023_01593_5 crossref_primary_10_1186_s12967_025_06863_y crossref_primary_10_3390_molecules29184311 crossref_primary_10_3389_fmicb_2025_1635409 crossref_primary_10_1007_s12029_024_01096_6 crossref_primary_10_1007_s40615_024_02030_z crossref_primary_10_1093_qjmed_hcaf074 crossref_primary_10_1038_s41467_025_59588_3 crossref_primary_10_1016_j_jep_2025_119972 crossref_primary_10_1007_s10353_025_00870_5 crossref_primary_10_1111_cge_14739 crossref_primary_10_3389_fpubh_2024_1319977 crossref_primary_10_3389_fimmu_2025_1626438 crossref_primary_10_3390_cells13191663 crossref_primary_10_3390_medsci12030047 crossref_primary_10_3389_fonc_2024_1457886 crossref_primary_10_1016_j_gene_2024_148752 crossref_primary_10_3389_fonc_2024_1338098 crossref_primary_10_1186_s12967_024_05267_8 crossref_primary_10_7759_cureus_74014 crossref_primary_10_1186_s12885_025_14652_5 crossref_primary_10_1016_j_radcr_2024_06_003 crossref_primary_10_1038_s41598_025_92106_5 crossref_primary_10_1007_s13304_025_02104_5 crossref_primary_10_1080_01635581_2024_2344250 crossref_primary_10_33192_smj_v77i9_274210 crossref_primary_10_1038_s41598_025_04621_0 crossref_primary_10_3390_cancers15235531 crossref_primary_10_1136_bmjopen_2025_099058 crossref_primary_10_3892_ijo_2025_5726 crossref_primary_10_1111_jgh_17012 crossref_primary_10_7759_cureus_69092 crossref_primary_10_1007_s00261_025_04833_y crossref_primary_10_3390_biom15060777 crossref_primary_10_16919_bozoktip_1657875 crossref_primary_10_3390_cancers15133509 crossref_primary_10_3390_ph17070922 crossref_primary_10_7326_AITC202404160 crossref_primary_10_3390_ijms25063178 crossref_primary_10_1016_j_ctrv_2024_102683 crossref_primary_10_1021_acsami_5c10905 crossref_primary_10_1002_imo2_70003 crossref_primary_10_3390_cancers17111854 crossref_primary_10_2147_ITT_S532644 crossref_primary_10_1128_msystems_00734_24 crossref_primary_10_1016_j_acra_2023_12_034 crossref_primary_10_1002_ctm2_70340 crossref_primary_10_1038_s41522_025_00702_0 crossref_primary_10_1038_s41598_024_74299_3 crossref_primary_10_3390_ijms26115111 crossref_primary_10_51847_nyDxRaP7Au crossref_primary_10_1001_jamanetworkopen_2024_36358 crossref_primary_10_4251_wjgo_v16_i8_3496 crossref_primary_10_1049_htl2_12122 crossref_primary_10_1007_s11864_024_01186_4 crossref_primary_10_4240_wjgs_v16_i10_3202 crossref_primary_10_3892_or_2024_8859 crossref_primary_10_1177_10732748251313499 crossref_primary_10_1016_j_biomaterials_2025_123281 crossref_primary_10_3390_cancers16122277 crossref_primary_10_1016_j_ejrad_2024_111459 crossref_primary_10_3390_cancers16030495 crossref_primary_10_1007_s12672_024_01350_0 crossref_primary_10_3390_jcm13010040 crossref_primary_10_1038_s41698_025_00975_w crossref_primary_10_1016_j_surg_2024_06_003 crossref_primary_10_1007_s11864_025_01326_4 crossref_primary_10_3389_fonc_2023_1242193 crossref_primary_10_1186_s12964_024_01771_y crossref_primary_10_1016_j_tranon_2025_102313 crossref_primary_10_3390_cancers16112004 crossref_primary_10_1002_smll_202405508 crossref_primary_10_1186_s12885_024_12321_7 crossref_primary_10_1007_s00384_024_04803_8 crossref_primary_10_3892_or_2024_8840 crossref_primary_10_1136_bmjph_2024_001734 crossref_primary_10_3389_fonc_2025_1586344 crossref_primary_10_1093_jnci_djae340 crossref_primary_10_2174_0122106812372775250207074104 crossref_primary_10_1016_j_ecoenv_2024_116750 crossref_primary_10_4253_wjge_v16_i3_102 crossref_primary_10_25259_JCIS_11_2025 crossref_primary_10_7759_cureus_50431 crossref_primary_10_1186_s12876_025_03932_w crossref_primary_10_1038_s41419_025_07724_8 crossref_primary_10_3390_cancers15143740 crossref_primary_10_1007_s10278_023_00954_2 crossref_primary_10_1016_j_intimp_2024_113683 crossref_primary_10_1093_oncolo_oyaf069 crossref_primary_10_1016_j_ccr_2024_216069 crossref_primary_10_1186_s12935_024_03584_y crossref_primary_10_1002_advs_202417714 crossref_primary_10_3390_diagnostics14101052 crossref_primary_10_70352_scrj_cr_24_0024 crossref_primary_10_7759_cureus_75713 crossref_primary_10_1186_s12876_023_03003_y crossref_primary_10_7759_cureus_45095 crossref_primary_10_1016_j_jconrel_2023_07_005 crossref_primary_10_3748_wjg_v30_i13_1815 crossref_primary_10_1002_1878_0261_13814 crossref_primary_10_1007_s12029_025_01241_9 crossref_primary_10_1002_advs_202405758 crossref_primary_10_3390_cancers15245795 crossref_primary_10_1038_s41417_024_00838_9 crossref_primary_10_1016_j_intimp_2025_114801 crossref_primary_10_1007_s40615_025_02450_5 crossref_primary_10_1360_TB_2024_0571 crossref_primary_10_3390_bios15040231 crossref_primary_10_1007_s00204_024_03702_9 crossref_primary_10_1186_s13046_024_03053_4 crossref_primary_10_1186_s40001_025_02721_1 crossref_primary_10_1002_cam4_71202 crossref_primary_10_1007_s10528_023_10621_4 crossref_primary_10_1016_j_omton_2024_200828 crossref_primary_10_1186_s43088_025_00615_z crossref_primary_10_1177_10732748251357469 crossref_primary_10_3389_fnut_2023_1300330 crossref_primary_10_1007_s00261_025_04886_z crossref_primary_10_4251_wjgo_v16_i3_583 crossref_primary_10_2147_CMAR_S503985 crossref_primary_10_1038_s41416_024_02814_4 crossref_primary_10_1016_j_cellsig_2024_111134 crossref_primary_10_1007_s00270_025_04036_4 crossref_primary_10_3390_medicina60040673 crossref_primary_10_1186_s12880_025_01844_5 crossref_primary_10_1016_j_cej_2025_161104 crossref_primary_10_4251_wjgo_v16_i4_1119 crossref_primary_10_1016_j_isci_2024_110701 crossref_primary_10_1007_s10552_024_01895_z crossref_primary_10_1007_s00464_025_11634_3 crossref_primary_10_3390_diagnostics13203199 crossref_primary_10_29333_ejgm_16745 crossref_primary_10_1200_JCO_24_00220 crossref_primary_10_1007_s00117_025_01453_x crossref_primary_10_1016_j_amepre_2024_10_003 crossref_primary_10_1186_s12876_025_04213_2 crossref_primary_10_3390_cimb46070447 crossref_primary_10_1007_s00384_025_04805_0 crossref_primary_10_3748_wjg_v31_i34_110051 crossref_primary_10_1111_jcmm_70457 crossref_primary_10_1016_j_canlet_2025_217810 crossref_primary_10_3748_wjg_v31_i31_109857 crossref_primary_10_3389_fonc_2024_1514581 crossref_primary_10_2340_1651_226X_2025_43349 crossref_primary_10_1177_21501319241242571 crossref_primary_10_3390_biomedicines13051151 crossref_primary_10_1007_s12672_025_03415_0 crossref_primary_10_1186_s12943_025_02283_0 crossref_primary_10_1186_s13244_024_01795_5 crossref_primary_10_3390_ijtm4040050 crossref_primary_10_4251_wjgo_v17_i4_100678 crossref_primary_10_4251_wjgo_v16_i7_3241 crossref_primary_10_1109_TMI_2024_3510836 crossref_primary_10_1038_s41598_025_03684_3 crossref_primary_10_1002_advs_202500304 crossref_primary_10_1007_s10151_024_02981_9 crossref_primary_10_3389_fphar_2024_1532695 crossref_primary_10_1186_s40364_025_00744_8 crossref_primary_10_1016_j_jddst_2024_106596 crossref_primary_10_1007_s40615_023_01756_6 crossref_primary_10_1177_17588359251356581 crossref_primary_10_1186_s12885_023_11766_6 crossref_primary_10_4236_jbm_2025_139003 crossref_primary_10_1016_j_toxicon_2024_108103 crossref_primary_10_1038_s41598_024_57209_5 crossref_primary_10_1186_s40001_024_01819_2 crossref_primary_10_1080_08998280_2024_2401757 crossref_primary_10_3389_fonc_2024_1349572 crossref_primary_10_3389_fnut_2024_1479800 crossref_primary_10_3389_fonc_2024_1409329 crossref_primary_10_1080_09553002_2024_2435324 crossref_primary_10_3748_wjg_v30_i42_4566 crossref_primary_10_1016_j_csbj_2024_05_051 crossref_primary_10_1016_j_puhe_2024_06_010 crossref_primary_10_3389_fphar_2025_1568339 crossref_primary_10_1186_s12957_023_03108_4 crossref_primary_10_1016_j_gastha_2024_09_007 crossref_primary_10_1080_07853890_2025_2555518 crossref_primary_10_1097_NCC_0000000000001473 crossref_primary_10_1038_s41419_024_07263_8 crossref_primary_10_1186_s12967_024_05423_0 crossref_primary_10_1007_s40199_023_00474_y crossref_primary_10_1126_scirobotics_adt0187 crossref_primary_10_1186_s12964_024_01789_2 crossref_primary_10_1016_j_ejca_2024_114036 crossref_primary_10_3389_fonc_2023_1267838 crossref_primary_10_1038_s41419_024_07036_3 crossref_primary_10_3892_mmr_2024_13384 crossref_primary_10_3390_cancers16244254 crossref_primary_10_3892_mmr_2024_13389 crossref_primary_10_2174_0113816128362419250523061958 crossref_primary_10_1002_ctm2_1730 crossref_primary_10_1093_oncolo_oyae269 crossref_primary_10_3390_epigenomes9020018 crossref_primary_10_1002_cam4_71145 crossref_primary_10_1007_s00464_025_12040_5 crossref_primary_10_1016_j_ctcp_2024_101900 crossref_primary_10_1002_ajim_23582 crossref_primary_10_3390_ijms25105410 crossref_primary_10_1016_j_ejphar_2025_177351 crossref_primary_10_1371_journal_pone_0310327 crossref_primary_10_3389_fbioe_2024_1439883 crossref_primary_10_1371_journal_pone_0307133 crossref_primary_10_3390_cancers17101686 crossref_primary_10_3389_fonc_2023_1253660 crossref_primary_10_1007_s00394_024_03513_9 crossref_primary_10_1093_oncolo_oyae259 crossref_primary_10_1186_s12943_024_02086_9 crossref_primary_10_1186_s13046_024_03204_7 crossref_primary_10_3389_fimmu_2025_1496640 crossref_primary_10_1016_j_mtbio_2025_101768 crossref_primary_10_1111_jgh_16910 crossref_primary_10_1038_s41598_025_85390_8 crossref_primary_10_1038_s41698_024_00689_5 crossref_primary_10_1039_D3BM01952G crossref_primary_10_48130_git_0025_0005 crossref_primary_10_1039_D5NR01337B crossref_primary_10_1200_OP_24_00159 crossref_primary_10_3390_cancers16244237 crossref_primary_10_2147_IJWH_S444046 crossref_primary_10_1002_mc_23752 crossref_primary_10_3390_ijms26062476 crossref_primary_10_1093_oncolo_oyae239 crossref_primary_10_1186_s12964_024_01549_2 crossref_primary_10_3748_wjg_v29_i37_5313 crossref_primary_10_3389_fonc_2024_1451675 crossref_primary_10_1038_s41419_024_07023_8 crossref_primary_10_3390_ijms252413586 crossref_primary_10_1016_j_ejmech_2024_116240 crossref_primary_10_46879_ukroj_2_2025_200_211 crossref_primary_10_1001_jama_2025_7515 crossref_primary_10_1002_jcb_30537 crossref_primary_10_1002_ima_70068 crossref_primary_10_3390_reports8020060 crossref_primary_10_1016_j_bmc_2024_117792 crossref_primary_10_1186_s12964_024_01745_0 crossref_primary_10_1097_MD_0000000000039408 crossref_primary_10_1016_j_bbadis_2024_167535 crossref_primary_10_3389_fonc_2023_1230519 crossref_primary_10_1371_journal_pone_0325849 crossref_primary_10_1016_j_suc_2023_11_009 crossref_primary_10_1158_1940_6207_CAPR_23_0498 crossref_primary_10_3390_ijms252312985 crossref_primary_10_3389_fonc_2024_1327400 crossref_primary_10_1002_slct_202304525 crossref_primary_10_1177_10732748251343334 crossref_primary_10_3389_fonc_2024_1343061 crossref_primary_10_3390_cancers16101820 crossref_primary_10_18663_tjcl_1667528 crossref_primary_10_1016_j_tranon_2024_101952 crossref_primary_10_1158_1078_0432_CCR_24_3275 crossref_primary_10_1136_gutjnl_2024_332891 crossref_primary_10_3390_ijms25084461 crossref_primary_10_3892_mmr_2024_13325 crossref_primary_10_1007_s00384_024_04655_2 crossref_primary_10_1016_j_gassur_2025_101990 crossref_primary_10_3390_cells12192388 crossref_primary_10_4240_wjgs_v16_i3_777 crossref_primary_10_1038_s41417_024_00739_x crossref_primary_10_1186_s12967_024_05927_9 crossref_primary_10_1080_08820139_2023_2264906 crossref_primary_10_1002_mc_23797 crossref_primary_10_1007_s12672_024_01529_5 crossref_primary_10_1016_j_bpg_2025_102014 crossref_primary_10_1016_j_ijbiomac_2024_139177 crossref_primary_10_1016_j_annonc_2024_12_006 crossref_primary_10_1038_s41598_025_07574_6 crossref_primary_10_3390_jcm12206540 crossref_primary_10_1093_jncics_pkae077 crossref_primary_10_1002_jso_27604 crossref_primary_10_1186_s13072_024_00560_8 crossref_primary_10_2147_IJN_S520616 crossref_primary_10_5812_jcrps_159313 crossref_primary_10_3390_cancers15123260 crossref_primary_10_1038_s41598_024_68147_7 crossref_primary_10_3390_cancers15245806 crossref_primary_10_1111_1475_6773_70009 crossref_primary_10_2217_bmm_2023_0591 crossref_primary_10_1016_j_cct_2024_107639 crossref_primary_10_1002_agt2_730 crossref_primary_10_2217_pgs_2023_0158 crossref_primary_10_1097_CEJ_0000000000000937 crossref_primary_10_3390_ijms25042283 crossref_primary_10_1126_sciadv_ads4985 crossref_primary_10_1111_eci_70107 crossref_primary_10_3389_fgene_2024_1349717 crossref_primary_10_1016_j_canlet_2024_217186 crossref_primary_10_3390_jcm12237267 crossref_primary_10_1245_s10434_024_15097_z crossref_primary_10_1039_D3SD00311F crossref_primary_10_3390_cancers15225359 crossref_primary_10_3390_ijerph21020213 crossref_primary_10_1080_10799893_2025_2470180 crossref_primary_10_1016_j_ccr_2025_216801 crossref_primary_10_1038_s41417_024_00842_z crossref_primary_10_7759_cureus_83806 crossref_primary_10_3390_ijms25169026 crossref_primary_10_1186_s12967_025_06334_4 crossref_primary_10_3390_ph16101448 crossref_primary_10_4236_ijcm_2025_169024 crossref_primary_10_3389_fphar_2024_1398419 crossref_primary_10_3389_fimmu_2025_1601188 crossref_primary_10_3390_ijms25158375 crossref_primary_10_7759_cureus_64277 crossref_primary_10_1515_jom_2023_0149 crossref_primary_10_1002_cbin_70050 crossref_primary_10_1148_rg_230080 crossref_primary_10_2196_73528 crossref_primary_10_1016_j_drudis_2024_104250 crossref_primary_10_1007_s13346_024_01719_2 crossref_primary_10_1016_j_phro_2025_100757 crossref_primary_10_1016_j_ejon_2024_102622 crossref_primary_10_1055_s_0044_1788912 crossref_primary_10_1080_15384047_2025_2516825 crossref_primary_10_1136_jitc_2025_011766 crossref_primary_10_3748_wjg_v30_i28_3361 crossref_primary_10_1186_s10020_024_00976_8 crossref_primary_10_3389_fphar_2024_1365949 crossref_primary_10_3390_cells13080679 crossref_primary_10_3390_ijms25126314 crossref_primary_10_3389_fendo_2024_1344058 crossref_primary_10_3390_a18050281 crossref_primary_10_1027_0227_5910_a000958 crossref_primary_10_3390_ijms25158352 crossref_primary_10_3892_ol_2024_14286 crossref_primary_10_1007_s00464_025_12079_4 crossref_primary_10_1007_s10620_024_08384_y crossref_primary_10_1158_1940_6207_CAPR_23_0443 crossref_primary_10_1007_s12029_024_01039_1 crossref_primary_10_1038_s43018_024_00878_y crossref_primary_10_1016_j_adcanc_2024_100122 crossref_primary_10_1080_14737140_2023_2236794 crossref_primary_10_1002_mco2_70137 crossref_primary_10_1186_s12967_024_05901_5 crossref_primary_10_1186_s40364_024_00640_7 crossref_primary_10_1016_j_rcro_2024_100157 crossref_primary_10_1016_j_cca_2025_120474 crossref_primary_10_1038_s41598_025_10528_7 crossref_primary_10_1200_EDBK_25_473598 crossref_primary_10_1186_s12943_025_02359_x crossref_primary_10_1186_s12967_025_06676_z crossref_primary_10_1016_j_intimp_2024_111988 crossref_primary_10_1016_j_ijpharm_2024_124838 crossref_primary_10_1016_j_jksus_2023_103041 crossref_primary_10_1002_jgh3_13064 crossref_primary_10_1186_s13287_024_03706_3 crossref_primary_10_4251_wjgo_v16_i8_3539 crossref_primary_10_1007_s00210_023_02855_1 crossref_primary_10_14309_ajg_0000000000003584 crossref_primary_10_1038_s41698_025_00989_4 crossref_primary_10_1186_s12885_025_14104_0 crossref_primary_10_1038_s41598_025_96526_1 crossref_primary_10_14309_ctg_0000000000000736 crossref_primary_10_5348_100154Z12PB2025CR crossref_primary_10_1080_02656736_2023_2290913 crossref_primary_10_1097_CEJ_0000000000000957 crossref_primary_10_1001_jama_2025_12049 crossref_primary_10_1083_jcb_202303015 crossref_primary_10_3389_fonc_2023_1341594 crossref_primary_10_3390_cancers15133447 crossref_primary_10_1002_adma_202313389 crossref_primary_10_1177_10732748241302915 crossref_primary_10_1097_MD_0000000000038145 crossref_primary_10_3390_ijms25031572 crossref_primary_10_3389_fphar_2025_1571178 crossref_primary_10_1007_s11606_024_09153_3 crossref_primary_10_7759_cureus_54467 crossref_primary_10_1038_s41392_024_02097_4 crossref_primary_10_1002_smsc_202400196 crossref_primary_10_1016_j_aca_2024_343360 crossref_primary_10_1039_D3NR06642H crossref_primary_10_3389_fimmu_2025_1642956 crossref_primary_10_1371_journal_pone_0326343 crossref_primary_10_3389_fonc_2025_1572053 crossref_primary_10_3748_wjg_v30_i16_2233 crossref_primary_10_3390_pharmaceutics15112620 crossref_primary_10_1016_j_canlet_2024_217217 crossref_primary_10_1007_s40487_023_00252_5 crossref_primary_10_3390_medicina60091536 crossref_primary_10_1021_acs_molpharmaceut_4c01144 crossref_primary_10_4274_imj_galenos_2024_64606 crossref_primary_10_1007_s12010_024_05072_5 crossref_primary_10_1016_j_heliyon_2024_e38927 crossref_primary_10_2147_JEP_S421338 crossref_primary_10_1002_cam4_70612 crossref_primary_10_1097_JS9_0000000000001854 crossref_primary_10_1016_j_cgh_2024_10_010 crossref_primary_10_1007_s12672_024_01042_9 crossref_primary_10_3389_fphar_2025_1623153 crossref_primary_10_1016_j_jss_2024_10_018 crossref_primary_10_4103_sjg_sjg_261_23 crossref_primary_10_1016_j_tranon_2024_102156 crossref_primary_10_3390_antiox13020213 crossref_primary_10_3390_cancers16081530 crossref_primary_10_1080_08830185_2024_2312294 crossref_primary_10_1177_10732748251351423 crossref_primary_10_1002_cam4_6599 crossref_primary_10_1016_j_acra_2025_01_026 crossref_primary_10_1007_s10151_024_03098_9 crossref_primary_10_3390_biomedicines13051088 crossref_primary_10_1177_15330338241250285 crossref_primary_10_3389_fpsyt_2024_1497428 crossref_primary_10_1111_ajco_14132 crossref_primary_10_3389_fgene_2024_1422827 crossref_primary_10_1016_j_clcc_2025_01_004 crossref_primary_10_1002_adhm_202401126 crossref_primary_10_1007_s12029_024_01118_3 crossref_primary_10_1016_j_gassur_2024_09_026 crossref_primary_10_1016_j_jpi_2025_100441 crossref_primary_10_3892_ijo_2023_5569 crossref_primary_10_1016_j_bcp_2025_116847 crossref_primary_10_1016_j_tranon_2024_102170 crossref_primary_10_3390_jcm12155041 crossref_primary_10_1038_s41598_025_97869_5 crossref_primary_10_3390_cancers16081553 crossref_primary_10_1038_s41417_024_00808_1 crossref_primary_10_3390_biomedicines12030518 crossref_primary_10_1016_j_actbio_2023_11_019 crossref_primary_10_1016_j_bmc_2025_118267 crossref_primary_10_1186_s12935_025_03641_0 crossref_primary_10_4240_wjgs_v17_i2_101403 crossref_primary_10_3390_diagnostics14070772 crossref_primary_10_3390_cancers17111739 crossref_primary_10_1016_j_gim_2024_101285 crossref_primary_10_1021_jacs_4c16001 crossref_primary_10_1016_j_sopen_2025_03_002 crossref_primary_10_1055_s_0044_1787883 crossref_primary_10_3389_fphar_2024_1499414 crossref_primary_10_1080_15548627_2025_2551720 crossref_primary_10_1016_j_bmcl_2025_130313 crossref_primary_10_1016_j_jconrel_2023_11_010 crossref_primary_10_2147_CMAR_S438225 crossref_primary_10_1016_j_tranon_2025_102455 crossref_primary_10_1155_2024_7139556 crossref_primary_10_1002_pbc_31830 crossref_primary_10_1007_s00261_025_05095_4 crossref_primary_10_1016_j_bbcan_2024_189198 crossref_primary_10_1186_s12876_025_03748_8 crossref_primary_10_1093_intbio_zyaf014 crossref_primary_10_2174_0109298673319340240809104237 crossref_primary_10_3322_caac_70011 crossref_primary_10_3389_fimmu_2023_1253551 crossref_primary_10_3390_cells14060455 crossref_primary_10_1186_s12885_025_14431_2 crossref_primary_10_1002_iid3_70227 crossref_primary_10_1016_j_canlet_2025_217512 crossref_primary_10_3390_toxins16050212 crossref_primary_10_3390_ijms241914641 crossref_primary_10_1007_s12029_025_01166_3 crossref_primary_10_1016_j_gie_2024_11_016 crossref_primary_10_3390_molecules28176354 crossref_primary_10_3390_scipharm93010001 crossref_primary_10_52927_jdcr_2025_13_2_112 crossref_primary_10_2196_62835 crossref_primary_10_1016_j_cgh_2024_04_029 crossref_primary_10_3390_cells14060465 crossref_primary_10_31083_j_fbl2902053 crossref_primary_10_1038_s41598_025_10574_1 crossref_primary_10_1016_j_biopha_2023_115922 crossref_primary_10_1007_s12672_025_03022_z crossref_primary_10_3389_fonc_2024_1375334 crossref_primary_10_4081_ejh_2023_3697 crossref_primary_10_1016_j_ajcnut_2025_01_005 crossref_primary_10_25122_jml_2025_0014 crossref_primary_10_3390_nu16213737 crossref_primary_10_1177_2327857925141043 crossref_primary_10_1007_s00204_024_03932_x crossref_primary_10_1186_s12967_024_04934_0 crossref_primary_10_14309_ajg_0000000000002975 crossref_primary_10_3389_fonc_2024_1394046 crossref_primary_10_1111_1751_7915_70029 crossref_primary_10_1111_jcmm_70376 crossref_primary_10_1002_jbt_23770 crossref_primary_10_1186_s12876_025_04091_8 crossref_primary_10_1038_s41598_025_99493_9 crossref_primary_10_1109_ACCESS_2024_3421296 crossref_primary_10_1177_21501319251348099 crossref_primary_10_5306_wjco_v15_i5_599 crossref_primary_10_1158_1078_0432_CCR_23_1063 crossref_primary_10_3389_fonc_2024_1363305 crossref_primary_10_1002_cncr_35369 crossref_primary_10_3389_fpubh_2025_1518536 crossref_primary_10_1177_10732748251327715 crossref_primary_10_1007_s00261_025_04861_8 crossref_primary_10_3389_fonc_2025_1496820 crossref_primary_10_3390_biomedicines13010123 crossref_primary_10_1038_s41598_025_96004_8 crossref_primary_10_1007_s10552_024_01881_5 crossref_primary_10_3390_biomedicines12091955 crossref_primary_10_1021_acsnano_5c06115 crossref_primary_10_2340_1651_226X_2025_42592 crossref_primary_10_1007_s12672_024_01691_w crossref_primary_10_1080_14737140_2023_2280643 crossref_primary_10_1186_s12876_025_03713_5 crossref_primary_10_3390_cancers16091765 crossref_primary_10_1038_s41467_025_56444_2 crossref_primary_10_1002_ptr_8258 crossref_primary_10_1159_000533429 crossref_primary_10_5888_pcd21_240020 crossref_primary_10_1007_s10900_025_01454_w crossref_primary_10_3390_ijerph22010098 crossref_primary_10_1136_egastro_2024_100106 crossref_primary_10_1371_journal_pone_0326760 crossref_primary_10_1016_j_ejso_2025_109586 crossref_primary_10_1016_j_compbiomed_2024_109136 crossref_primary_10_1177_00368504251368237 crossref_primary_10_1016_j_clon_2024_10_003 crossref_primary_10_1111_apt_17947 crossref_primary_10_1200_EDBK_431272 crossref_primary_10_1182_bloodadvances_2024013197 crossref_primary_10_1080_01635581_2024_2316934 crossref_primary_10_1186_s12885_025_13448_x crossref_primary_10_3390_ijms26051988 crossref_primary_10_4251_wjgo_v17_i7_105264 crossref_primary_10_3390_cimb46110774 crossref_primary_10_4251_wjgo_v16_i4_1248 crossref_primary_10_1016_j_jocd_2025_101597 crossref_primary_10_1038_s41416_024_02826_0 crossref_primary_10_1002_cbin_12141 crossref_primary_10_3389_fcell_2025_1543915 crossref_primary_10_1016_j_acra_2024_08_021 crossref_primary_10_3390_ijms252313001 crossref_primary_10_1016_j_phymed_2023_155290 crossref_primary_10_1038_s41420_025_02478_w crossref_primary_10_1038_s41598_025_90066_4 crossref_primary_10_3390_biomedicines11123196 crossref_primary_10_1186_s12957_024_03300_0 crossref_primary_10_3390_biomedicines12102225 crossref_primary_10_1007_s12672_025_02462_x crossref_primary_10_1007_s00432_023_05233_9 crossref_primary_10_1186_s12885_024_12122_y crossref_primary_10_1186_s12871_025_02922_5 crossref_primary_10_2174_012212697X308365240529100442 crossref_primary_10_1002_cam4_71107 crossref_primary_10_1186_s12893_025_02837_5 crossref_primary_10_3390_medicina60081365 crossref_primary_10_3390_cancers16213720 crossref_primary_10_7759_cureus_72772 crossref_primary_10_1053_j_gastro_2023_12_027 crossref_primary_10_3390_ijms241411613 crossref_primary_10_1016_j_ijbiomac_2024_134580 crossref_primary_10_3389_fphar_2025_1560714 crossref_primary_10_1016_j_yasu_2024_04_015 crossref_primary_10_1016_j_canlet_2023_216460 crossref_primary_10_1016_j_ejca_2024_114118 crossref_primary_10_1016_j_mtbio_2024_101427 crossref_primary_10_3390_healthcare12030344 crossref_primary_10_1007_s12672_023_00808_x crossref_primary_10_1002_jbt_23749 crossref_primary_10_17694_bajece_1521841 crossref_primary_10_3390_ijms241512159 crossref_primary_10_3390_antiox14040388 crossref_primary_10_3389_fmolb_2024_1385238 crossref_primary_10_1016_j_prp_2023_154964 crossref_primary_10_3389_fcell_2024_1421763 crossref_primary_10_1016_j_amjsurg_2025_116256 crossref_primary_10_1016_j_ejso_2023_07_007 crossref_primary_10_1016_j_jep_2025_119894 crossref_primary_10_1158_1078_0432_CCR_24_1934 crossref_primary_10_1038_s41576_024_00796_w crossref_primary_10_1007_s00384_025_04817_w crossref_primary_10_1016_j_yasu_2024_04_004 crossref_primary_10_3390_cells13050395 crossref_primary_10_1016_j_prp_2023_154958 crossref_primary_10_1016_j_canep_2023_102415 crossref_primary_10_1111_febs_17080 crossref_primary_10_3724_abbs_2025158 crossref_primary_10_1016_j_amjsurg_2025_116246 crossref_primary_10_3390_cancers16152622 crossref_primary_10_3724_abbs_2025154 crossref_primary_10_1136_emermed_2023_213761 crossref_primary_10_1007_s10238_024_01408_x crossref_primary_10_1007_s00595_024_02883_1 crossref_primary_10_3390_jcm12247690 crossref_primary_10_1007_s13346_025_01952_3 crossref_primary_10_1016_j_prp_2023_154945 crossref_primary_10_3390_antiox14040381 crossref_primary_10_1038_s41598_024_75746_x crossref_primary_10_1186_s13046_024_03154_0 crossref_primary_10_1158_1055_9965_EPI_24_1488 crossref_primary_10_1007_s12672_025_03071_4 crossref_primary_10_3390_ijms24098155 crossref_primary_10_1016_j_jbior_2024_101013 crossref_primary_10_1021_acsomega_4c10378 crossref_primary_10_1007_s10620_024_08762_6 crossref_primary_10_1002_cam4_70180 crossref_primary_10_7759_cureus_46575 crossref_primary_10_1016_j_molstruc_2024_138997 crossref_primary_10_3892_ol_2024_14797 crossref_primary_10_1111_imr_13273 crossref_primary_10_1007_s10238_024_01505_x crossref_primary_10_1016_j_bios_2025_117506 crossref_primary_10_1186_s12985_024_02553_1 crossref_primary_10_1093_jncics_pkaf061 crossref_primary_10_3390_cimb47020088 crossref_primary_10_3389_fphar_2024_1355644 crossref_primary_10_3390_cancers16213645 crossref_primary_10_1007_s00423_025_03692_x crossref_primary_10_1136_jitc_2024_011310 crossref_primary_10_1007_s00432_024_06007_7 crossref_primary_10_1080_14656566_2024_2435946 crossref_primary_10_3390_nu16183047 crossref_primary_10_1002_cam4_70169 crossref_primary_10_1002_mco2_576 crossref_primary_10_1053_j_gastro_2023_11_305 crossref_primary_10_1007_s12672_025_02568_2 crossref_primary_10_1093_oncolo_oyaf218 crossref_primary_10_1016_j_jare_2024_07_022 crossref_primary_10_1007_s12079_023_00791_6 crossref_primary_10_1186_s13046_024_03095_8 crossref_primary_10_3748_wjg_v30_i13_1780 crossref_primary_10_1016_j_annonc_2024_03_011 crossref_primary_10_1016_j_gastha_2025_100653 crossref_primary_10_1186_s13148_025_01844_w crossref_primary_10_3390_metabo14080463 crossref_primary_10_1145_3756012 crossref_primary_10_3390_medicina60071028 crossref_primary_10_3390_chemistry7030098 crossref_primary_10_3390_ijms25052716 crossref_primary_10_1038_s41416_024_02652_4 crossref_primary_10_20538_1682_0363_2024_4_55_63 crossref_primary_10_1016_j_nantod_2024_102594 crossref_primary_10_1177_15404153231212659 crossref_primary_10_1007_s11864_024_01191_7 crossref_primary_10_1080_87559129_2024_2446366 crossref_primary_10_1002_adtp_202400199 crossref_primary_10_1177_09636897251314645 crossref_primary_10_3390_cancers17030399 crossref_primary_10_1002_mco2_556 crossref_primary_10_1007_s00330_024_10882_6 crossref_primary_10_1055_a_2358_1479 crossref_primary_10_1016_j_heliyon_2024_e39326 crossref_primary_10_3390_biomedicines13010054 crossref_primary_10_1186_s12905_025_03828_7 crossref_primary_10_1007_s12011_024_04440_w crossref_primary_10_1186_s12957_025_03725_1 crossref_primary_10_1177_00031348251355930 crossref_primary_10_1016_j_bbrc_2023_149275 crossref_primary_10_3389_fnut_2023_1264178 crossref_primary_10_1016_j_amjsurg_2025_116191 crossref_primary_10_37349_etat_2025_1002329 crossref_primary_10_1007_s12672_025_01989_3 crossref_primary_10_1158_0008_5472_CAN_23_3486 crossref_primary_10_1093_jncics_pkaf026 crossref_primary_10_1093_jncics_pkaf027 crossref_primary_10_3390_cancers17122003 crossref_primary_10_1007_s00261_024_04656_3 crossref_primary_10_1016_j_csbj_2024_07_014 crossref_primary_10_3389_fimmu_2025_1515568 crossref_primary_10_7759_cureus_92431 crossref_primary_10_1097_MD_0000000000039300 crossref_primary_10_1186_s12885_024_12634_7 crossref_primary_10_1016_j_ejmech_2024_117036 crossref_primary_10_2147_DDDT_S454774 crossref_primary_10_1007_s10620_025_09055_2 crossref_primary_10_4103_egjp_egjp_23_24 crossref_primary_10_3390_biomedicines13040799 crossref_primary_10_1038_s41698_025_00892_y crossref_primary_10_1016_j_jbc_2025_108333 crossref_primary_10_3390_healthcare12121235 crossref_primary_10_62347_XYKG2252 crossref_primary_10_1016_j_jbo_2024_100659 crossref_primary_10_1007_s11701_025_02222_7 crossref_primary_10_3390_ph18040501 crossref_primary_10_1016_j_cclet_2023_108656 crossref_primary_10_1016_j_acra_2025_05_050 crossref_primary_10_1002_cam4_7097 crossref_primary_10_1002_ijc_35322 crossref_primary_10_3892_ol_2024_14770 crossref_primary_10_1177_10732748251321672 crossref_primary_10_1186_s13244_025_02010_9 crossref_primary_10_1016_j_clinre_2024_102301 crossref_primary_10_3389_fimmu_2024_1344637 crossref_primary_10_3389_fimmu_2024_1524560 crossref_primary_10_3390_ijms25105316 crossref_primary_10_1002_ijc_35336 crossref_primary_10_1016_j_amepre_2025_04_006 crossref_primary_10_31083_j_fbl2908276 crossref_primary_10_1016_j_clcc_2023_08_001 crossref_primary_10_1016_j_clcc_2023_08_002 crossref_primary_10_1007_s12094_024_03537_x crossref_primary_10_1111_1440_1681_13844 crossref_primary_10_1177_10815589241277829 crossref_primary_10_3390_app14177852 crossref_primary_10_3390_biom14080891 crossref_primary_10_1186_s13046_024_03114_8 crossref_primary_10_1038_s41598_024_54972_3 crossref_primary_10_3390_app14177842 crossref_primary_10_1016_j_ijrobp_2024_03_034 crossref_primary_10_1002_advs_202412953 crossref_primary_10_3164_jcbn_24_240 crossref_primary_10_3389_fonc_2025_1566681 crossref_primary_10_1007_s11912_025_01707_w crossref_primary_10_3390_jcm13041162 crossref_primary_10_1001_jamanetworkopen_2025_23271 crossref_primary_10_1016_j_bioorg_2023_107056 crossref_primary_10_1245_s10434_024_15302_z crossref_primary_10_7326_ANNALS_24_03144 crossref_primary_10_1016_j_ejon_2024_102739 crossref_primary_10_7554_eLife_97827 crossref_primary_10_13005_bpj_3001 crossref_primary_10_1038_s41598_024_83343_1 crossref_primary_10_1007_s00384_023_04508_4 crossref_primary_10_4240_wjgs_v15_i11_2470 crossref_primary_10_1038_s41586_024_07205_6 crossref_primary_10_1097_DCR_0000000000003369 crossref_primary_10_1186_s12876_024_03540_0 crossref_primary_10_3389_fmed_2024_1462870 crossref_primary_10_1016_j_tranon_2025_102368 crossref_primary_10_3390_cimb46050254 crossref_primary_10_1016_j_cclet_2023_109159 crossref_primary_10_3389_fpubh_2024_1370108 crossref_primary_10_1016_j_gendis_2025_101529 crossref_primary_10_1016_j_ejmech_2024_117062 crossref_primary_10_1016_j_cbi_2024_111218 crossref_primary_10_1007_s13346_025_01900_1 crossref_primary_10_1016_j_tranon_2025_102373 crossref_primary_10_1016_j_tranon_2025_102374 crossref_primary_10_1002_jbt_70189 crossref_primary_10_1063_5_0216291 crossref_primary_10_1186_s11658_024_00630_5 crossref_primary_10_3390_metabo13050675 crossref_primary_10_1053_j_gastro_2024_05_038 crossref_primary_10_1515_oncologie_2024_0377 crossref_primary_10_3389_fonc_2025_1509207 crossref_primary_10_1007_s10552_024_01940_x crossref_primary_10_3389_fcell_2025_1563184 crossref_primary_10_1016_j_cej_2024_155048 crossref_primary_10_7759_cureus_46525 crossref_primary_10_1002_jso_27766 crossref_primary_10_3389_fimmu_2023_1156488 crossref_primary_10_4103_JOME_JOME_33_24 crossref_primary_10_1080_03007995_2025_2475074 crossref_primary_10_3390_nu17030397 crossref_primary_10_1007_s10620_025_09122_8 crossref_primary_10_1016_j_jep_2024_117733 crossref_primary_10_3390_jcm14124339 crossref_primary_10_31083_j_fbl2905199 crossref_primary_10_1002_cncr_35727 crossref_primary_10_3389_fonc_2024_1437698 crossref_primary_10_1016_j_comptc_2023_114461 crossref_primary_10_1002_jso_27778 crossref_primary_10_1002_adma_202420586 crossref_primary_10_1093_jnci_djae052 crossref_primary_10_1093_bjsopen_zrae044 crossref_primary_10_1016_j_esmogo_2025_100170 crossref_primary_10_1016_j_tige_2024_03_006 crossref_primary_10_1016_j_tige_2024_03_003 crossref_primary_10_1016_j_tige_2024_03_001 crossref_primary_10_1007_s10552_025_01983_8 crossref_primary_10_1016_j_scrs_2025_101119 crossref_primary_10_1158_1078_0432_CCR_24_1166 crossref_primary_10_1002_cnr2_70167 crossref_primary_10_1002_adhm_202402887 crossref_primary_10_1186_s12929_024_01097_4 crossref_primary_10_1097_CEJ_0000000000000863 crossref_primary_10_3389_fmed_2025_1489842 crossref_primary_10_1007_s13577_024_01139_x crossref_primary_10_1136_gutjnl_2025_335275 crossref_primary_10_1016_j_scrs_2025_101117 crossref_primary_10_7326_ANNALS_24_00910 crossref_primary_10_1016_j_apsb_2024_09_007 crossref_primary_10_3390_molecules28248012 crossref_primary_10_2196_64506 crossref_primary_10_3390_ijms242115959 crossref_primary_10_2147_PGPM_S458798 crossref_primary_10_1097_CEJ_0000000000000834 crossref_primary_10_1002_1878_0261_13794 crossref_primary_10_1158_2767_9764_CRC_24_0633 crossref_primary_10_3389_fonc_2025_1416243 crossref_primary_10_1016_j_jcis_2025_138094 crossref_primary_10_1007_s12668_025_02003_4 crossref_primary_10_1002_cam4_6168 crossref_primary_10_1136_bmjopen_2024_086432 crossref_primary_10_1158_1078_0432_CCR_24_0281 crossref_primary_10_1016_j_saa_2024_124152 crossref_primary_10_1080_19490976_2024_2341717 crossref_primary_10_1007_s10238_024_01323_1 crossref_primary_10_1007_s13187_025_02631_0 crossref_primary_10_2147_CMAR_S482306 crossref_primary_10_1002_fft2_478 crossref_primary_10_1002_ccr3_9218 crossref_primary_10_3390_life15020156 crossref_primary_10_3748_wjg_v30_i10_1368 crossref_primary_10_1002_ags3_70084 crossref_primary_10_1177_09731296251361618 crossref_primary_10_1007_s00384_025_04853_6 crossref_primary_10_1016_j_bioelechem_2024_108897 crossref_primary_10_1016_j_acra_2024_10_004 crossref_primary_10_1007_s11377_024_00812_9 crossref_primary_10_1097_MJT_0000000000001812 crossref_primary_10_3390_metabo15060412 crossref_primary_10_3390_cancers17111782
Cites_doi	10.1200/JCO.22.01690 10.1093/jnci/djac215 10.1001/jamainternmed.2013.9294 10.3322/caac.21457 10.1158/1055‐9965.epi‐12‐0023 10.1158/1055‐9965.epi‐20‐1727 10.1158/1055‐9965.epi‐21‐0343 10.1093/jnci/djs346 10.3402/ijch.v68i2.18320 10.1136/gutjnl‐2015‐310912 10.1002/cncr.30819 10.1093/jnci/djq068 10.1056/nejmoa042990 10.3322/caac.21440 10.1056/nejmoa1100370 10.1001/jamaoncol.2020.7600 10.1093/jnci/djv229 10.1111/j.1440‐1746.2007.04923.x 10.1001/jamaoncol.2022.0883 10.1056/nejmc2112409 10.1111/j.1440‐1746.2009.05992.x 10.1093/jnci/86.13.997 10.1093/jnci/djac158 10.3747/co.19.1073 10.1200/jco.2004.00.5686 10.1001/jamaoncol.2018.4280 10.2105/ajph.2013.301654 10.1002/jso.27096 10.1093/jnci/djv210 10.1002/cncr.24760 10.1080/22423982.2021.2013403 10.1200/jco.21.02008 10.1007/s11606‐007‐0480‐1 10.3390/nu11122936 10.1001/jamaoncol.2016.4227 10.1001/jamanetworkopen.2022.15490 10.1016/s1052‐5157(03)00053‐9 10.1002/ijc.30527 10.1200/po.21.00427 10.1053/j.gastro.2014.01.013 10.3390/ijms22031354 10.1053/j.gastro.2021.02.015 10.1016/s1542‐3565(03)00294‐5 10.1158/1055‐9965.epi‐20‐1127 10.1002/cncr.34185 10.1001/jama.2021.5746 10.1038/ajg.2012.407 10.1002/cncr.27755 10.1158/1055‐9965.epi‐09‐0211 10.1016/s2468‐1253(19)30147‐5 10.1016/j.ejso.2014.11.001 10.1093/jnci/djaa164 10.1158/1055‐9965.epi‐20‐1528 10.1093/jnci/djr207 10.1016/j.clcc.2019.09.002 10.1017/s0950268815001181 10.1093/jnci/94.20.1537 10.1016/j.amepre.2009.03.009 10.1093/jnci/djac221 10.1136/gutjnl‐2019‐319511 10.1093/jnci/djx015 10.7326/m16‐1154 10.1158/1055‐9965.epi‐17‐0488 10.1056/nejm200007203430301 10.1016/j.clcc.2018.01.003 10.1093/jnci/djab200 10.1002/cncr.20288 10.1093/jnci/djv198 10.1001/jama.296.23.2815 10.1080/13696998.2021.1922240 10.1001/jama.2018.5809 10.1001/jamasurg.2014.3572 10.1093/jnci/djr310 10.1186/s12885‐018‐4786‐7 10.1002/cncr.29336 10.1002/ijc.10635 10.1016/j.soncn.2017.02.002 10.1093/jnci/djab124 10.1200/jco.21.02708 10.1016/s0140‐6736(17)30569‐x 10.1093/jnci/djw322 10.1158/1055‐9965.epi‐17‐0219 10.1002/cncr.26677 10.1002/cncr.33649 10.1056/nejmoa1301969 10.1002/cncr.32163 10.1016/j.cgh.2016.10.038 10.1016/j.jss.2015.10.021 10.1200/jco.2007.14.5631 10.1016/j.critrevonc.2016.11.005 10.1001/jama.2021.4417 10.1136/gutjnl‐2020‐323450 10.1200/jco.2008.20.5278 10.1007/s10620‐010‐1528‐3 10.1002/cncr.34390 10.6004/jnccn.2022.7056 10.1093/jnci/dju427 10.3322/caac.20121 10.1038/ncomms7342 10.3322/caac.21757 10.1002/jso.21864 10.1038/ajg.2012.161 10.1053/j.gastro.2017.11.005 10.3322/caac.21731 10.1053/j.gastro.2019.10.029 10.1097/01.mlr.0000246612.35245.21 10.1002/cncr.31994 10.1002/cncr.31543 10.1093/oxfordjournals.aje.a116143 10.1146/annurev.pu.12.050191.002233 10.1158/1055-9965.EPI-20-1780 10.1371/journal.pone.0244431 10.1158/1055‐9965.EPI‐22‐0527 10.1016/j.amjsurg.2019.09.027 10.1136/gutjnl‐2016‐312712 10.1001/jama.2021.0106 10.1016/j.jcpo.2021.100293 10.1200/jco.2017.74.2049 10.1158/1055‐9965.epi‐20‐0950 10.1136/bmj‐2021‐068921 10.1007/s40615‐015‐0174‐z 10.1007/s10552‐014‐0344‐z 10.1093/jnci/djab123 10.1053/j.gastro.2018.09.054 10.3322/canjclin.30.4.208 10.1016/j.cgh.2022.04.037
ContentType	Journal Article
Copyright	2023 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society. Copyright Wiley Subscription Services, Inc. May/Jun 2023
Copyright_xml	– notice: 2023 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society. – notice: Copyright Wiley Subscription Services, Inc. May/Jun 2023
DBID	24P AAYXX CITATION CGR CUY CVF ECM EIF NPM 7T5 7TO 7U9 8FD FR3 H94 K9. NAPCQ P64 RC3 7X8
DOI	10.3322/caac.21772
DatabaseName	Wiley Online Library Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Immunology Abstracts Oncogenes and Growth Factors Abstracts Virology and AIDS Abstracts Technology Research Database Engineering Research Database AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Genetics Abstracts Virology and AIDS Abstracts Oncogenes and Growth Factors Abstracts Technology Research Database AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Immunology Abstracts Engineering Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic
DatabaseTitleList	MEDLINE MEDLINE - Academic Nursing & Allied Health Premium CrossRef
Database_xml	– sequence: 1 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine Statistics
EISSN	1542-4863
EndPage	254
ExternalDocumentID	36856579 10_3322_caac_21772 CAAC21772
Genre	article Journal Article
GeographicLocations	United States
GeographicLocations_xml	– name: United States
GroupedDBID	.GA .GJ .Y3 0R~ 10A 18M 1CY 1OB 1OC 23N 24P 2WC 31~ 33P 4.4 41~ 50Y 50Z 51W 51X 52M 52N 52P 52R 52S 52T 52X 53G 5GY 5RE 5VS 66C 6J9 6PF 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAEVG AAHHS AAONW AAWTL AAZKR ABCQN ABEML ACBNA ACCFJ ACCMX ACGFO ACPRK ACSCC ACXQS ADBBV ADIZJ ADPDF ADXAS ADZOD AEEZP AEGXH AEIMD AEQDE AEUQT AFBPY AFFNX AFZJQ AHMBA AI. AIAGR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR ATUGU AZBYB BAFTC BAWUL BFHJK BKOMP BY8 C1A CS3 D-6 D-7 D-E D-F DCZOG DIK DR2 E3Z EBD EBS EIHBH EJD EMB EMOBN F00 F01 F04 F5P FAS FJW G-S GODZA GX1 H.X HZ~ IX1 J0M KQ8 L7B LC2 LC3 LH4 LW6 N04 N05 NF~ O66 O9- OHT OK1 OVD P2P P2W P2X P2Z P4E PQQKQ Q.N Q11 QB0 ROL RWI RWL RX1 RXW SJN SUPJJ SV3 TAE TEORI TR2 TWZ UB1 UDS VH1 W2D W8V WH7 WHWMO WIN WOHZO WOQ WQJ WRC WVDHM WXI XG1 XSB XV2 XZL YQJ ZCG ZGI ZVN ZXP ~WT AAFWJ AAYXX CITATION O8X OVT CGR CUY CVF ECM EIF NPM PKN 7T5 7TO 7U9 8FD FR3 H94 K9. NAPCQ P64 RC3 7X8
ID	FETCH-LOGICAL-c4592-2d81fec7f9764e473ee74b90575b83e44443b7d6fceea2f4d48f81e6f260cc873
IEDL.DBID	24P
ISICitedReferencesCount	2246
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000940400800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	0007-9235 1542-4863
IngestDate	Wed Oct 01 13:46:22 EDT 2025 Fri Oct 03 02:51:53 EDT 2025 Wed Feb 19 02:23:10 EST 2025 Sat Nov 29 06:53:45 EST 2025 Tue Nov 18 20:24:52 EST 2025 Wed Jan 22 16:23:12 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	3
Keywords	epidemiology health disparities screening and early detection colon and rectum neoplasms early-onset colorectal cancer
Language	English
License	Attribution-NonCommercial-NoDerivs 2023 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c4592-2d81fec7f9764e473ee74b90575b83e44443b7d6fceea2f4d48f81e6f260cc873
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ORCID	0000-0003-1337-483X 0000-0003-3344-2238 0000-0001-5247-8522
OpenAccessLink	https://onlinelibrary.wiley.com/doi/abs/10.3322%2Fcaac.21772
PMID	36856579
PQID	2811025718
PQPubID	6515
PageCount	22
ParticipantIDs	proquest_miscellaneous_2781214958 proquest_journals_2811025718 pubmed_primary_36856579 crossref_citationtrail_10_3322_caac_21772 crossref_primary_10_3322_caac_21772 wiley_primary_10_3322_caac_21772_CAAC21772
PublicationCentury	2000
PublicationDate	May/June 2023
PublicationDateYYYYMMDD	2023-05-01
PublicationDate_xml	– month: 05 year: 2023 text: May/June 2023
PublicationDecade	2020
PublicationPlace	United States
PublicationPlace_xml	– name: United States – name: Atlanta
PublicationTitle	CA: a cancer journal for clinicians
PublicationTitleAlternate	CA Cancer J Clin
PublicationYear	2023
Publisher	Wiley Subscription Services, Inc
Publisher_xml	– name: Wiley Subscription Services, Inc
References	2012; 366 1991; 12 2002; 94 2019; 11 2002; 12 2013; 369 2021; 325 2010; 102 2011; 61 2021; 160 2014; 25 2016; 144 2020; 15 2006; 296 2012; 19 2022; 20 2011; 56 2004; 2 2021; 70 2020; 19 1977 2010; 25 1980; 30 2013; 119 2010; 116 2022; 40 2008; 26 2008; 23 2019; 158 2017; 166 2020; 219 2012; 21 2019; 156 2018; 36 2009; 18 2009; 68 2019; 4 2019; 5 2005; 352 2013; 108 2015; 121 2016; 201 2012; 104 2018; 27 2012; 107 1994; 86 2022; 114 2018; 18 2023; 41 2018; 17 2016; 3 2022; 5 2022; 6 2022; 8 2017; 140 2013; 173 2000; 343 2017; 389 2012; 118 2014; 146 2012; 61 2021; 24 2017; 3 2021; 22 2022; 72 2016; 108 2021; 29 2018; 124 2021; 127 2019; 125 2015; 107 2021; 30 2005; 23 2022; 378 2021; 113 2022; 81 2000 2017; 33 2019; 68 2015; 41 2021; 39 2002; 101 2017; 123 2022; 128 2004; 101 2021; 7 2015; 6 1991; 134 2017; 26 2023; 127 2018; 67 2009; 27 2018; 68 2022; 386 2017; 109 2011; 103 2015; 150 2018; 154 2017; 15 2022 2021 2019 2018; 319 2007; 45 2012; 5 2009; 37 2014; 104 2016; 66 e_1_2_7_108_1 e_1_2_7_3_1 e_1_2_7_104_1 e_1_2_7_127_1 e_1_2_7_7_1 e_1_2_7_60_1 e_1_2_7_83_1 e_1_2_7_123_1 e_1_2_7_41_1 e_1_2_7_64_1 e_1_2_7_87_1 e_1_2_7_45_1 e_1_2_7_68_1 e_1_2_7_26_1 e_1_2_7_49_1 e_1_2_7_142_1 Creamer J (e_1_2_7_113_1) 2022 e_1_2_7_146_1 e_1_2_7_116_1 e_1_2_7_90_1 e_1_2_7_112_1 e_1_2_7_94_1 e_1_2_7_71_1 e_1_2_7_52_1 e_1_2_7_98_1 e_1_2_7_23_1 e_1_2_7_75_1 e_1_2_7_56_1 e_1_2_7_37_1 e_1_2_7_79_1 e_1_2_7_131_1 e_1_2_7_135_1 e_1_2_7_139_1 e_1_2_7_109_1 e_1_2_7_128_1 e_1_2_7_105_1 e_1_2_7_8_1 Surveillance Research Program, National Cancer Institute (e_1_2_7_17_1) 2022 e_1_2_7_124_1 e_1_2_7_101_1 e_1_2_7_16_1 Statistical Research and Applications Branch, National Cancer Institute (e_1_2_7_18_1) 2022 e_1_2_7_40_1 e_1_2_7_82_1 e_1_2_7_120_1 e_1_2_7_63_1 e_1_2_7_12_1 e_1_2_7_44_1 e_1_2_7_86_1 e_1_2_7_67_1 e_1_2_7_48_1 Kelly JJ (e_1_2_7_103_1) 2012; 5 e_1_2_7_143_1 e_1_2_7_29_1 e_1_2_7_117_1 e_1_2_7_51_1 e_1_2_7_70_1 e_1_2_7_93_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_55_1 e_1_2_7_74_1 e_1_2_7_97_1 Statistical Methodology and Applications Branch, National Cancer Institute (e_1_2_7_19_1) 2022 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_59_1 e_1_2_7_78_1 e_1_2_7_132_1 e_1_2_7_136_1 Zimpelman G (e_1_2_7_100_1) 2021 Arias E (e_1_2_7_9_1) 2021; 70 e_1_2_7_5_1 e_1_2_7_106_1 e_1_2_7_129_1 e_1_2_7_102_1 e_1_2_7_125_1 e_1_2_7_62_1 e_1_2_7_81_1 e_1_2_7_121_1 e_1_2_7_13_1 e_1_2_7_43_1 e_1_2_7_66_1 e_1_2_7_85_1 e_1_2_7_47_1 e_1_2_7_89_1 e_1_2_7_140_1 e_1_2_7_28_1 e_1_2_7_144_1 Fritz A (e_1_2_7_15_1) 2000 e_1_2_7_118_1 e_1_2_7_114_1 Centers for Disease Control and Prevention (CDC) (e_1_2_7_11_1) 2012; 61 (e_1_2_7_4_1) 2022 e_1_2_7_73_1 e_1_2_7_110_1 e_1_2_7_50_1 e_1_2_7_92_1 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_77_1 e_1_2_7_54_1 e_1_2_7_96_1 e_1_2_7_21_1 e_1_2_7_35_1 e_1_2_7_58_1 e_1_2_7_39_1 e_1_2_7_133_1 e_1_2_7_137_1 e_1_2_7_6_1 e_1_2_7_107_1 e_1_2_7_80_1 e_1_2_7_126_1 e_1_2_7_84_1 e_1_2_7_122_1 e_1_2_7_2_1 e_1_2_7_14_1 e_1_2_7_42_1 e_1_2_7_88_1 e_1_2_7_65_1 e_1_2_7_10_1 e_1_2_7_46_1 e_1_2_7_69_1 e_1_2_7_141_1 e_1_2_7_27_1 e_1_2_7_145_1 National Center for Health Statistics, Division of Health Interview Statistics (e_1_2_7_33_1) 2019 e_1_2_7_119_1 e_1_2_7_91_1 e_1_2_7_115_1 e_1_2_7_72_1 e_1_2_7_95_1 e_1_2_7_111_1 e_1_2_7_30_1 e_1_2_7_53_1 e_1_2_7_76_1 e_1_2_7_99_1 Surveillance, Epidemiology, and End Results (SEER) Program (e_1_2_7_61_1) 2022 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_57_1 e_1_2_7_130_1 e_1_2_7_38_1 e_1_2_7_134_1 e_1_2_7_138_1
References_xml	– volume: 18 start-page: 906 issue: 1 year: 2018 article-title: A review of sex‐related differences in colorectal cancer incidence, screening uptake, routes to diagnosis, cancer stage and survival in the UK publication-title: BMC Cancer – volume: 125 start-page: 2002 issue: 12 year: 2019 end-page: 2010 article-title: Clinical and molecular characterization of early‐onset colorectal cancer publication-title: Cancer – volume: 107 start-page: 1315 issue: 9 year: 2012 end-page: 1329 article-title: Serrated lesions of the colorectum: review and recommendations from an expert panel publication-title: Am J Gastroenterol – volume: 352 start-page: 2061 issue: 20 year: 2005 end-page: 2068 article-title: Colonoscopic screening of average‐risk women for colorectal neoplasia publication-title: N Engl J Med – volume: 86 start-page: 997 issue: 13 year: 1994 end-page: 1006 article-title: Temporal patterns in colorectal cancer incidence, survival, and mortality from 1950 through 1990 publication-title: J Natl Cancer Inst – volume: 123 start-page: 4022 issue: 20 year: 2017 end-page: 4030 article-title: Adolescent body mass index and risk of colon and rectal cancer in a cohort of 1.79 million Israeli men and women: a population‐based study publication-title: Cancer – volume: 4 start-page: 511 issue: 7 year: 2019 end-page: 518 article-title: Changes in colorectal cancer incidence in seven high‐income countries: a population‐based study publication-title: Lancet Gastroenterol Hepatol – volume: 127 start-page: 3801 issue: 20 year: 2021 end-page: 3808 article-title: Racial differences in survival and response to therapy in patients with metastatic colorectal cancer: a secondary analysis of CALGB/SWOG 80405 (Alliance A151931) publication-title: Cancer – volume: 146 start-page: 950 issue: 4 year: 2014 end-page: 960 article-title: Characteristics of missed or interval colorectal cancer and patient survival: a population‐based study publication-title: Gastroenterology – volume: 134 start-page: 675 issue: 7 year: 1991 end-page: 688 article-title: Progress against cancer: an epidemiologic assessment. The 1991 John C. Cassel Memorial Lecture publication-title: Am J Epidemiol – volume: 20 start-page: 1169 issue: 10 year: 2022 end-page: 1175 article-title: Diagnosis and management of rectal cancer in patients younger than 50 years: rising global incidence and unique challenges publication-title: J Natl Compr Cancer Netw – volume: 107 issue: 10 year: 2015 article-title: Patterns of colorectal cancer care in the United States: 1990‐2010 publication-title: J Natl Cancer Inst – volume: 81 issue: 1 year: 2022 article-title: The Alaska Native Tumour Registry: fifty years of cancer surveillance data for Alaska Native people publication-title: Int J Circumpolar Health – volume: 30 start-page: 1620 issue: 9 year: 2021 end-page: 1626 article-title: Updated methodology for projecting U.S.‐ and state‐level cancer counts for the current calendar year: part I: spatio‐temporal modeling for cancer incidence publication-title: Cancer Epidemiol Biomarkers Prev – volume: 29 year: 2021 article-title: Characteristics of colorectal cancers among Alaska Native people before and after implementing programs to promote screening publication-title: J Cancer Policy – publication-title: J Natl Cancer Inst – volume: 113 start-page: 1693 issue: 12 year: 2021 end-page: 1704 article-title: Clinicopathological and molecular characteristics of early‐onset stage III colon adenocarcinoma: an analysis of the ACCENT database publication-title: J Natl Cancer Inst – volume: 128 start-page: 2236 issue: 12 year: 2022 end-page: 2239 article-title: Top advances of the year in colorectal cancer publication-title: Cancer – volume: 19 start-page: e49 issue: 2 year: 2020 end-page: e57 article-title: Outcomes among minority patients with metastatic colorectal cancer in a safety‐net health care system publication-title: Clin Colorectal Cancer – volume: 68 start-page: 31 issue: 1 year: 2018 end-page: 54 article-title: Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States publication-title: CA Cancer J Clin – volume: 108 start-page: 208 issue: 2 year: 2013 end-page: 215 article-title: Helicobacter pylori is a risk factor for colonic neoplasms publication-title: Am J Gastroenterol – volume: 3 start-page: 555 issue: 4 year: 2016 end-page: 564 article-title: Toward the elimination of colorectal cancer disparities among African Americans publication-title: J Racial Ethn Health Disparities – volume: 27 start-page: 3677 issue: 22 year: 2009 end-page: 3683 article-title: Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy publication-title: J Clin Oncol – volume: 19 start-page: e404 issue: 6 year: 2012 end-page: e413 article-title: Disparities in timeliness of care for U.S. Medicare patients diagnosed with cancer publication-title: Curr Oncol – volume: 12 start-page: 425 issue: 1 year: 1991 end-page: 457 article-title: Understanding the effects of age, period, and cohort on incidence and mortality rates publication-title: Annu Rev Public Health – volume: 8 start-page: 986 issue: 7 year: 2022 end-page: 993 article-title: Age at initiation of lower gastrointestinal endoscopy and colorectal cancer risk among US women publication-title: JAMA Oncol – volume: 33 start-page: 121 issue: 2 year: 2017 end-page: 128 article-title: Cancer screening and early detection in the 21(st) century publication-title: Semin Oncol Nurs – year: 2022 – volume: 37 start-page: 1 issue: 1 year: 2009 end-page: 7 article-title: Trends in colorectal cancer test use in the Medicare population, 1998‐2005 publication-title: Am J Prev Med – volume: 101 start-page: 403 issue: 5 year: 2002 end-page: 408 article-title: Are there two sides to colorectal cancer? publication-title: Int J Cancer – volume: 158 start-page: 354 issue: 2 year: 2019 end-page: 367 article-title: Causes of socioeconomic disparities in colorectal cancer and intervention framework and strategies publication-title: Gastroenterology – volume: 36 start-page: 25 issue: 1 year: 2018 end-page: 33 article-title: Racial and ethnic disparities in cancer survival: the contribution of tumor, sociodemographic, institutional, and neighborhood characteristics publication-title: J Clin Oncol – volume: 160 start-page: 2018 issue: 6 year: 2021 end-page: 2028.e13 article-title: Colorectal cancer incidence after colonoscopy at ages 45‐49 or 50‐54 years publication-title: Gastroenterology – year: 2022 article-title: Cancer statistics for American Indian and Alaska Native individuals, 2022: including increasing disparities in early onset colorectal cancer publication-title: CA Cancer J Clin – volume: 30 start-page: 208 issue: 4 year: 1980 end-page: 215 article-title: Cancer of the colon and rectum publication-title: CA Cancer J Clin – volume: 108 start-page: 154 year: 2016 end-page: 163 article-title: Treatments for colorectal liver metastases: a new focus on a familiar concept publication-title: Crit Rev Oncol Hematol – volume: 25 start-page: 419 issue: 4 year: 2014 end-page: 423 article-title: Disparities in survival improvement for metastatic colorectal cancer by race/ethnicity and age in the United States publication-title: Cancer Causes Control – volume: 103 start-page: 796 issue: 8 year: 2011 end-page: 800 article-title: Predictors of cure after hepatic resection of colorectal liver metastases: an analysis of actual 5‐ and 10‐year survivors publication-title: J Surg Oncol – volume: 113 start-page: 1683 issue: 12 year: 2021 end-page: 1692 article-title: A comprehensive comparison of early‐onset and average‐onset colorectal cancers publication-title: J Natl Cancer Inst – volume: 7 start-page: 458 issue: 3 year: 2021 end-page: 460 article-title: Cancer screening tests and cancer diagnoses during the COVID‐19 pandemic publication-title: JAMA Oncol – year: 2019 – volume: 144 start-page: 225 issue: 2 year: 2016 end-page: 233 article-title: The diagnosis and treatment of Helicobacter pylori infection in Arctic regions with a high prevalence of infection: expert commentary publication-title: Epidemiol Infect – volume: 18 start-page: 2310 issue: 8 year: 2009 end-page: 2317 article-title: The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectum publication-title: Cancer Epidemiol Biomarkers Prev – volume: 72 start-page: 409 issue: 5 year: 2022 end-page: 436 article-title: Cancer treatment and survivorship statistics, 2022 publication-title: CA Cancer J Clin – volume: 5 start-page: 149 issue: 5 year: 2012 end-page: 154 article-title: Colorectal cancer in Alaska Native people, 2005‐2009 publication-title: Gastrointest Cancer Res – volume: 366 start-page: 687 issue: 8 year: 2012 end-page: 696 article-title: Colonoscopic polypectomy and long‐term prevention of colorectal‐cancer deaths publication-title: N Engl J Med – volume: 2 start-page: 72 issue: 1 year: 2004 end-page: 77 article-title: Colonoscopy practice patterns since introduction of Medicare coverage for average‐risk screening publication-title: Clin Gastroenterol Hepatol – volume: 104 start-page: 1353 issue: 18 year: 2012 end-page: 1362 article-title: Contribution of behavioral risk factors and obesity to socioeconomic differences in colorectal cancer incidence publication-title: J Natl Cancer Inst – volume: 17 start-page: e281 issue: 2 year: 2018 end-page: e288 article-title: Hormone replacement therapy and colorectal cancer incidence and mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial publication-title: Clin Colorectal Cancer – volume: 102 start-page: 538 issue: 8 year: 2010 end-page: 546 article-title: Race and colorectal cancer disparities: health‐care utilization vs. different cancer susceptibilities publication-title: J Natl Cancer Inst – volume: 41 start-page: 678 issue: 3 year: 2023 end-page: 700 article-title: Treatment of metastatic colorectal cancer: ASCO guideline publication-title: J Clin Oncol – volume: 30 start-page: 1792 issue: 10 year: 2021 end-page: 1798 article-title: Metabolic risk factors associated with early‐onset colorectal adenocarcinoma: a case‐control study at Kaiser Permanente Southern California publication-title: Cancer Epidemiol Biomarkers Prev – volume: 114 start-page: 1476 issue: 11 year: 2022 end-page: 1483 article-title: Estimation of the number of individuals living with metastatic cancer in the United States publication-title: J Natl Cancer Inst – volume: 114 start-page: 427 issue: 3 year: 2022 end-page: 435 article-title: Survival in young‐onset metastatic colorectal cancer: findings from Cancer and Leukemia Group B (Alliance)/SWOG 80405 publication-title: J Natl Cancer Inst – volume: 156 start-page: 175 issue: 1 year: 2019 end-page: 186.e2 article-title: Serologic response to Helicobacter pylori proteins associated with risk of colorectal cancer among diverse populations in the United States publication-title: Gastroenterology – volume: 118 start-page: 3636 issue: 14 year: 2012 end-page: 3644 article-title: Socioeconomic status and the risk of colorectal cancer: an analysis of more than a half million adults in the National Institutes of Health‐AARP Diet and Health Study publication-title: Cancer – volume: 21 start-page: 728 issue: 5 year: 2012 end-page: 736 article-title: Contribution of screening and survival differences to racial disparities in colorectal cancer rates publication-title: Cancer Epidemiol Biomarkers Prev – volume: 61 start-page: 212 issue: 4 year: 2011 end-page: 236 article-title: Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths publication-title: CA Cancer J Clin – volume: 5 start-page: 37 issue: 1 year: 2019 end-page: 44 article-title: Association of obesity with risk of early‐onset colorectal cancer among women publication-title: JAMA Oncol – volume: 319 start-page: 2021 issue: 19 year: 2018 end-page: 2031 article-title: Association of colonoscopy adenoma findings with long‐term colorectal cancer incidence publication-title: JAMA – volume: 6 year: 2022 article-title: Disparities in biomarker testing and clinical trial enrollment among patients with lung, breast, or colorectal cancers in the United States publication-title: JCO Precis Oncol – volume: 107 issue: 3 year: 2015 article-title: Primary tumor location as a prognostic factor in metastatic colorectal cancer publication-title: J Natl Cancer Inst – publication-title: Cancer Epidemiol Biomarkers Prev – volume: 24 start-page: 654 issue: 1 year: 2021 end-page: 664 article-title: Real‐world cost‐effectiveness of stool‐based colorectal cancer screening in a Medicare population publication-title: J Med Econ – volume: 343 start-page: 162 issue: 3 year: 2000 end-page: 168 article-title: Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380 publication-title: N Engl J Med – volume: 109 issue: 9 year: 2017 article-title: Local treatment of unresectable colorectal liver metastases: results of a randomized phase II trial publication-title: J Natl Cancer Inst – volume: 325 start-page: 1998 issue: 19 year: 2021 end-page: 2011 article-title: Colorectal cancer screening: an updated odelling study for the US Preventive Services Task Force publication-title: JAMA – volume: 113 start-page: 543 issue: 5 year: 2021 end-page: 552 article-title: Comprehensive assessment of diet quality and risk of precursors of early‐onset colorectal cancer publication-title: J Natl Cancer Inst – volume: 68 start-page: 250 issue: 4 year: 2018 end-page: 281 article-title: Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society publication-title: CA Cancer J Clin – volume: 116 start-page: 544 issue: 3 year: 2010 end-page: 573 article-title: Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates publication-title: Cancer – volume: 23 start-page: 418 issue: 3 year: 2008 end-page: 423 article-title: Differences between right‐ and left‐sided colon cancer in patient characteristics, cancer morphology and histology publication-title: J Gastroenterol Hepatol – volume: 201 start-page: 196 issue: 1 year: 2016 end-page: 201 article-title: Conditional survival in advanced colorectal cancer and surgery publication-title: J Surg Res – volume: 11 issue: 12 year: 2019 article-title: Dietary factors in the control of gut homeostasis, intestinal stem cells, and colorectal cancer publication-title: Nutrients – volume: 107 issue: 10 year: 2015 article-title: A prospective evaluation of endogenous sex hormone levels and colorectal cancer risk in postmenopausal women publication-title: J Natl Cancer Inst – volume: 45 start-page: 160 issue: 2 year: 2007 end-page: 167 article-title: Trends in colonoscopy for colorectal cancer screening publication-title: Med Care – volume: 68 start-page: 109 issue: 2 year: 2009 end-page: 122 article-title: Dietary intake of Alaska Native people in two regions and implications for health: the Alaska Native Dietary and Subsistence Food Assessment Project publication-title: Int J Circumpolar Health – volume: 109 issue: 8 year: 2017 article-title: Colorectal cancer incidence patterns in the United States, 1974‐2013 publication-title: J Natl Cancer Inst – year: 2021 – volume: 30 start-page: 1993 issue: 11 year: 2021 end-page: 2000 article-title: Updated methodology for projecting U.S.‐ and state‐level cancer counts for the current calendar year: part II: evaluation of incidence and mortality projection methods publication-title: Cancer Epidemiol Biomarkers Prev – volume: 15 issue: 12 year: 2020 article-title: Estimating the impact of differential adherence on the comparative effectiveness of stool‐based colorectal cancer screening using the CRC‐AIM microsimulation model publication-title: PLoS One – volume: 70 start-page: 1 issue: 12 year: 2021 end-page: 27 article-title: Mortality profile of the non‐Hispanic American Indian or Alaska Native population, 2019 publication-title: Natl Vital Stat Rep – volume: 386 start-page: 796 issue: 8 year: 2022 end-page: 798 article-title: Association between improved colorectal screening and racial disparities publication-title: N Engl J Med – volume: 104 start-page: S404 issue: suppl 3 year: 2014 end-page: S414 article-title: Geographic variation in colorectal cancer incidence and mortality, age of onset, and stage at diagnosis among American Indian and Alaska Native people, 1990‐2009 publication-title: Am J Public Health – volume: 325 start-page: 669 issue: 7 year: 2021 end-page: 685 article-title: Diagnosis and treatment of metastatic colorectal cancer: a review publication-title: JAMA – volume: 20 start-page: 2895 issue: 12 year: 2022 end-page: 2904.e94 article-title: Adenoma and sessile serrated lesion detection rates at screening colonoscopy for ages 45‐49 years vs. older ages since the introduction of new colorectal cancer screening guidelines publication-title: Clin Gastroenterol Hepatol – volume: 15 start-page: 728 issue: 5 year: 2017 end-page: 737.e3 article-title: Advanced‐stage colorectal cancer in persons younger than 50 years not associated with longer duration of symptoms or time to diagnosis publication-title: Clin Gastroenterol Hepatol – volume: 12 start-page: 1 issue: 1 year: 2002 end-page: 9 article-title: The advanced adenoma as the primary target of screening publication-title: Gastrointest Endosc Clin N Am – volume: 296 start-page: 2815 issue: 23 year: 2006 end-page: 2822 article-title: Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer publication-title: JAMA – volume: 66 start-page: 683 issue: 4 year: 2016 end-page: 691 article-title: Global patterns and trends in colorectal cancer incidence and mortality publication-title: Gut – volume: 173 start-page: 1725 issue: 18 year: 2013 end-page: 1732 article-title: Comparative effectiveness of fecal immunochemical test outreach, colonoscopy outreach, and usual care for boosting colorectal cancer screening among the underserved: a randomized clinical trial publication-title: JAMA Intern Med – volume: 3 start-page: 211 issue: 2 year: 2017 end-page: 219 article-title: Prognostic survival associated with left‐sided vs. right‐sided colon cancer: a systematic review and meta‐analysis publication-title: JAMA Oncol – volume: 25 start-page: 33 issue: 1 year: 2010 end-page: 42 article-title: Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer publication-title: J Gastroenterol Hepatol – volume: 389 start-page: 1453 issue: 10077 year: 2017 end-page: 1463 article-title: Structural racism and health inequities in the USA: evidence and interventions publication-title: Lancet – volume: 94 start-page: 1537 issue: 20 year: 2002 end-page: 1545 article-title: Impact of reporting delay and reporting error on cancer incidence rates and trends publication-title: J Natl Cancer Inst – volume: 30 start-page: 1387 issue: 7 year: 2021 end-page: 1396 article-title: Cancer mortality disparities among Asian American and Native Hawaiian/Pacific Islander populations in California publication-title: Cancer Epidemiol Biomarkers Prev – volume: 150 start-page: 402 issue: 5 year: 2015 end-page: 409 article-title: Overtreatment of young adults with colon cancer: more intense treatments with unmatched survival gains publication-title: JAMA Surg – year: 2022 article-title: Body mass index and molecular subtypes of colorectal cancer publication-title: J Natl Cancer Inst – volume: 30 start-page: 529 issue: 3 year: 2021 end-page: 538 article-title: Understanding racial disparities in gastrointestinal cancer outcomes: lack of surgery contributes to lower survival in African American patients publication-title: Cancer Epidemiol Biomarkers Prev – volume: 23 start-page: 8671 issue: 34 year: 2005 end-page: 8678 article-title: Phase III study of fluorouracil, leucovorin, and levamisole in high‐risk stage II and III colon cancer: final report of Intergroup 0089 publication-title: J Clin Oncol – volume: 39 start-page: 4009 issue: 36 year: 2021 end-page: 4019 article-title: Early‐onset colorectal adenocarcinoma in the IDEA database: treatment adherence, toxicities, and outcomes with 3 and 6 months of adjuvant fluoropyrimidine and oxaliplatin publication-title: J Clin Oncol – volume: 127 start-page: 109 issue: 1 year: 2023 end-page: 118 article-title: Race, age, and sex differences on the influence of obesity on colorectal cancer sidedness and mortality: a national cross‐sectional study publication-title: J Surg Oncol – volume: 26 start-page: 1192 issue: 8 year: 2017 end-page: 1208 article-title: Updated review of prevalence of major risk factors and use of screening tests for cancer in the United States publication-title: Cancer Epidemiol Biomarkers Prev – volume: 70 start-page: 2330 issue: 12 year: 2021 end-page: 2336 article-title: Sugar‐sweetened beverage intake in adulthood and adolescence and risk of early‐onset colorectal cancer among women publication-title: Gut – volume: 103 start-page: 1130 issue: 14 year: 2011 end-page: 1133 article-title: Effect of misclassified underlying cause of death on survival estimates of colon and rectal cancer publication-title: J Natl Cancer Inst – volume: 369 start-page: 1095 issue: 12 year: 2013 end-page: 1105 article-title: Long‐term colorectal‐cancer incidence and mortality after lower endoscopy publication-title: N Engl J Med – volume: 128 start-page: 3531 issue: 19 year: 2022 end-page: 3540 article-title: Sex disparities in the incidence of 21 cancer types: quantification of the contribution of risk factors publication-title: Cancer – volume: 26 start-page: 2155 issue: 13 year: 2008 end-page: 2161 article-title: Impact of positron emission tomography/computed tomography and positron emission tomography (PET) alone on expected management of patients with cancer: initial results from the National Oncologic PET Registry publication-title: J Clin Oncol – volume: 23 start-page: 169 issue: 2 year: 2008 end-page: 174 article-title: Community‐based preferences for stool cards versus colonoscopy in colorectal cancer screening publication-title: J Gen Intern Med – volume: 41 start-page: 300 issue: 3 year: 2015 end-page: 308 article-title: Is right‐sided colon cancer different to left‐sided colorectal cancer?—a systematic review publication-title: Eur J Surg Oncol – volume: 107 issue: 10 year: 2015 article-title: Racial disparities in colorectal cancer survival: is elimination of variation in care the cure? publication-title: J Natl Cancer Inst – volume: 27 start-page: 245 issue: 3 year: 2018 end-page: 253 article-title: Multilevel small‐area estimation of colorectal cancer screening in the United States publication-title: Cancer Epidemiol Biomarkers Prev – year: 2000 – volume: 125 start-page: 4139 issue: 23 year: 2019 end-page: 4147 article-title: Targeted therapy for colorectal cancer metastases: a review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer publication-title: Cancer – volume: 119 start-page: 395 issue: 2 year: 2013 end-page: 403 article-title: Adjuvant chemotherapy for stage III colon cancer in the oldest old: results beyond clinical guidelines publication-title: Cancer – year: 1977 – volume: 6 issue: 1 year: 2015 article-title: Fat, fibre and cancer risk in African Americans and rural Africans publication-title: Nat Commun – volume: 325 start-page: 1978 issue: 19 year: 2021 end-page: 1998 article-title: Screening for colorectal cancer: updated evidence report and systematic review for the US Preventive Services Task Force publication-title: JAMA – volume: 68 start-page: 2179 issue: 12 year: 2019 end-page: 2185 article-title: Global patterns and trends in colorectal cancer incidence in young adults publication-title: Gut – volume: 378 year: 2022 article-title: Association of ultra‐processed food consumption with colorectal cancer risk among men and women: results from three prospective US cohort studies publication-title: BMJ – volume: 121 start-page: 2281 issue: 13 year: 2015 end-page: 2285 article-title: Public health impact of achieving 80% colorectal cancer screening rates in the United States by 2018 publication-title: Cancer – volume: 67 start-page: 291 issue: 2 year: 2018 end-page: 298 article-title: Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community‐based study publication-title: Gut – volume: 30 start-page: 1799 issue: 10 year: 2021 end-page: 1806 article-title: Growing disparity in the incidence of colorectal cancer among non‐Hispanic American Indian and Alaska Native populations—United States, 2013‐2017 publication-title: Cancer Epidemiol Biomarkers Prev – volume: 154 start-page: 906 issue: 4 year: 2018 end-page: 915.e7 article-title: Factors that contribute to differences in survival of black vs. white patients with colorectal cancer publication-title: Gastroenterology – volume: 5 issue: 6 year: 2022 article-title: Changes in cancer screening in the US during the COVID‐19 pandemic publication-title: JAMA Netw Open – volume: 56 start-page: 2104 issue: 7 year: 2011 end-page: 2113 article-title: Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan Natives in the Indian Health Service publication-title: Dig Dis Sci – volume: 101 start-page: 3 issue: 1 year: 2004 end-page: 27 article-title: Annual report to the nation on the status of cancer, 1975‐2001, with a special feature regarding survival publication-title: Cancer – volume: 140 start-page: 1082 issue: 5 year: 2017 end-page: 1090 article-title: Heterogeneity of colorectal cancer risk by tumour characteristics: large prospective study of UK women publication-title: Int J Cancer – volume: 22 issue: 3 year: 2021 article-title: The Importance of sex in the discovery of colorectal cancer prognostic biomarkers publication-title: Int J Mol Sci – volume: 166 start-page: 857 issue: 12 year: 2017 end-page: 866 article-title: Racial and ethnic disparities in interval colorectal cancer incidence: a population‐based cohort study publication-title: Ann Intern Med – volume: 219 start-page: 988 issue: 6 year: 2020 end-page: 992 article-title: Disparities in colorectal cancer mortality for rural populations in the United States: does screening matter? publication-title: Am J Surg – volume: 61 start-page: 410 issue: 22 year: 2012 end-page: 413 article-title: Methodologic changes in the Behavioral Risk Factor Surveillance System in 2011 and potential effects on prevalence estimates publication-title: MMWR Morb Mortal Wkly Rep – volume: 103 start-page: 1498 issue: 20 year: 2011 end-page: 1506 article-title: Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: an analysis of ACCENT adjuvant trials publication-title: J Natl Cancer Inst – volume: 124 start-page: 2964 issue: 14 year: 2018 end-page: 2973 article-title: The impact of the rising colorectal cancer incidence in young adults on the optimal age to start screening: microsimulation analysis I to inform the American Cancer Society colorectal cancer screening guideline publication-title: Cancer – volume: 40 start-page: 2662 issue: 24 year: 2022 end-page: 2680 article-title: Practical considerations in diagnosing and managing early‐onset GI cancers publication-title: J Clin Oncol – ident: e_1_2_7_82_1 doi: 10.1200/JCO.22.01690 – ident: e_1_2_7_52_1 doi: 10.1093/jnci/djac215 – ident: e_1_2_7_139_1 doi: 10.1001/jamainternmed.2013.9294 – ident: e_1_2_7_20_1 doi: 10.3322/caac.21457 – ident: e_1_2_7_116_1 doi: 10.1158/1055‐9965.epi‐12‐0023 – ident: e_1_2_7_130_1 – ident: e_1_2_7_13_1 doi: 10.1158/1055‐9965.epi‐20‐1727 – ident: e_1_2_7_97_1 doi: 10.1158/1055‐9965.epi‐21‐0343 – volume-title: Surveillance, Epidemiology, and End Results (SEER) Program. SEERStat Database: North American Association of Central Cancer Registries (NAACCR) Incidence Data‐Cancer in North America Research Data, 1995‐2019, with Race/Ethnicity, Standard File, American Cancer Society Facts & Figures Projection Project (which includes data from the Centers for Disease Control and Prevention’s National Program of Cancer Registries, the Canadian Counsel of Cancer Registry’s Provincial and Territorial Registries, and the National Cancer Institute’s SEER Registries), certified by the NAACCR as meeting high‐quality data standards for the specified time periods, submitted December 2021 year: 2022 ident: e_1_2_7_4_1 – ident: e_1_2_7_115_1 doi: 10.1093/jnci/djs346 – ident: e_1_2_7_102_1 doi: 10.3402/ijch.v68i2.18320 – ident: e_1_2_7_126_1 doi: 10.1136/gutjnl‐2015‐310912 – ident: e_1_2_7_51_1 doi: 10.1002/cncr.30819 – ident: e_1_2_7_119_1 doi: 10.1093/jnci/djq068 – ident: e_1_2_7_27_1 doi: 10.1056/nejmoa042990 – ident: e_1_2_7_2_1 doi: 10.3322/caac.21440 – ident: e_1_2_7_129_1 doi: 10.1056/nejmoa1100370 – ident: e_1_2_7_137_1 doi: 10.1001/jamaoncol.2020.7600 – ident: e_1_2_7_89_1 doi: 10.1093/jnci/djv229 – volume-title: DevCan: Probability of Developing or Dying of Cancer Software, version 6.8.0 year: 2022 ident: e_1_2_7_19_1 – ident: e_1_2_7_24_1 doi: 10.1111/j.1440‐1746.2007.04923.x – ident: e_1_2_7_135_1 doi: 10.1001/jamaoncol.2022.0883 – ident: e_1_2_7_8_1 – ident: e_1_2_7_90_1 doi: 10.1056/nejmc2112409 – ident: e_1_2_7_93_1 doi: 10.1111/j.1440‐1746.2009.05992.x – ident: e_1_2_7_10_1 – ident: e_1_2_7_34_1 doi: 10.1093/jnci/86.13.997 – ident: e_1_2_7_73_1 doi: 10.1093/jnci/djac158 – ident: e_1_2_7_86_1 doi: 10.3747/co.19.1073 – ident: e_1_2_7_88_1 doi: 10.1200/jco.2004.00.5686 – ident: e_1_2_7_49_1 doi: 10.1001/jamaoncol.2018.4280 – ident: e_1_2_7_104_1 doi: 10.2105/ajph.2013.301654 – ident: e_1_2_7_125_1 doi: 10.1002/jso.27096 – ident: e_1_2_7_94_1 doi: 10.1093/jnci/djv210 – ident: e_1_2_7_29_1 doi: 10.1002/cncr.24760 – ident: e_1_2_7_101_1 doi: 10.1080/22423982.2021.2013403 – ident: e_1_2_7_65_1 doi: 10.1200/jco.21.02008 – ident: e_1_2_7_140_1 doi: 10.1007/s11606‐007‐0480‐1 – ident: e_1_2_7_54_1 doi: 10.3390/nu11122936 – ident: e_1_2_7_92_1 doi: 10.1001/jamaoncol.2016.4227 – ident: e_1_2_7_138_1 doi: 10.1001/jamanetworkopen.2022.15490 – volume: 61 start-page: 410 issue: 22 year: 2012 ident: e_1_2_7_11_1 article-title: Methodologic changes in the Behavioral Risk Factor Surveillance System in 2011 and potential effects on prevalence estimates publication-title: MMWR Morb Mortal Wkly Rep – ident: e_1_2_7_3_1 doi: 10.1016/s1052‐5157(03)00053‐9 – ident: e_1_2_7_26_1 doi: 10.1002/ijc.30527 – volume-title: International Classification of Diseases for Oncology. 3rd ed year: 2000 ident: e_1_2_7_15_1 – ident: e_1_2_7_84_1 doi: 10.1200/po.21.00427 – ident: e_1_2_7_145_1 doi: 10.1053/j.gastro.2014.01.013 – ident: e_1_2_7_96_1 doi: 10.3390/ijms22031354 – ident: e_1_2_7_136_1 doi: 10.1053/j.gastro.2021.02.015 – ident: e_1_2_7_30_1 doi: 10.1016/s1542‐3565(03)00294‐5 – ident: e_1_2_7_50_1 doi: 10.1158/1055‐9965.epi‐20‐1127 – ident: e_1_2_7_80_1 doi: 10.1002/cncr.34185 – volume-title: Poverty in the United States: 2021. Current Population Reports. Report No. P60‐277 year: 2022 ident: e_1_2_7_113_1 – ident: e_1_2_7_132_1 doi: 10.1001/jama.2021.5746 – ident: e_1_2_7_106_1 doi: 10.1038/ajg.2012.407 – ident: e_1_2_7_62_1 doi: 10.1002/cncr.27755 – ident: e_1_2_7_121_1 doi: 10.1158/1055‐9965.epi‐09‐0211 – ident: e_1_2_7_47_1 doi: 10.1016/s2468‐1253(19)30147‐5 – ident: e_1_2_7_25_1 doi: 10.1016/j.ejso.2014.11.001 – ident: e_1_2_7_56_1 doi: 10.1093/jnci/djaa164 – ident: e_1_2_7_98_1 doi: 10.1158/1055‐9965.epi‐20‐1528 – ident: e_1_2_7_16_1 doi: 10.1093/jnci/djr207 – ident: e_1_2_7_85_1 doi: 10.1016/j.clcc.2019.09.002 – ident: e_1_2_7_105_1 doi: 10.1017/s0950268815001181 – ident: e_1_2_7_6_1 – ident: e_1_2_7_5_1 doi: 10.1093/jnci/94.20.1537 – ident: e_1_2_7_32_1 doi: 10.1016/j.amepre.2009.03.009 – ident: e_1_2_7_58_1 doi: 10.1093/jnci/djac221 – ident: e_1_2_7_48_1 doi: 10.1136/gutjnl‐2019‐319511 – volume-title: Joinpoint Regression Program, version 4.9.1.0 year: 2022 ident: e_1_2_7_18_1 – ident: e_1_2_7_77_1 doi: 10.1093/jnci/djx015 – ident: e_1_2_7_118_1 doi: 10.7326/m16‐1154 – ident: e_1_2_7_110_1 doi: 10.1158/1055‐9965.epi‐17‐0488 – ident: e_1_2_7_39_1 doi: 10.1056/nejm200007203430301 – ident: e_1_2_7_95_1 doi: 10.1016/j.clcc.2018.01.003 – ident: e_1_2_7_69_1 doi: 10.1093/jnci/djab200 – ident: e_1_2_7_128_1 doi: 10.1002/cncr.20288 – ident: e_1_2_7_63_1 doi: 10.1093/jnci/djv198 – ident: e_1_2_7_70_1 doi: 10.1001/jama.296.23.2815 – ident: e_1_2_7_146_1 doi: 10.1080/13696998.2021.1922240 – ident: e_1_2_7_38_1 doi: 10.1001/jama.2018.5809 – ident: e_1_2_7_64_1 doi: 10.1001/jamasurg.2014.3572 – ident: e_1_2_7_87_1 doi: 10.1093/jnci/djr310 – ident: e_1_2_7_22_1 doi: 10.1186/s12885‐018‐4786‐7 – volume-title: SEERStat Database: North American Association of Central Cancer Registries (NAACCR) Incidence Data‐Cancer in North America (CiNA) Research Data, 1998‐2019, delay‐adjusted factors—American Cancer Society Facts & Figures (which includes data from the Centers for Disease and Control and Prevention’s National Program of Cancer Registries and the National Cancer Institute’s SEER Registries), certified by the NAACCR as meeting high‐quality data standards, submitted December 2021 year: 2022 ident: e_1_2_7_61_1 – ident: e_1_2_7_141_1 doi: 10.1002/cncr.29336 – ident: e_1_2_7_23_1 doi: 10.1002/ijc.10635 – ident: e_1_2_7_40_1 doi: 10.1016/j.soncn.2017.02.002 – ident: e_1_2_7_60_1 doi: 10.1093/jnci/djab124 – ident: e_1_2_7_66_1 doi: 10.1200/jco.21.02708 – ident: e_1_2_7_112_1 doi: 10.1016/s0140‐6736(17)30569‐x – ident: e_1_2_7_45_1 doi: 10.1093/jnci/djw322 – ident: e_1_2_7_37_1 doi: 10.1158/1055‐9965.epi‐17‐0219 – ident: e_1_2_7_114_1 doi: 10.1002/cncr.26677 – ident: e_1_2_7_124_1 doi: 10.1002/cncr.33649 – ident: e_1_2_7_42_1 doi: 10.1056/nejmoa1301969 – ident: e_1_2_7_79_1 doi: 10.1002/cncr.32163 – ident: e_1_2_7_41_1 doi: 10.1016/j.cgh.2016.10.038 – ident: e_1_2_7_21_1 – ident: e_1_2_7_74_1 doi: 10.1016/j.jss.2015.10.021 – ident: e_1_2_7_71_1 doi: 10.1200/jco.2007.14.5631 – ident: e_1_2_7_76_1 doi: 10.1016/j.critrevonc.2016.11.005 – ident: e_1_2_7_133_1 doi: 10.1001/jama.2021.4417 – ident: e_1_2_7_35_1 – ident: e_1_2_7_57_1 doi: 10.1136/gutjnl‐2020‐323450 – ident: e_1_2_7_78_1 doi: 10.1200/jco.2008.20.5278 – ident: e_1_2_7_108_1 doi: 10.1007/s10620‐010‐1528‐3 – ident: e_1_2_7_28_1 doi: 10.1002/cncr.34390 – ident: e_1_2_7_67_1 doi: 10.6004/jnccn.2022.7056 – ident: e_1_2_7_91_1 doi: 10.1093/jnci/dju427 – ident: e_1_2_7_127_1 doi: 10.3322/caac.20121 – ident: e_1_2_7_55_1 doi: 10.1038/ncomms7342 – ident: e_1_2_7_12_1 doi: 10.3322/caac.21757 – ident: e_1_2_7_75_1 doi: 10.1002/jso.21864 – ident: e_1_2_7_144_1 doi: 10.1038/ajg.2012.161 – volume: 5 start-page: 149 issue: 5 year: 2012 ident: e_1_2_7_103_1 article-title: Colorectal cancer in Alaska Native people, 2005‐2009 publication-title: Gastrointest Cancer Res – volume-title: National Health Interview Survey Public Use Data File 2021 year: 2019 ident: e_1_2_7_33_1 – ident: e_1_2_7_122_1 doi: 10.1053/j.gastro.2017.11.005 – ident: e_1_2_7_72_1 doi: 10.3322/caac.21731 – volume-title: Cancer in Alaska Native People: 1969‐2018, The 50‐Year Report year: 2021 ident: e_1_2_7_100_1 – ident: e_1_2_7_111_1 doi: 10.1053/j.gastro.2019.10.029 – ident: e_1_2_7_31_1 doi: 10.1097/01.mlr.0000246612.35245.21 – ident: e_1_2_7_59_1 doi: 10.1002/cncr.31994 – ident: e_1_2_7_131_1 doi: 10.1002/cncr.31543 – ident: e_1_2_7_44_1 doi: 10.1093/oxfordjournals.aje.a116143 – volume-title: SEER*Stat software, version 8.4.0 year: 2022 ident: e_1_2_7_17_1 – ident: e_1_2_7_7_1 – ident: e_1_2_7_46_1 doi: 10.1146/annurev.pu.12.050191.002233 – ident: e_1_2_7_14_1 doi: 10.1158/1055-9965.EPI-20-1780 – ident: e_1_2_7_142_1 doi: 10.1371/journal.pone.0244431 – ident: e_1_2_7_143_1 doi: 10.1158/1055‐9965.EPI‐22‐0527 – ident: e_1_2_7_109_1 doi: 10.1016/j.amjsurg.2019.09.027 – ident: e_1_2_7_43_1 doi: 10.1136/gutjnl‐2016‐312712 – ident: e_1_2_7_81_1 doi: 10.1001/jama.2021.0106 – ident: e_1_2_7_99_1 doi: 10.1016/j.jcpo.2021.100293 – ident: e_1_2_7_117_1 doi: 10.1200/jco.2017.74.2049 – ident: e_1_2_7_123_1 doi: 10.1158/1055‐9965.epi‐20‐0950 – ident: e_1_2_7_53_1 doi: 10.1136/bmj‐2021‐068921 – ident: e_1_2_7_120_1 doi: 10.1007/s40615‐015‐0174‐z – ident: e_1_2_7_83_1 doi: 10.1007/s10552‐014‐0344‐z – ident: e_1_2_7_68_1 doi: 10.1093/jnci/djab123 – ident: e_1_2_7_107_1 doi: 10.1053/j.gastro.2018.09.054 – volume: 70 start-page: 1 issue: 12 year: 2021 ident: e_1_2_7_9_1 article-title: Mortality profile of the non‐Hispanic American Indian or Alaska Native population, 2019 publication-title: Natl Vital Stat Rep – ident: e_1_2_7_36_1 doi: 10.3322/canjclin.30.4.208 – ident: e_1_2_7_134_1 doi: 10.1016/j.cgh.2022.04.037
SSID	ssj0000777
Score	2.7662103
Snippet	Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of...
SourceID	proquest pubmed crossref wiley
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	233
SubjectTerms	American Cancer Society Cancer colon and rectum neoplasms Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Diagnosis early‐onset colorectal cancer epidemiology health disparities Humans Incidence Mortality Native North Americans Rectal Neoplasms screening and early detection Statistics United States - epidemiology
Title	Colorectal cancer statistics, 2023
URI	https://onlinelibrary.wiley.com/doi/abs/10.3322%2Fcaac.21772 https://www.ncbi.nlm.nih.gov/pubmed/36856579 https://www.proquest.com/docview/2811025718 https://www.proquest.com/docview/2781214958
Volume	73
WOSCitedRecordID	wos000940400800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVWIB databaseName: Wiley Online Library Open Access customDbUrl: eissn: 1542-4863 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000777 issn: 0007-9235 databaseCode: WIN dateStart: 19970101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell – providerCode: PRVWIB databaseName: Wiley Online Library Open Access customDbUrl: eissn: 1542-4863 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000777 issn: 0007-9235 databaseCode: 24P dateStart: 19970101 isFulltext: true titleUrlDefault: https://authorservices.wiley.com/open-science/open-access/browse-journals.html providerName: Wiley-Blackwell
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LS8NAEB6Kinjx_YhWiY-LYrBJNtkNeCnBoqClBx-9hWR2c5JUqvX3O5OkKUURxByWQCZsNvPYb7LZbwDOECUvigYOGk0JCmLmZDpDB4OORhUYDMuSLM_3st9Xw2E0aMH1dC9MxQ_RfHBjzyjjNTt4mpVVSHyyQVIiptQhAWpJAXjRdX3JNu2JwSwOS1kxZnakQzAmqMhJ-e6r2b3z09E3jDkPWcs5p7f2v6ddh9Uaa9rdyjg2oGWKTVh-qFfTt-AkpsjHEY-EkLU_tnl_UUXdfGlzyfNteOrdPMa3Tl0zwUERRJ7jaeXmBmVOMEMYIX1jpMgiRmWZ8o2gw8-kDnOaHFMvF1qoXLkmzCmvQVTS34GFYlSYPbAJWBGWSvNQIYpIpxET8RBgyWWoU0piLTifvroEa0JxrmvxmlBiwcNOeNBJOWgLThvZt4pG40ep9lQDSe1K74mnCKFQYHGVBcfNZXICXtlICzOakIwknMK5HsnsVpprumGGfTK4yIKLUkG_9J_E3W5cnu3_RfgAVlgj1W-QbVj4GE_MISzhJylsfFQaJbVyqKh9uet_Acqf4jY
linkProvider	Wiley-Blackwell
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT4NAEJ4YNerF9wOtio-LRmILC7scG2JTY9v0UE1vBIbdk2lNtf5-Z4DSNBoTIycShizLPPabfXwDcI0oeVHUd1BnlKAgpk6apeigX89Q-RqDvCTLS0f2emo4DPvl3hw-C1PwQ1QTbuwZebxmB-cJafZyj4yQtIgJtUiIWlIEXhE0zHABA1f054FYyoIysy4dwjF-wU7Kb9_P310cj76BzEXMmg86ra1_fu42bJZo024W5rEDS3q0C2vdcj19Dy4jin0c80gIWf8Tm08YFeTNdzYXPd-H59bDIGo7ZdUEB4Ufuo6bqYbRKA0BDaGF9LSWIg0Zl6XK04IuL5VZYGh4TFwjMqGMaujAUGaDqKR3AMuj8UgfgU3QitBUYgKFKMIsCZmKhyCLkUGWUBprwc3s38VYUopzZYvXmFIL7nbMnY7zTltwVcm-FUQaP0rVZiqIS2d6j11FGIVCS0NZcFE9JjfgtY1kpMdTkpGEVDjbI5nDQnVVM8yxTyYXWnCba-iX9uOo2Yzyu-O_CJ_DenvQ7cSdx97TCWywdopNkTVY_phM9Sms4icpb3KWW-gXm3LkIQ
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LS8NAEB6kSvHi-1GtGh8XxWCbbLKbY4kWxVp6UOktJLO7J2lLtf5-Z5K0pSiCmFMgs2w289hvsrvfAFwgSl4UDVw0mhIUxMzNdIYuBg2NKjAY5iVZXjuy21X9ftQr9-bwWZiCH2L2w409I4_X7OBmpC17uU9GSFrElHokRC0pAi-LgIIsEzuL3jwQS1lQZjakSzgmKNhJufXNvO3ifPQNZC5i1nzSaa__83U3YK1Em06rMI9NWDKDLag-levp23AWU-zjmEdCyPofO3zCqCBvvna46PkOvLTvnuN7t6ya4KIIIs_1tGpag9IS0BBGSN8YKbKIcVmmfCPo8jOpQ0vTY-pZoYWyqmlCS5kNopL-LlQGw4HZB4egFaGp1IYKUUQ6jZiKhyCLlaFOKY2tweX02yVYUopzZYu3hFILHnbCg07yQdfgfCY7Kog0fpSqT1WQlM70nniKMIrHCq7B6ewxuQGvbaQDM5yQjCSkwtkeyewVqpt1wxz7ZHJRDa5yDf3SfxK3WnF-d_AX4ROo9m7bSeeh-3gIq6ycYk9kHSof44k5ghX8JN2Nj3MD_QJl3eOl
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Colorectal+cancer+statistics%2C+2023&rft.jtitle=CA%3A+a+cancer+journal+for+clinicians&rft.au=Siegel%2C+Rebecca+L&rft.au=Wagle%2C+Nikita+Sandeep&rft.au=Cercek%2C+Andrea&rft.au=Smith%2C+Robert+A&rft.date=2023-05-01&rft.pub=Wiley+Subscription+Services%2C+Inc&rft.issn=0007-9235&rft.eissn=1542-4863&rft.volume=73&rft.issue=3&rft.spage=233&rft_id=info:doi/10.3322%2Fcaac.21772&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0007-9235&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0007-9235&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0007-9235&client=summon