Endoscopic sleeve gastroplasty: a potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity

Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic app...

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Bibliographic Details
Published in:Gastrointestinal endoscopy Vol. 78; no. 3; pp. 530 - 535
Main Authors: Abu Dayyeh, Barham K., Rajan, Elizabeth, Gostout, Christopher J.
Format: Journal Article
Language:English
Published: United States Mosby, Inc 01.09.2013
Subjects:
Adult
Endoscopy, Gastrointestinal - adverse effects
Endoscopy, Gastrointestinal - instrumentation
Endoscopy, Gastrointestinal - methods
Feasibility Studies
Female
Gastroenterology and Hepatology
Gastroplasty - adverse effects
Gastroplasty - instrumentation
Gastroplasty - methods
Humans
Male
Middle Aged
Obesity - surgery
Operative Time
Organ Size
Pain, Postoperative - etiology
Stomach - anatomy & histology
Stomach - surgery
Suture Techniques - adverse effects
Suture Techniques - instrumentation
SD
GE
GIWLS
gastroesophageal
GI weight loss surgery
standard deviation
ISSN:0016-5107, 1097-6779, 1097-6779
Online Access:Get full text
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Summary:Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic approaches to reproduce many of the benefits of GI weight loss surgery and thereby contribute to the effective treatment of obesity and its associated disorders. To demonstrate the technical feasibility of transoral endoscopic gastric volume reduction with an endoscopic suturing device in a fashion similar to sleeve gastrectomy for the treatment of obesity. Single-center, pilot feasibility study. Four human subjects with obesity. Transoral sleeve gastroplasty. Technical feasibility. We successfully used an endoscopic free-hand suturing system in 4 subjects, thus demonstrating the technical feasibility of a novel technique to mimic the anatomic manipulations created by surgical sleeve gastrectomy endoscopically. Pilot feasibility study with small number of subjects. Endoscopic sleeve gastroplasty for treatment of obesity is feasible.
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ISSN:0016-5107
1097-6779
1097-6779
DOI:10.1016/j.gie.2013.04.197