Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015‐2018
Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance...
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| Vydané v: | Contact dermatitis Ročník 84; číslo 2; s. 109 - 120 |
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| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Oxford, UK
Blackwell Publishing Ltd
01.02.2021
Wiley Subscription Services, Inc |
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| ISSN: | 0105-1873, 1600-0536, 1600-0536 |
| On-line prístup: | Získať plný text |
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| Abstract | Background
Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.
Objectives
To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.
Methods
Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.
Results
In the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).
Conclusions
While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS. |
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| AbstractList | BackgroundClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.ObjectivesTo present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.MethodsAnonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.ResultsIn the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).ConclusionsWhile the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS. Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Methods Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. Results In the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%). Conclusions While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS. Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.BACKGROUNDClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.OBJECTIVESTo present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.METHODSAnonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).RESULTSIn the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.CONCLUSIONSWhile the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS. Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%). While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS. |
| Author | Pesonen, Maria Beiteke, Ulrike Werfel, Thomas Filon, Francesca Larese Gallo, Rosella Godnič, Mojca Simončič Dietrich, Cecilia Valiukevičienė, Skaidra Grabbe, Jürgen Dickel, Heinrich Chowdhury, Mahbub M. White, Ian R. Kecelj, Nada Sadowska‐Przytocka, Anna Aberer, Werner Dugonik, Aleksandra Giménez‐Arnau, Ana M. Gonçalo, Margarida Ballmer‐Weber, Barbara John, Swen Malte Wagner, Nicola Johnston, Graham A. Mercader, Pedro Vok, Marko Buhl, Timo Uter, Wolfgang Weisshaar, Elke Corradin, Maria Teresa Geier, Johannes Brans, Richard Bauer, Andrea Lunder, Tomaž Becker, Detlef Bircher, Andreas J. Pandurovic, Maja Kalac Belloni Fortina, Anna Ruiz, Inmaculada Schliemann, Sibylle Czarnecka‐Operacz, Magdalena Stingeni, Luca Rustemeyer, Thomas Stone, Natalie Scherer‐Hofmeier, Kathrin Sanchez‐Perez, Javier Johansen, Jeanne D. Wilkinson, Mark Kmecl, Tanja Peserico, Andrea Kränke, Birger Schuttelaar, Marie L.A. Spiewak, Radoslaw Cooper, Susan M. Navarini, Alexander Simon, Dagmar Brasch, Jochen Mahler, Vera |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32945543$$D View this record in MEDLINE/PubMed |
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| ContentType | Journal Article |
| Contributor | Becker, Detlef Pesonen, Maria Beiteke, Ulrike Werfel, Thomas Filon, Francesca Larese Pandurovic, Maja Kalac Gallo, Rosella Godnič, Mojca Simončič Dietrich, Cecilia Ruiz, Inmaculada Grabbe, Jürgen Schliemann, Sibylle Stingeni, Luca Stone, Natalie Ballmer-Weber, Barbara Kecelj, Nada Scherer-Hofmeier, Kathrin Aberer, Werner Chowdhury, Mahbub M Kmecl, Tanja Peserico, Andrea John, Swen Malte Wagner, Nicola Kränke, Birger Mercader, Pedro Vok, Marko Corradin, Maria Teresa Sadowska-Przytocka, Anna Navarini, Alexander Brasch, Jochen Lunder, Tomaž |
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| Copyright | 2020 The Authors. published by John Wiley & Sons Ltd. 2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. 2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
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| ISSN | 0105-1873 1600-0536 |
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| Issue | 2 |
| Keywords | contact allergy surveillance RRID:SCR_001905 patch testing clinical epidemiology |
| Language | English |
| License | Attribution 2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. |
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| Notes | Funding information Collaborators: ESSCA working group: Werner Aberer, Department of Dermatology, Medical University of Graz, Graz, Austria; Barbara Ballmer‐Weber, Department of Dermatology, University Hospital Zürich and Clinic of Dermatology and Allergology, Kantonsspital St. Gallen, Zürich, Switzerland; Detlef Becker, Department of Dermatology, University of Mainz, Mainz, Germany; Ulrike Beiteke, Department of Dermatology, Dortmund, Germany; Jochen Brasch, Department of Dermatology, University of Schleswig‐Holstein, Campus Kiel, Kiel, Germany; Mahbub M. Chowdhury, Welsh Institute of Dermatology, Cardiff, UK; Maria Teresa Corradin, Dermatology Unit, Santa Maria degli Angeli Hospital, Pordenone, Italy; Cecilia Dietrich, Department of Dermatology, University of Schleswig‐Holstein, Campus Kiel, Kiel, Germany; Rosella Gallo, Clinica Dermatologica, IRCCS – AOU San Martino – IST and Department of Health Sciences, University of Genoa, Genoa, Italy; Jürgen Grabbe, Department of Dermatology, Kantonsspital Aarau, Aarau, Switzerland; Swen Malte John, Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), University of Osnabrück, Lower Saxony Institute for Occupational Dermatology (NIB), Osnabrück, Germany; Maja Kalac Pandurovic, Outpatient Clinic of Dermatology, Maribor, Maribor, Slovenia; Nada Kecelj, Outpatient Clinic of Dermatology, Ljubljana, Slovenia; Tanja Kmecl, Department of Dermatology, General Hospital Celje, Celje, Slovenia; Birger Kränke, Department of Dermatology, Medical University of Graz, Graz, Austria; Francesca Larese Filon, Department of Public Health, Occupational Medicine, University of Trieste, Trieste, Italy; Tomaž Lunder, Department of Dermatology, University Medical Center, Ljubljana, Slovenia; Pedro Mercader, Dermatology Department, Hospital General Universitario Morales Meseguer, Murcia, Spain; Alexander Navarini, Department of Dermatology, University Hospital Zürich, Zürich, Switzerland; Andrea Peserico, Department of Dermatology, University of Padova, Padova, Italy; Maria Pesonen, Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland; Inmaculada Ruiz, Department of Dermatology, Complejo Asistencial de León, León, Spain; Anna Sadowska‐Przytocka, Department of Dermatology, Poznań University of Medical Sciences, Poznań, Poland; Kathrin Scherer‐Hofmeier, Allergy Unit, Dept. of Dermatology, University Hospital Basel, Basel, Switzerland; Sibylle Schliemann, Department of Dermatology and Allergology, University Hospital Jena, Jena, Germany; Mojca Simončič Godnič, Department of Dermatology, Novo Mesto, Slovenia; Luca Stingeni, Dermatology Section, Department of Medicine, University of Perugia, Perugia, Italy; Natalie Stone, Aneurin Bevin Health Board, Newport, Gwent, UK; Marko Vok, Outpatient Clinic of Dermatology, Izola, Slovenia; Nicola Wagner, Department of Dermatology, University of Erlangen‐Nürnberg, Erlangen, Germany; Thomas Werfel, Medizinische Hochschule Hannover, Department of Immunodermatology and Experimental Allergy, Hannover, Germany. Partial funding by EADV Grant PPRC‐2018‐8 Funding Information: Partial funding by EADV Grant PPRC‐2018‐8. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-4411-3088 0000-0001-6471-1811 0000-0002-3537-8463 0000-0001-5968-0555 0000-0002-4498-3710 0000-0002-5047-8948 0000-0001-5791-0775 0000-0001-7580-0684 0000-0001-8965-9407 0000-0001-6842-1360 0000-0002-3139-129X |
| OpenAccessLink | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fcod.13704 |
| PMID | 32945543 |
| PQID | 2480151857 |
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| PageCount | 12 |
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| PublicationCentury | 2000 |
| PublicationDate | February 2021 |
| PublicationDateYYYYMMDD | 2021-02-01 |
| PublicationDate_xml | – month: 02 year: 2021 text: February 2021 |
| PublicationDecade | 2020 |
| PublicationPlace | Oxford, UK |
| PublicationPlace_xml | – name: Oxford, UK – name: England – name: Malden |
| PublicationTitle | Contact dermatitis |
| PublicationTitleAlternate | Contact Dermatitis |
| PublicationYear | 2021 |
| Publisher | Blackwell Publishing Ltd Wiley Subscription Services, Inc |
| Publisher_xml | – name: Blackwell Publishing Ltd – name: Wiley Subscription Services, Inc |
| References | 2018; 29 2013; 69 2015; 73 2009; 61 2019; 33 2020; 82 2011; 84 2000; 42 2016; 75 2008; 59 2020; 34 2016; 14 1996; 34 2016; 55 2017; 31 2019; 80 2019; 81 2019; 181 2003; 149 2020 1997; 37 2017; 77 2017; 76 2005; 53 2011; 66 2003; 49 2011; 65 2008; 22 2008; 159 2018; 78 2012; 67 2014; 71 2017; 202 2016; 25 2005; 14 e_1_2_9_31_1 e_1_2_9_52_1 e_1_2_9_50_1 e_1_2_9_10_1 e_1_2_9_12_1 e_1_2_9_33_1 e_1_2_9_54_1 e_1_2_9_14_1 e_1_2_9_39_1 e_1_2_9_16_1 e_1_2_9_37_1 e_1_2_9_58_1 e_1_2_9_41_1 e_1_2_9_20_1 e_1_2_9_22_1 e_1_2_9_45_1 e_1_2_9_24_1 e_1_2_9_43_1 e_1_2_9_8_1 e_1_2_9_6_1 e_1_2_9_4_1 Uter W (e_1_2_9_2_1) 2020 e_1_2_9_26_1 e_1_2_9_28_1 e_1_2_9_47_1 Kirchlechner S (e_1_2_9_49_1) 2016; 14 e_1_2_9_30_1 e_1_2_9_53_1 e_1_2_9_51_1 e_1_2_9_11_1 e_1_2_9_34_1 e_1_2_9_57_1 e_1_2_9_13_1 e_1_2_9_32_1 e_1_2_9_55_1 Whitehouse H (e_1_2_9_56_1) 2020 e_1_2_9_15_1 e_1_2_9_38_1 e_1_2_9_17_1 e_1_2_9_36_1 e_1_2_9_59_1 e_1_2_9_19_1 Anon (e_1_2_9_35_1) 2017; 202 e_1_2_9_42_1 e_1_2_9_40_1 e_1_2_9_21_1 e_1_2_9_46_1 e_1_2_9_23_1 e_1_2_9_44_1 e_1_2_9_7_1 e_1_2_9_5_1 e_1_2_9_3_1 e_1_2_9_9_1 e_1_2_9_25_1 e_1_2_9_27_1 e_1_2_9_48_1 e_1_2_9_29_1 ESSCA writing group (e_1_2_9_18_1) 2008; 22 |
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Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the... Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance... BackgroundClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the... |
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| SubjectTerms | Allergens Allergies clinical epidemiology contact allergy Haptens Heavy metals Nickel patch testing Preservatives Quality control RRID:SCR_001905 Surveillance |
| Title | Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015‐2018 |
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