Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015‐2018

Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance...

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Vydané v:Contact dermatitis Ročník 84; číslo 2; s. 109 - 120
Hlavní autori: Uter, Wolfgang, Bauer, Andrea, Belloni Fortina, Anna, Bircher, Andreas J., Brans, Richard, Buhl, Timo, Cooper, Susan M., Czarnecka‐Operacz, Magdalena, Dickel, Heinrich, Dugonik, Aleksandra, Geier, Johannes, Giménez‐Arnau, Ana M., Gonçalo, Margarida, Johansen, Jeanne D., Johnston, Graham A., Mahler, Vera, Rustemeyer, Thomas, Sanchez‐Perez, Javier, Schuttelaar, Marie L.A., Simon, Dagmar, Spiewak, Radoslaw, Valiukevičienė, Skaidra, Weisshaar, Elke, White, Ian R., Wilkinson, Mark, Aberer, Werner, Ballmer‐Weber, Barbara, Becker, Detlef, Beiteke, Ulrike, Brasch, Jochen, Chowdhury, Mahbub M., Corradin, Maria Teresa, Dietrich, Cecilia, Gallo, Rosella, Grabbe, Jürgen, John, Swen Malte, Pandurovic, Maja Kalac, Kecelj, Nada, Kmecl, Tanja, Kränke, Birger, Filon, Francesca Larese, Lunder, Tomaž, Mercader, Pedro, Navarini, Alexander, Peserico, Andrea, Pesonen, Maria, Ruiz, Inmaculada, Sadowska‐Przytocka, Anna, Scherer‐Hofmeier, Kathrin, Schliemann, Sibylle, Godnič, Mojca Simončič, Stingeni, Luca, Stone, Natalie, Vok, Marko, Wagner, Nicola, Werfel, Thomas
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Oxford, UK Blackwell Publishing Ltd 01.02.2021
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ISSN:0105-1873, 1600-0536, 1600-0536
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Abstract Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Methods Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. Results In the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%). Conclusions While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
AbstractList BackgroundClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.ObjectivesTo present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.MethodsAnonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.ResultsIn the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).ConclusionsWhile the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Methods Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. Results In the 4 years (2015‐2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%). Conclusions While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.BACKGROUNDClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.OBJECTIVESTo present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.METHODSAnonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).RESULTSIn the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.CONCLUSIONSWhile the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%). While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
Author Pesonen, Maria
Beiteke, Ulrike
Werfel, Thomas
Filon, Francesca Larese
Gallo, Rosella
Godnič, Mojca Simončič
Dietrich, Cecilia
Valiukevičienė, Skaidra
Grabbe, Jürgen
Dickel, Heinrich
Chowdhury, Mahbub M.
White, Ian R.
Kecelj, Nada
Sadowska‐Przytocka, Anna
Aberer, Werner
Dugonik, Aleksandra
Giménez‐Arnau, Ana M.
Gonçalo, Margarida
Ballmer‐Weber, Barbara
John, Swen Malte
Wagner, Nicola
Johnston, Graham A.
Mercader, Pedro
Vok, Marko
Buhl, Timo
Uter, Wolfgang
Weisshaar, Elke
Corradin, Maria Teresa
Geier, Johannes
Brans, Richard
Bauer, Andrea
Lunder, Tomaž
Becker, Detlef
Bircher, Andreas J.
Pandurovic, Maja Kalac
Belloni Fortina, Anna
Ruiz, Inmaculada
Schliemann, Sibylle
Czarnecka‐Operacz, Magdalena
Stingeni, Luca
Rustemeyer, Thomas
Stone, Natalie
Scherer‐Hofmeier, Kathrin
Sanchez‐Perez, Javier
Johansen, Jeanne D.
Wilkinson, Mark
Kmecl, Tanja
Peserico, Andrea
Kränke, Birger
Schuttelaar, Marie L.A.
Spiewak, Radoslaw
Cooper, Susan M.
Navarini, Alexander
Simon, Dagmar
Brasch, Jochen
Mahler, Vera
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/32945543$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
Contributor Becker, Detlef
Pesonen, Maria
Beiteke, Ulrike
Werfel, Thomas
Filon, Francesca Larese
Pandurovic, Maja Kalac
Gallo, Rosella
Godnič, Mojca Simončič
Dietrich, Cecilia
Ruiz, Inmaculada
Grabbe, Jürgen
Schliemann, Sibylle
Stingeni, Luca
Stone, Natalie
Ballmer-Weber, Barbara
Kecelj, Nada
Scherer-Hofmeier, Kathrin
Aberer, Werner
Chowdhury, Mahbub M
Kmecl, Tanja
Peserico, Andrea
John, Swen Malte
Wagner, Nicola
Kränke, Birger
Mercader, Pedro
Vok, Marko
Corradin, Maria Teresa
Sadowska-Przytocka, Anna
Navarini, Alexander
Brasch, Jochen
Lunder, Tomaž
Contributor_xml – sequence: 1
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  surname: Aberer
  fullname: Aberer, Werner
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  givenname: Jochen
  surname: Brasch
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  givenname: Mahbub M
  surname: Chowdhury
  fullname: Chowdhury, Mahbub M
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  givenname: Maria Teresa
  surname: Corradin
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Copyright 2020 The Authors. published by John Wiley & Sons Ltd.
2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
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Issue 2
Keywords contact allergy
surveillance
RRID:SCR_001905
patch testing
clinical epidemiology
Language English
License Attribution
2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
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Notes Funding information
Collaborators: ESSCA working group: Werner Aberer, Department of Dermatology, Medical University of Graz, Graz, Austria; Barbara Ballmer‐Weber, Department of Dermatology, University Hospital Zürich and Clinic of Dermatology and Allergology, Kantonsspital St. Gallen, Zürich, Switzerland; Detlef Becker, Department of Dermatology, University of Mainz, Mainz, Germany; Ulrike Beiteke, Department of Dermatology, Dortmund, Germany; Jochen Brasch, Department of Dermatology, University of Schleswig‐Holstein, Campus Kiel, Kiel, Germany; Mahbub M. Chowdhury, Welsh Institute of Dermatology, Cardiff, UK; Maria Teresa Corradin, Dermatology Unit, Santa Maria degli Angeli Hospital, Pordenone, Italy; Cecilia Dietrich, Department of Dermatology, University of Schleswig‐Holstein, Campus Kiel, Kiel, Germany; Rosella Gallo, Clinica Dermatologica, IRCCS – AOU San Martino – IST and Department of Health Sciences, University of Genoa, Genoa, Italy; Jürgen Grabbe, Department of Dermatology, Kantonsspital Aarau, Aarau, Switzerland; Swen Malte John, Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), University of Osnabrück, Lower Saxony Institute for Occupational Dermatology (NIB), Osnabrück, Germany; Maja Kalac Pandurovic, Outpatient Clinic of Dermatology, Maribor, Maribor, Slovenia; Nada Kecelj, Outpatient Clinic of Dermatology, Ljubljana, Slovenia; Tanja Kmecl, Department of Dermatology, General Hospital Celje, Celje, Slovenia; Birger Kränke, Department of Dermatology, Medical University of Graz, Graz, Austria; Francesca Larese Filon, Department of Public Health, Occupational Medicine, University of Trieste, Trieste, Italy; Tomaž Lunder, Department of Dermatology, University Medical Center, Ljubljana, Slovenia; Pedro Mercader, Dermatology Department, Hospital General Universitario Morales Meseguer, Murcia, Spain; Alexander Navarini, Department of Dermatology, University Hospital Zürich, Zürich, Switzerland; Andrea Peserico, Department of Dermatology, University of Padova, Padova, Italy; Maria Pesonen, Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland; Inmaculada Ruiz, Department of Dermatology, Complejo Asistencial de León, León, Spain; Anna Sadowska‐Przytocka, Department of Dermatology, Poznań University of Medical Sciences, Poznań, Poland; Kathrin Scherer‐Hofmeier, Allergy Unit, Dept. of Dermatology, University Hospital Basel, Basel, Switzerland; Sibylle Schliemann, Department of Dermatology and Allergology, University Hospital Jena, Jena, Germany; Mojca Simončič Godnič, Department of Dermatology, Novo Mesto, Slovenia; Luca Stingeni, Dermatology Section, Department of Medicine, University of Perugia, Perugia, Italy; Natalie Stone, Aneurin Bevin Health Board, Newport, Gwent, UK; Marko Vok, Outpatient Clinic of Dermatology, Izola, Slovenia; Nicola Wagner, Department of Dermatology, University of Erlangen‐Nürnberg, Erlangen, Germany; Thomas Werfel, Medizinische Hochschule Hannover, Department of Immunodermatology and Experimental Allergy, Hannover, Germany.
Partial funding by EADV Grant PPRC‐2018‐8
Funding Information: Partial funding by EADV Grant PPRC‐2018‐8.
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Snippet Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the...
Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance...
BackgroundClinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the...
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StartPage 109
SubjectTerms Allergens
Allergies
clinical epidemiology
contact allergy
Haptens
Heavy metals
Nickel
patch testing
Preservatives
Quality control
RRID:SCR_001905
Surveillance
Title Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015‐2018
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fcod.13704
https://www.ncbi.nlm.nih.gov/pubmed/32945543
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Volume 84
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