Scaling laws of bacterial and archaeal plasmids

The capacity of a plasmid to express genes is constrained by its length and copy number. However, the interplay between these parameters and their constraints on plasmid evolution have remained elusive due to the absence of comprehensive quantitative analyses. Here, we present ‘Pseudoalignment and P...

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Bibliographic Details
Published in:	Nature communications Vol. 16; no. 1; pp. 6023 - 14
Main Authors:	Maddamsetti, Rohan, Shyti, Irida, Wilson, Maggie L., Son, Hye-In, Baig, Yasa, Zhou, Zhengqing, Lu, Jia, You, Lingchong
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 02.07.2025 Nature Publishing Group Nature Portfolio
Subjects:	45 631/114/2409 631/181 631/208/212/2305 631/326/41 631/326/41/2530 Archaea - genetics Bacteria Bacteria - genetics Biology Chromosomes Computational Biology - methods Computer applications Constraints Copy number Correlation Datasets Estimates Evolution Evolution, Molecular Functional morphology Gene Dosage Gene expression Genes Genetic engineering Genome, Archaeal - genetics Genome, Bacterial - genetics Genomes Genomics Humanities and Social Sciences Microorganisms multidisciplinary Parameters Plasmids Plasmids - genetics Scaling Scaling laws Science Science (multidisciplinary)
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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