Statistical Properties of the Branch-Site Test of Positive Selection

The branch-site test is a likelihood ratio test to detect positive selection along prespecified lineages on a phylogeny that affects only a subset of codons in a protein-coding gene, with positive selection indicated by accelerated nonsynonymous substitutions (with ω = dN/dS > 1). This test may h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology and evolution Jg. 28; H. 3; S. 1217 - 1228
Hauptverfasser:	Yang, Ziheng, dos Reis, Mario
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Society for Molecular Biology and Evolution 01.03.2011 Oxford University Press
Schlagworte:	Animals Codon Computer simulation Computer Simulation - statistics & numerical data Evolution, Molecular Genes Genome Genomics - statistics & numerical data Humans Likelihood Functions Models, Genetic Molecular biology Mutation Open Reading Frames - genetics Phylogenetics Phylogeny Proteins Selection, Genetic Sequence Alignment likelihood ratio test positive selection codon model branch-site test
ISSN:	0737-4038, 1537-1719, 1537-1719
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!