Statistical Properties of the Branch-Site Test of Positive Selection

The branch-site test is a likelihood ratio test to detect positive selection along prespecified lineages on a phylogeny that affects only a subset of codons in a protein-coding gene, with positive selection indicated by accelerated nonsynonymous substitutions (with ω = dN/dS > 1). This test may h...

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Vydané v:	Molecular biology and evolution Ročník 28; číslo 3; s. 1217 - 1228
Hlavní autori:	Yang, Ziheng, dos Reis, Mario
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Society for Molecular Biology and Evolution 01.03.2011 Oxford University Press
Predmet:	Animals Codon Computer simulation Computer Simulation - statistics & numerical data Evolution, Molecular Genes Genome Genomics - statistics & numerical data Humans Likelihood Functions Models, Genetic Molecular biology Mutation Open Reading Frames - genetics Phylogenetics Phylogeny Proteins Selection, Genetic Sequence Alignment likelihood ratio test positive selection codon model branch-site test
ISSN:	0737-4038, 1537-1719, 1537-1719
On-line prístup:	Získať plný text
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