Involvement of inositol 1,4,5-trisphosphate in nicotinic calcium responses in dystrophic myotubes assessed by near-plasma membrane calcium measurement

In skeletal muscle cells, plasma membrane depolarization causes a rapid calcium release from the sarcoplasmic reticulum through ryanodine receptors triggering contraction. In Duchenne muscular dystrophy (DMD), a lethal disease that is caused by the lack of the cytoskeletal protein dystrophin, the cy...

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Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 279; no. 45; p. 47092
Main Authors:	Basset, Olivier, Boittin, François-Xavier, Dorchies, Olivier M, Chatton, Jean-Yves, van Breemen, Cornelis, Ruegg, Urs T
Format:	Journal Article
Language:	English
Published:	United States 05.11.2004
Subjects:	Aequorin - chemistry Animals Calcium - chemistry Calcium - metabolism Calcium Channels - metabolism Carbachol - pharmacology Cell Membrane - metabolism Cholinergic Agonists - pharmacology Cytosol - metabolism Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Green Fluorescent Proteins - metabolism Inositol 1,4,5-Trisphosphate - physiology Inositol 1,4,5-Trisphosphate Receptors Membrane Proteins - metabolism Mice Mice, Inbred C57BL Microscopy, Confocal Muscle, Skeletal - metabolism Myocardium - metabolism Necrosis Nerve Tissue Proteins - metabolism Phosphoproteins - chemistry Plasmids - metabolism Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Nicotinic - metabolism Sarcoplasmic Reticulum - metabolism Synaptosomal-Associated Protein 25 Time Factors Transfection
ISSN:	0021-9258
Online Access:	Get more information
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