Line-Field Confocal Optical Coherence Tomography (LC-OCT) for Skin Imaging in Dermatology

Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive optical imaging technique based on a combination of the principles of optical coherence tomography and reflectance confocal microscopy with line-field illumination, which can generate cell-resolved images of the skin in vivo...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Vol. 13; no. 12; p. 2268
Main Authors: Latriglia, Flora, Ogien, Jonas, Tavernier, Clara, Fischman, Sébastien, Suppa, Mariano, Perrot, Jean-Luc, Dubois, Arnaud
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 28.11.2023
MDPI
Subjects:
3D reconstruction
Algorithms
Basal cell carcinoma
Biopsy
Confocal microscopy
Deep learning
Dermatology
dermoscopy
Imaging techniques
In vivo methods and tests
Inflammation
Invasiveness
Keratosis
Lesions
Life Sciences
line-field confocal optical coherence tomography (LC-OCT)
Machine learning
Medical equipment
Melanoma
Microscopy
Oncology
Optical Coherence Tomography
optical coherence tomography (OCT)
Physics
Principles
Skin
Skin cancer
Skin diseases
skin imaging
Skin lesions
Squamous cell carcinoma
Technological change
Tomography
Ultrasonic imaging
United States > US
Germany
3D reconstruction
dermatology
skin imaging
line-field confocal optical coherence tomography (LC-OCT)
confocal microscopy
optical coherence tomography (OCT)
artificial intelligence
dermoscopy
optical coherence tomography (OCT) line-field confocal optical coherence tomography (LC-OCT) confocal microscopy 3D reconstruction dermoscopy skin imaging dermatology artificial intelligence
ISSN:2075-1729, 2075-1729
Online Access:Get full text
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Description
Summary:Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive optical imaging technique based on a combination of the principles of optical coherence tomography and reflectance confocal microscopy with line-field illumination, which can generate cell-resolved images of the skin in vivo. This article reports on the LC-OCT technique and its application in dermatology. The principle of the technique is described, and the latest technological innovations are presented. The technology has been miniaturized to fit within an ergonomic handheld probe, allowing for the easy access of any skin area on the body. The performance of the LC-OCT device in terms of resolution, field of view, and acquisition speed is reported. The use of LC-OCT in dermatology for the non-invasive detection, characterization, and therapeutic follow-up of various skin pathologies is discussed. Benign and malignant melanocytic lesions, non-melanocytic skin tumors, such as basal cell carcinoma, squamous cell carcinoma and actinic keratosis, and inflammatory and infectious skin conditions are considered. Dedicated deep learning algorithms have been developed for assisting in the analysis of LC-OCT images of skin lesions.
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ISSN:2075-1729
2075-1729
DOI:10.3390/life13122268