Influence of reconstruction algorithms on image quality in SPECT myocardial perfusion imaging

Summary Introduction We investigated if image‐ and diagnostic quality in SPECT MPI could be maintained despite a reduced acquisition time adding Depth Dependent Resolution Recovery (DDRR) for image reconstruction. Images were compared with filtered back projection (FBP) and iterative reconstruction...

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Veröffentlicht in:Clinical physiology and functional imaging Jg. 37; H. 6; S. 655 - 662
Hauptverfasser: Davidsson, Anette, Olsson, Eva, Engvall, Jan, Gustafsson, Agnetha
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Wiley Subscription Services, Inc 01.11.2017
Schlagworte:
Adenosine - administration & dosage
Adult
Aged
Algorithms
Bicycling
Cardiac-Gated Imaging Techniques
Computed tomography
Confidence intervals
Diagnostic systems
EKG
Electrocardiography
Evaluation
Exercise Test
Female
Frames
Gating
Heart diseases
Humans
Image acquisition
Image Interpretation, Computer-Assisted
Image processing
Image quality
Image reconstruction
Ischemia
Male
Middle Aged
MPI SPECT
Myocardial Ischemia - diagnostic imaging
Myocardial Ischemia - physiopathology
Myocardial Perfusion Imaging - methods
noise regularization
Nuclear medicine
Observer Variation
Organophosphorus Compounds - administration & dosage
Organotechnetium Compounds - administration & dosage
Perfusion
Predictive Value of Tests
Quality
Radiopharmaceuticals - administration & dosage
Regression analysis
Reproducibility of Results
resolution recovery
Single photon emission computed tomography
Single Photon Emission Computed Tomography Computed Tomography
Statistical analysis
Vasodilator Agents - administration & dosage
Visual Grading Regression
Visual observation
resolution recovery
image quality
noise regularization
MPI SPECT
Visual Grading Regression
ISSN:1475-0961, 1475-097X, 1475-097X
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Zusammenfassung:Summary Introduction We investigated if image‐ and diagnostic quality in SPECT MPI could be maintained despite a reduced acquisition time adding Depth Dependent Resolution Recovery (DDRR) for image reconstruction. Images were compared with filtered back projection (FBP) and iterative reconstruction using Ordered Subsets Expectation Maximization with (IRAC) and without (IRNC) attenuation correction (AC). Materials and methods Stress‐ and rest imaging for 15 min was performed on 21 subjects with a dual head gamma camera (Infinia Hawkeye; GE Healthcare), ECG‐gating with 8 frames/cardiac cycle and a low‐dose CT‐scan. A 9 min acquisition was generated using five instead of eight gated frames and was reconstructed with DDRR, with (IRACRR) and without AC (IRNCRR) as well as with FBP. Three experienced nuclear medicine specialists visually assessed anonymized images according to eight criteria on a four point scale, three related to image quality and five to diagnostic confidence. Statistical analysis was performed using Visual Grading Regression (VGR). Results Observer confidence in statements on image quality was highest for the images that were reconstructed using DDRR (P<0·01 compared to FBP). Iterative reconstruction without DDRR was not superior to FBP. Interobserver variability was significant for statements on image quality (P<0·05) but lower in the diagnostic statements on ischemia and scar. The confidence in assessing ischemia and scar was not different between the reconstruction techniques (P = n.s.). Conclusion SPECT MPI collected in 9 min, reconstructed with DDRR and AC, produced better image quality than the standard procedure. The observers expressed the highest diagnostic confidence in the DDRR reconstruction.
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ISSN:1475-0961
1475-097X
1475-097X
DOI:10.1111/cpf.12354