Biomarkers: diagnosis and risk assessment in sepsis

Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers...

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Vydáno v:Clinics in chest medicine Ročník 29; číslo 4; s. 591
Hlavní autoři: Ventetuolo, Corey E, Levy, Mitchell M
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.12.2008
Témata:
Biomarkers - blood
C-Reactive Protein - metabolism
Calcitonin - blood
Calcitonin Gene-Related Peptide
Humans
Interleukin-6 - blood
Macrophages - immunology
Membrane Glycoproteins - blood
Monocytes - immunology
Neutrophils - immunology
Predictive Value of Tests
Prognosis
Protein Precursors - blood
Receptors, Immunologic - blood
Risk Assessment
Sepsis - diagnosis
Sepsis - immunology
Sepsis - therapy
Shock, Septic - diagnosis
Shock, Septic - immunology
Shock, Septic - therapy
Triggering Receptor Expressed on Myeloid Cells-1
ISSN:1557-8216, 1557-8216
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Popis
Shrnutí:Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1557-8216
1557-8216
DOI:10.1016/j.ccm.2008.07.001