Biomarkers: diagnosis and risk assessment in sepsis
Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers...
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| Published in: | Clinics in chest medicine Vol. 29; no. 4; p. 591 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
01.12.2008
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| Subjects: | |
| ISSN: | 1557-8216, 1557-8216 |
| Online Access: | Get more information |
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| Abstract | Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels. |
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| AbstractList | Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels. Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels.Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels. |
| Author | Ventetuolo, Corey E Levy, Mitchell M |
| Author_xml | – sequence: 1 givenname: Corey E surname: Ventetuolo fullname: Ventetuolo, Corey E organization: Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH 8, Room 101, 622 W. 168th Street, New York City, NY 10032, USA – sequence: 2 givenname: Mitchell M surname: Levy fullname: Levy, Mitchell M |
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| Snippet | Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers... |
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| SubjectTerms | Biomarkers - blood C-Reactive Protein - metabolism Calcitonin - blood Calcitonin Gene-Related Peptide Humans Interleukin-6 - blood Macrophages - immunology Membrane Glycoproteins - blood Monocytes - immunology Neutrophils - immunology Predictive Value of Tests Prognosis Protein Precursors - blood Receptors, Immunologic - blood Risk Assessment Sepsis - diagnosis Sepsis - immunology Sepsis - therapy Shock, Septic - diagnosis Shock, Septic - immunology Shock, Septic - therapy Triggering Receptor Expressed on Myeloid Cells-1 |
| Title | Biomarkers: diagnosis and risk assessment in sepsis |
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