Biomarkers: diagnosis and risk assessment in sepsis

Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers...

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Bibliographic Details
Published in:Clinics in chest medicine Vol. 29; no. 4; p. 591
Main Authors: Ventetuolo, Corey E, Levy, Mitchell M
Format: Journal Article
Language:English
Published: United States 01.12.2008
Subjects:
Biomarkers - blood
C-Reactive Protein - metabolism
Calcitonin - blood
Calcitonin Gene-Related Peptide
Humans
Interleukin-6 - blood
Macrophages - immunology
Membrane Glycoproteins - blood
Monocytes - immunology
Neutrophils - immunology
Predictive Value of Tests
Prognosis
Protein Precursors - blood
Receptors, Immunologic - blood
Risk Assessment
Sepsis - diagnosis
Sepsis - immunology
Sepsis - therapy
Shock, Septic - diagnosis
Shock, Septic - immunology
Shock, Septic - therapy
Triggering Receptor Expressed on Myeloid Cells-1
ISSN:1557-8216, 1557-8216
Online Access:Get more information
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Summary:Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1557-8216
1557-8216
DOI:10.1016/j.ccm.2008.07.001