24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk

The relation between sodium intake and cardiovascular disease is controversial. This study used individual-participant data from six prospective cohorts of healthy adults. Higher sodium and lower potassium intakes, estimated from multiple 24-hour urine samples, were associated in a dose-dependent ma...

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Bibliographic Details
Published in:The New England journal of medicine Vol. 386; no. 3; pp. 252 - 263
Main Authors: Ma, Yuan, He, Feng J, Sun, Qi, Yuan, Changzheng, Kieneker, Lyanne M, Curhan, Gary C, MacGregor, Graham A, Bakker, Stephan J.L, Campbell, Norm R.C, Wang, Molin, Rimm, Eric B, Manson, JoAnn E, Willett, Walter C, Hofman, Albert, Gansevoort, Ron T, Cook, Nancy R, Hu, Frank B
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 20.01.2022
Subjects:
Adult
Aged
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cardiovascular Diseases - prevention & control
Cerebral infarction
Diet
Excretion
Female
Gastroenterology
Heart attacks
Heart Disease Risk Factors
Humans
Hypertension
Incidence
Male
Medical personnel
Middle Aged
Myocardial infarction
Nurses
Nutrition
Potassium
Potassium - administration & dosage
Potassium - urine
Prospective Studies
Sodium
Sodium - urine
Sodium, Dietary - administration & dosage
Sodium, Dietary - adverse effects
Stroke
Systematic review
Urine
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Summary:The relation between sodium intake and cardiovascular disease is controversial. This study used individual-participant data from six prospective cohorts of healthy adults. Higher sodium and lower potassium intakes, estimated from multiple 24-hour urine samples, were associated in a dose-dependent manner with a higher cardiovascular risk.
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa2109794