TBX2 controls a proproliferative gene expression program in melanoma

Senescence shapes embryonic development, plays a key role in aging, and is a critical barrier to cancer initiation, yet how senescence is regulated remains incompletely understood. TBX2 is an antisenescence T-box family transcription repressor implicated in embryonic development and cancer. However,...

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Bibliographic Details

Published in:	Genes & development Vol. 35; no. 23-24; p. 1657
Main Authors:	Lu, Sizhu, Louphrasitthiphol, Pakavarin, Goradia, Nishit, Lambert, Jean-Philippe, Schmidt, Johannes, Chauhan, Jagat, Rughani, Milap G, Larue, Lionel, Wilmanns, Matthias, Goding, Colin R
Format:	Journal Article
Language:	English
Published:	United States 01.12.2021
Subjects:	senescence DNA binding specificity proliferation cell cycle DNA binding TBX2
ISSN:	1549-5477, 1549-5477
Online Access:	Get more information
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