Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation

Albuminuria is a key instigator of tubulointerstitial inflammation associated with CKD, but the mechanism through which filtered albumin propagates renal injury remains unclear. In this study, we explored the role in this process of exosome mRNA released from tubular epithelial cells (TECs). Compare...

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Vydané v:	Journal of the American Society of Nephrology Ročník 29; číslo 3; s. 919
Hlavní autori:	Lv, Lin-Li, Feng, Ye, Wen, Yi, Wu, Wei-Jun, Ni, Hai-Feng, Li, Zuo-Lin, Zhou, Le-Ting, Wang, Bin, Zhang, Jian-Dong, Crowley, Steven D, Liu, Bi-Cheng
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2018
Predmet:	albuminuria CCL2 macrophages mRNA exosome extracellular vesicle
ISSN:	1533-3450, 1533-3450
On-line prístup:	Zistit podrobnosti o prístupe
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