Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation

Albuminuria is a key instigator of tubulointerstitial inflammation associated with CKD, but the mechanism through which filtered albumin propagates renal injury remains unclear. In this study, we explored the role in this process of exosome mRNA released from tubular epithelial cells (TECs). Compare...

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Bibliographic Details

Published in:	Journal of the American Society of Nephrology Vol. 29; no. 3; p. 919
Main Authors:	Lv, Lin-Li, Feng, Ye, Wen, Yi, Wu, Wei-Jun, Ni, Hai-Feng, Li, Zuo-Lin, Zhou, Le-Ting, Wang, Bin, Zhang, Jian-Dong, Crowley, Steven D, Liu, Bi-Cheng
Format:	Journal Article
Language:	English
Published:	United States 01.03.2018
Subjects:	albuminuria CCL2 macrophages mRNA exosome extracellular vesicle
ISSN:	1533-3450, 1533-3450
Online Access:	Get more information
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