Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation

Albuminuria is a key instigator of tubulointerstitial inflammation associated with CKD, but the mechanism through which filtered albumin propagates renal injury remains unclear. In this study, we explored the role in this process of exosome mRNA released from tubular epithelial cells (TECs). Compare...

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Veröffentlicht in:	Journal of the American Society of Nephrology Jg. 29; H. 3; S. 919
Hauptverfasser:	Lv, Lin-Li, Feng, Ye, Wen, Yi, Wu, Wei-Jun, Ni, Hai-Feng, Li, Zuo-Lin, Zhou, Le-Ting, Wang, Bin, Zhang, Jian-Dong, Crowley, Steven D, Liu, Bi-Cheng
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2018
Schlagworte:	albuminuria CCL2 macrophages mRNA exosome extracellular vesicle
ISSN:	1533-3450, 1533-3450
Online-Zugang:	Weitere Angaben
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