An electrochemical nanobiosensor for plasma miRNA-155, based on graphene oxide and gold nanorod, for early detection of breast cancer

Circulating miRNAs are emerging as novel reliable biomarkers for early detection of cancer diseases. Through combining the advantages of electrochemical methods and nanomaterials with the selectivity of the oligo-hybridization-based biosensors, a novel electrochemical nanobiosensor for plasma miR-15...

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Bibliographic Details
Published in:	Biosensors & bioelectronics Vol. 77; pp. 99 - 106
Main Authors:	Azimzadeh, Mostafa, Rahaie, Mahdi, Nasirizadeh, Navid, Ashtari, Khadijeh, Naderi-Manesh, Hossein
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 15.03.2016
Subjects:	biomarkers Biomarkers, Tumor - blood Biosensing Techniques - instrumentation Biosensors Breast Breast cancer breast neoplasms Breast Neoplasms - blood Breast Neoplasms - diagnosis Cancer Circulating miRNA Conductometry - instrumentation detection limit Early detection Early Detection of Cancer - instrumentation Electrochemical electrochemistry Electrodes energy-dispersive X-ray analysis Equipment Design Equipment Failure Analysis glassy carbon electrode gold Gold - chemistry Graphene graphene oxide Graphite - chemistry image analysis Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure microRNA MicroRNAs - blood MiR-155 Nanobiosensor nanorods Nanostructure Nanotechnology - instrumentation Nanotubes - chemistry Nanotubes - ultrastructure Oxides - chemistry Reproducibility of Results Ribonucleic acids scanning electron microscopes Scanning electron microscopy Sensitivity and Specificity spectroscopy transmission electron microscopes transmission electron microscopy RuO2 ITO HRP HQ AuNP GNR Circulating miRNA Early detection BQ QD Pd Nanobiosensor MB SPCE SPGE MiR-155 OsO2 Amp TMB GO GCE Breast cancer EIS AP DNA TN SWV MWCNTs LNA Electrochemical
ISSN:	0956-5663, 1873-4235
Online Access:	Get full text
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