Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

Obesity and type 2 diabetes (T2D) are metabolic disorders that are linked to microbiome alterations. However, their co-occurrence poses challenges in disentangling microbial features unique to each condition. We analyzed gut microbiomes of lean non-diabetic (n = 633), obese non-diabetic (n = 494), a...

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Veröffentlicht in:	Cell host & microbe Jg. 26; H. 2; S. 252
Hauptverfasser:	Thingholm, Louise B, Rühlemann, Malte C, Koch, Manja, Fuqua, Brie, Laucke, Guido, Boehm, Ruwen, Bang, Corinna, Franzosa, Eric A, Hübenthal, Matthias, Rahnavard, Ali, Frost, Fabian, Lloyd-Price, Jason, Schirmer, Melanie, Lusis, Aldons J, Vulpe, Chris D, Lerch, Markus M, Homuth, Georg, Kacprowski, Tim, Schmidt, Carsten O, Nöthlings, Ute, Karlsen, Tom H, Lieb, Wolfgang, Laudes, Matthias, Franke, Andre, Huttenhower, Curtis
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 14.08.2019
Schlagworte:	Animals Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Biodiversity Diabetes Mellitus, Type 2 - complications Diet Dietary Supplements Feces - microbiology Female Gastrointestinal Microbiome - physiology Germany Humans Iron - metabolism Magnesium - metabolism Male Metabolic Diseases - complications Metagenomics Mice Mice, Inbred C57BL Multivariate Analysis Nutrition Assessment Obesity - complications Obesity - microbiology Serum - metabolism Germany nutrition type 2 diabetes dietary supplements iron magnesium medication metabolic disease microbiome obesity
ISSN:	1934-6069, 1934-6069
Online-Zugang:	Weitere Angaben
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