Biological effects of inhaled hydraulic fracturing sand dust. III. Cytotoxicity and pro-inflammatory responses in cultured murine macrophage cells

Cultured murine macrophages (RAW 264.7) were used to investigate the effects of fracking sand dust (FSD) for its pro-inflammatory activity, in order to gain insight into the potential toxicity to workers associated with inhalation of FSD during hydraulic fracturing. While the role of respirable crys...

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Veröffentlicht in:	Toxicology and applied pharmacology Jg. 408; S. 115281
Hauptverfasser:	Olgun, Nicole S., Morris, Anna M., Stefaniak, Aleksandr B., Bowers, Lauren N., Knepp, Alycia K., Duling, Matthew G., Mercer, Robert R., Kashon, Michael L., Fedan, Jeffrey S., Leonard, Stephen S.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.12.2020
Schlagworte:	Animals Cell Survival Comet Assay Cytotoxicity Dust Fracking sand dust Hydraulic Fracking Inflammation Interleukin-6 Macrophages Mice Occupational exposure RAW 264.7 Cells Reactive Oxygen Species Sand Tumor Necrosis Factor-alpha Cytotoxicity Inflammation Occupational exposure Macrophages Fracking sand dust
ISSN:	0041-008X, 1096-0333, 1096-0333
Online-Zugang:	Volltext
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