Key for crossing the BBB with nanoparticles: the rational design

Central nervous system diseases are a heavy burden on society and health care systems. Hence, the delivery of drugs to the brain has gained more and more interest. The brain is protected by the blood–brain barrier (BBB), a selective barrier formed by the endothelial cells of the cerebral microvessel...

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Bibliographic Details
Published in:	Beilstein journal of nanotechnology Vol. 11; no. 1; pp. 866 - 883
Main Authors:	Lombardo, Sonia M, Schneider, Marc, Türeli, Akif E, Günday Türeli, Nazende
Format:	Journal Article
Language:	English
Published:	Frankfurt am Main Beilstein-Institut zur Föerderung der Chemischen Wissenschaften 04.06.2020 Beilstein-Institut
Subjects:	Blood-brain barrier blood–brain barrier (bbb) Brain diseases Central nervous system Disease drug delivery Drug delivery systems Drugs Endothelial cells gold nanoparticles (aunps) Homeostasis Ligands liposomes nanomedicine Nanoparticles Nanoscience Nanotechnology Neurological disorders Neurotoxicity Physiology polymeric nanoparticles Proteins Review solid lipid nanoparticles superparamagnetic iron oxide nanoparticles (spions) Surface properties
ISSN:	2190-4286, 2190-4286
Online Access:	Get full text
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