An integrated approach to identify environmental modulators of genetic risk factors for complex traits

Complex traits and diseases can be influenced by both genetics and environment. However, given the large number of environmental stimuli and power challenges for gene-by-environment testing, it remains a critical challenge to identify and prioritize specific disease-relevant environmental exposures....

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Vydáno v:	American journal of human genetics Ročník 108; číslo 10; s. 1866
Hlavní autoři:	Balliu, Brunilda, Carcamo-Orive, Ivan, Gloudemans, Michael J, Nachun, Daniel C, Durrant, Matthew G, Gazal, Steven, Park, Chong Y, Knowles, David A, Wabitsch, Martin, Quertermous, Thomas, Knowles, Joshua W, Montgomery, Stephen B
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 07.10.2021
Témata:	Autoimmune Diseases - etiology Autoimmune Diseases - pathology Gene-Environment Interaction Genetic Predisposition to Disease Genome-Wide Association Study Humans Mental Disorders - etiology Mental Disorders - pathology Metabolic Diseases - etiology Metabolic Diseases - pathology Multifactorial Inheritance Phenotype Polymorphism, Single Nucleotide Quantitative Trait Loci GWAS colocalization eQTL gene-by-environment interactions gene expression
ISSN:	1537-6605, 1537-6605
On-line přístup:	Zjistit podrobnosti o přístupu
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