An integrated approach to identify environmental modulators of genetic risk factors for complex traits

Complex traits and diseases can be influenced by both genetics and environment. However, given the large number of environmental stimuli and power challenges for gene-by-environment testing, it remains a critical challenge to identify and prioritize specific disease-relevant environmental exposures....

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Bibliographic Details
Published in:	American journal of human genetics Vol. 108; no. 10; p. 1866
Main Authors:	Balliu, Brunilda, Carcamo-Orive, Ivan, Gloudemans, Michael J, Nachun, Daniel C, Durrant, Matthew G, Gazal, Steven, Park, Chong Y, Knowles, David A, Wabitsch, Martin, Quertermous, Thomas, Knowles, Joshua W, Montgomery, Stephen B
Format:	Journal Article
Language:	English
Published:	United States 07.10.2021
Subjects:	Autoimmune Diseases - etiology Autoimmune Diseases - pathology Gene-Environment Interaction Genetic Predisposition to Disease Genome-Wide Association Study Humans Mental Disorders - etiology Mental Disorders - pathology Metabolic Diseases - etiology Metabolic Diseases - pathology Multifactorial Inheritance Phenotype Polymorphism, Single Nucleotide Quantitative Trait Loci GWAS colocalization eQTL gene-by-environment interactions gene expression
ISSN:	1537-6605, 1537-6605
Online Access:	Get more information
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