Finite and infinite dosing: Difficulties in measurements, evaluations and predictions

Due to the increased demand for reliable data regarding penetration into and permeation across human skin, assessment of the absorption of xenobiotics has been gaining in importance steadily. In vitro experiments allow for determining these data faster and more easily than in vivo experiments. Howev...

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Veröffentlicht in:	Advanced drug delivery reviews Jg. 65; H. 2; S. 278 - 294
Hauptverfasser:	Selzer, Dominik, Abdel-Mottaleb, Mona M.A., Hahn, Tsambika, Schaefer, Ulrich F., Neumann, Dirk
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.02.2013
Schlagworte:	Animals Concentration-depth profile Dose-Response Relationship, Drug Drug Delivery Systems Humans In vitro In vivo Models, Theoretical Penetration Permeability Permeation Skin - metabolism Skin Absorption Tape stripping Xenobiotics - administration & dosage Xenobiotics - pharmacokinetics Tape stripping In vivo Penetration In vitro Concentration-depth profile Permeation
ISSN:	0169-409X, 1872-8294, 1872-8294
Online-Zugang:	Volltext
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