Finite and infinite dosing: Difficulties in measurements, evaluations and predictions

Due to the increased demand for reliable data regarding penetration into and permeation across human skin, assessment of the absorption of xenobiotics has been gaining in importance steadily. In vitro experiments allow for determining these data faster and more easily than in vivo experiments. Howev...

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Vydáno v:	Advanced drug delivery reviews Ročník 65; číslo 2; s. 278 - 294
Hlavní autoři:	Selzer, Dominik, Abdel-Mottaleb, Mona M.A., Hahn, Tsambika, Schaefer, Ulrich F., Neumann, Dirk
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier B.V 01.02.2013
Témata:	Animals Concentration-depth profile Dose-Response Relationship, Drug Drug Delivery Systems Humans In vitro In vivo Models, Theoretical Penetration Permeability Permeation Skin - metabolism Skin Absorption Tape stripping Xenobiotics - administration & dosage Xenobiotics - pharmacokinetics Tape stripping In vivo Penetration In vitro Concentration-depth profile Permeation
ISSN:	0169-409X, 1872-8294, 1872-8294
On-line přístup:	Získat plný text
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